Drug class

ACE inhibitors clinical trials

A class of medicines: the studies that test any of its 14 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones. In MeSH: Angiotensin-Converting Enzyme Inhibitors.

studies test it: 391
open now: 24
in phase 3: 80
first study started: 1992

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Medicines in this class

Studies that test each. A study of two counts under both, and once above.

Ramipril: 108
Lisinopril: 79
Enalapril: 66
Perindopril: 38
Benazepril: 27
Captopril: 25
Trandolapril: 15
Quinapril: 11
Fosinopril: 8
Enalaprilat: 3
Zofenopril: 3
Moexipril: 3
Imidapril: 2
Capozide: 1

Studies by the year they started

386 studies that test it; most in 2007 (33)

Studies that test ACE inhibitors, by start year
Year	Studies
1992	1
1993	2
1994	1
1995	2
1997	3
1998	3
1999	5
2000	9
2001	6
2002	15
2003	13
2004	32
2005	22
2006	24
2007	33
2008	26
2009	19
2010	19
2011	10
2012	16
2013	8
2014	10
2015	12
2016	11
2017	11
2018	13
2019	12
2020	6
2021	9
2022	8
2023	3
2024	10
2025	5
2026	7

By phase

A phase 1/2 study counts in both.

Early Phase 1: 5
Phase 1: 63
Phase 2: 66
Phase 3: 80
Phase 4: 135
No phase: 58

What it is tested for

Each study’s main condition, where its own words name it, so a study counts once.

Hypertension: 86
Essential Hypertension: 12
Diabetic Nephropathies: 11
Renal Insufficiency, Chronic: 8
Heart Failure: 8
Cardiovascular Diseases: 7
Diabetes Mellitus, Type 1: 6
Breast Neoplasms: 5
Cardiotoxicity: 5
Kidney Failure, Chronic: 5
Diabetes Mellitus, Type 2: 5
Coronary Artery Disease: 4

Who runs them

Industry 114 · Other 277

Boehringer Ingelheim (10) · Novartis (10) · GlaxoSmithKline (8) · Dr. Reddy's Laboratories Limited (8) · Teva Pharmaceuticals USA (7) · Sanofi (7) · Vanderbilt University (7) · National Heart, Lung, and Blood Institute (NHLBI) (6)

Studies

Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.

Testing one of them · 391

See all 391 studies that test one of the ace inhibitors →

What changed recently

From the registry's own updates since Oct 14, 2026.

Newly registered1

Ramipril vs. Amlodipine in Pediatric Hemodialysis PatientsOct 19, 2026NCT07879560

Codes

What other systems call ACE inhibitors · ClinicalTrials.gg INT006981

MeSH (NLM) D000806Angiotensin-Converting Enzyme InhibitorsOne source ClinicalTrials.gov

System	Code	Name there	Checked by
MeSH (NLM)	D000806	Angiotensin-Converting Enzyme Inhibitors	One source ClinicalTrials.gov

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.