SupplementDrug
Creatine clinical trials
Includes 76 studies of Creatine monohydrate and 1 study of Creatine hydrochloride.
- studies test it
- 130
- open now
- 31
- in phase 3
- 13
- first study started
- 2000
Keep track of what changes. Save the Creatine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
128 studies that test it; most in 2026 (17)
| Year | Studies |
|---|---|
| 2000 | 1 |
| 2001 | 1 |
| 2002 | 2 |
| 2003 | 3 |
| 2004 | 3 |
| 2005 | 2 |
| 2006 | 2 |
| 2007 | 3 |
| 2008 | 1 |
| 2009 | 6 |
| 2010 | 5 |
| 2011 | 3 |
| 2012 | 5 |
| 2013 | 4 |
| 2014 | 7 |
| 2015 | 8 |
| 2016 | 3 |
| 2017 | 3 |
| 2018 | 4 |
| 2019 | 4 |
| 2020 | 4 |
| 2021 | 3 |
| 2022 | 8 |
| 2023 | 6 |
| 2024 | 12 |
| 2025 | 8 |
| 2026 | 17 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 4
- Phase 2
- 16
- Phase 3
- 13
- Phase 4
- 9
- No phase
- 87
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 6 · Other 124
University of Utah (8) · University of Sao Paulo (8) · Massachusetts General Hospital (6) · University of Regina (5) · Perry Renshaw (4) · University of Saskatchewan (4) · GlaxoSmithKline (3) · University of British Columbia (2)
Often tested with
Tested in the same studies.
5-Hydroxytryptophan (4) · Omega-3 fatty acid (3) · Acetylcysteine (2) · Arginine (2) · Tyrosol (2) · Whey Proteins (2) · Niacinamide (2) · Betaine (2)
Studies
Open first, then newest update. How each study uses Creatine is read from its arms, and is right about nine times in ten.
Testing it · 130
- The Effects of Tyrosol and Creatine on Exercise Performance and Cognition in Healthy AdultsRecruitingNot applicableApplied Science & Performance InstituteNCT07756658Written as Creatine Monohydrate
- 5-HTP and Creatine for Depression R33 PhaseRecruitingPhase 2University of UtahNCT05895747Written as Low Dose Creatine Monohydrate
- Creatine and Resistance Training in Older Adults With Mild Cognitive ImpairmentRecruitingNot applicableWestern University, CanadaNCT06948149Written as Creatine monohydrate
- Creatine and Perioperative Brain HealthNot yet recruitingNot applicableMassachusetts General HospitalNCT07310043Written as Creatine monohydrate
- Creatine Supplementation in Pediatric Brain InjuryNot yet recruitingNot applicableSpaulding Rehabilitation HospitalNCT07756060Written as Creatine monohydrate
- Dietary Supplements and Middle Aged Women (Creatine)RecruitingNot applicableLoughborough UniversityNCT07729930Written as Creatine Monohydrate
- Effects of Creatine and Carbohydrate Supplementation on Endurance PerformanceNot yet recruitingNot applicableCalifornia Polytechnic State University-San Luis ObispoNCT07712653Written as Creatine Monohydrate
- Creatine Supplementation in Concussion RecoveryRecruitingNot applicableSan Diego State UniversityNCT06208813Written as Creatine
- Creatine Supplementation and Resistance Training to Improve Sarcopenia Parameters in Patients With Prostate Cancer After Androgen Deprivation TherapyRecruitingNot applicableUniversity of Sao PauloNCT07463092Written as Creatine Monohydrate
- Creatine Supplementation During GLP-1a TherapyRecruitingNot applicableUniversity of SaskatchewanNCT07625202Written as Dietary supplementation during a 12 week resistance-training program (creatine)
- Creatine Supplementation and Resistance Training to Preserve Muscle Mass and Attenuate Cancer ProgressionRecruitingPhase 3University of UtahNCT06112990Written as creatine monohydrate
- Acute Pharmacokinetics of Create Wellness Gummies in Healthy AdultsRecruitingNot applicableUniversity of OklahomaNCT07579455Written as Creatine Monohydrate Powder
- Effects of Creatine and Heat Exposure on Exercise Performance and Body Water DistributionNot yet recruitingNot applicableUniversity of WindsorNCT07593014Written as Creatine Monohydrate
- Effect of Micronized Creatine Monohydrate on Muscle Mass, Strength and Performance in Older Adults Submitted to Total Knee ArthroplastyRecruitingNot applicableConsorci Sanitari del MaresmeNCT06925880Written as Creatine Monohydrate
- Effects of Short-term Acute Creatine Supplementation on Power, Speed and Muscular Strengths in Young Football PlayersNot yet recruitingNot applicableSt. Mary's University, TwickenhamNCT07475676Written as Creatine Monohydrate
- Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the HeatRecruitingNot applicableUniversity of Northern IowaNCT07472426Written as Creatine Monohydrate
- Creatine and Cognitive Health in Patients With Early-stage Breast Cancer During and After Chemotherapy TreatmentNot yet recruitingPhase 3D'Or Institute for Research and EducationNCT07372144Written as Creatine
- THRIVE Well Cancer FDTN/Exercise_Creatine SupplementationRecruitingNot applicableThe University of Texas Medical Branch, GalvestonNCT06395506Written as Creatine
- Load and Hold: Impact of 7-Day Creatine Monohydrate Loading on Breath-Hold Cycling PerformanceEnrolling by invitationNot applicableHarokopio UniversityNCT07233707Written as Creatine Monohydrate
- Effect of Supplementation With Creatine on the Recovery of Ischemic StrokeRecruitingNot applicableFundació d'investigació Sanitària de les Illes BalearsNCT06576466Written as Creatine monohydrate
See all 130 studies that test Creatine →
Given in every arm · 3 — Creatine is usual care beside what is tested
- PRecision gerOMedicinE: Tailored Healthy agEing With Lifestyle, sUpplements and drugS (PROMETHEUS)RecruitingNot applicableNational University of SingaporeNCT07451496Written as Creatine Monohydrate
- Exercise, Creatine and Coenzyme Q10 for Childhood MyositisCompletedNot applicableThe Hospital for Sick ChildrenNCT04286178Written as creatine monohydrate
- Combination Therapy Selection Trial in Amyotrophic Lateral SclerosisCompletedPhase 2Columbia UniversityNCT00355576Written as Creatine
As the comparator · 4 — what is tested is compared with Creatine
- Changing in Plasma Concentration of a New Form of CreatineNot yet recruitingNot applicableUniversity of PadovaNCT07838805Written as Active Comparator: Creatine Monohydrate
- Impact of OptiCreatine on Plasma Creatine and Gastrointestinal Effects in Males and FemalesCompletedNot applicableTSI Group LTDNCT07225335Written as Creatine Monohydrate
- Assessment of the Efficacy of Carnipure® AAS on Body Composition, Muscle Thickness, and Strength Adaptations in Healthy MenCompletedNot applicableApplied Science & Performance InstituteNCT05681806Written as Creatine Monohydrate
- Guanidinoacetic Acid With Creatine Compared With Creatine Alone for Tissue Bioenergetics, Hyperhomocysteinemia and Exercise PerformanceCompletedNot applicableUniversity of Novi Sad, Faculty of Sport and Physical EducationNCT03350282Written as Creatine
Codes
What other systems call Creatine · ClinicalTrials.gg INT007269
- MeSH (NLM) D003401CreatineConfirmed NLM, Wikidata
- UNII (FDA) MU72812GK0CREATINEConfirmed FDA, NLM, Wikidata
- RxNorm 2907Confirmed FDA, Wikidata
- Wikidata Q106345487creatine zwitterionConfirmed FDA, NLM, Wikidata
- Wikidata Q223600creatineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C37937CreatineOne source FDA
- DrugBank DB00148One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D003401 | Creatine | Confirmed NLM, Wikidata |
| UNII (FDA) | MU72812GK0 | CREATINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2907 | — | Confirmed FDA, Wikidata |
| Wikidata | Q106345487 | creatine zwitterion | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q223600 | creatine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C37937 | Creatine | One source FDA |
| DrugBank | DB00148 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.