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Active, not recruitingNCT06704997Updated Oct 7, 2026

Machine Learning to Predict Factors Affecting Rehabilitation Length of Stay and Healthcare Costs for Neurological Rehabilitation

An observational study in Stroke, Acquired Brain Injury and Traumatic Brain Injury, sponsored by Tan Tock Seng Hospital. Active, not recruiting at 1 site in Singapore. Open to participants aged 21 Years to 100 Years. Per ClinicalTrials.gov, last updated 2026-10-07.

Sponsored by Tan Tock Seng Hospital · Observational

Updated Oct 7, 2026Primary completion movedStudy completion movedGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
10,000
Ages
21 Years to 100 Years
Sex
All
01

Study summary

The aim of this retrospective study is to ascertain total direct costs, rehabilitation length of stay (RLOS) and factors associated with RLOS for neurological inpatient rehabilitation at the tertiary care hospital.

Read the detailed description

The aim of the study is to identify factors that influence RLOS and the correlated costs for neurological rehabilitation in tertiary rehab using data extracted from EPIC. It is also aimed to identify the median direct costs to find out the main contributors to the costs in the local population. Lastly, the study aims to utilise artificial intelligence or machine learning to analyse the compiled data to develop a predictive model. The model aspires to understand factors associated with extended RLOS and to predict RLOS of patients who require neurological rehabilitation, aiding preemptive measures.

02

Conditions studied

  • Stroke
  • Acquired Brain Injury
  • Traumatic Brain Injury
  • Brain Tumor
  • Central Nervous System Infections
  • Polytrauma

Keywords

  • Rehabilitation
  • Length of Stay
  • Stroke
  • Traumatic Brain Injury
  • Brain tumour
  • Cancer
  • Trauma
  • Acquired Brain Injury
  • Healthcare
  • Hospitalisation costs
03

In context

Stroke

8,255 studies on the registry are indexed under Stroke; 2,056 are open to participants now.

This study's planned enrollment of 10,000 is above the median of 152 across 1,968 observational studies indexed under Stroke.

Browse Stroke studies →

Lead sponsor

Tan Tock Seng Hospital is the lead sponsor of 108 studies on the registry; 19 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
21 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients who have admitted to the rehabilitation ward during their inpatient episode for neurological rehabilitation.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • All patients who completed inpatient rehabilitation with the index conditions in their discharge summaries

Exclusion criteria

Exclusion Criteria:

  • Did not complete inpatient rehabilitation as they are discharged against medical advice
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
10,000 participants (estimated)
Patient registry
No

Groups and cohorts

  • Patients with tertiary neurological rehabilitation

    Patients with confirmed diagnosis of stroke, acquired brain injuries, traumatic brain injuries, brain tumours, central nervous system infections and polytrauma from acute neurological or neurosurgical units in Singapore. The cohort will be selected from the TTSH Rehabilitation Centre (TTSH RC) admissions from year 2016 to the present.

06

What researchers measure

Primary outcomes

  1. Rehabilitation length of stay

    Duration of which patient is admitted to and discharge from the rehabilitation ward.

    Time frame: 1998-2022

  2. Hospital bill

    Bill size of patient's stay in the rehabilitation ward, including subsidies, insurance and copayment.

    Time frame: 2012-2022

  3. Housing type

    Type of housing to look at the socio-economics status of the patients.

    Time frame: 2014-2023

07

Study locations

1 site
08

References and documents

Individual participant data

Plan to share: Undecided — PI need to verify the quality of the data as extraction will involve accessing Ministry of Health government website to obtain deidentified data set

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedDate before it movedWhere the date was before it moved

Started Jun 2024 (actual). Primary completion is estimated for Dec 2026, 30 months after the start.

Since we started tracking on Sep 25, 2026, the dates moved once, on Oct 7, 2026: primary completion Dec 2025 → Dec 2026 and completion Dec 2026 → Dec 2027.

Earlier changes are on the record history on ClinicalTrials.gov ↗

How these figures are worked out, and which studies are left out of them.

Registered
Nov 22, 2024
First posted
Nov 26, 2024
StartActual
Jun 1, 2024
Primary completionEst.
Dec 31, 2026was Dec 2025
CompletionEst.
Dec 31, 2027was Dec 2026
Last update
Oct 7, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Primary completion
Dec 31, 2025→Dec 31, 2026
Oct 7, 2026
Study completion
Dec 31, 2026→Dec 31, 2027
Oct 7, 2026
Show all 1 update
  1. Oct 7, 2026
    Primary completion Dec 31, 2025→Dec 31, 2026
    Study completion Dec 31, 2026→Dec 31, 2027
    + 2 other changes: index terms and verification date

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT06704997
Responsible party
Chua Sui Geok, Karen (Senior Consultant Dr ( MD), Tan Tock Seng Hospital) — Principal investigator
First posted
Nov 26, 2024
Start date
Jun 1, 2024
Primary completion
Dec 31, 2026 (estimated)
Completion
Dec 31, 2027 (estimated)
Last update
Oct 7, 2026

Study contacts

Dr Karen Chua, MBBS
principal investigator · Tan Tock Seng Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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