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Enrolling by invitationNCT07912411Updated Nov 3, 2026

Continuous Noninvasive Multimodal Neuromonitoring at the ICU After Cardiac Arrest

An observational study in Post-cardiac Arrest Brain Injury, sponsored by Maastricht University Medical Center. Enrolling by invitation at 1 site in Netherlands. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-11-03.

Sponsored by Maastricht University Medical Center · Observational

Updated Nov 3, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
100
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this observational study is to investigate the relationship between non-invasive brain monitoring measurements and neurological recovery six months after cardiac arrest in patients admitted to the intensive care unit (ICU).

After admission to the ICU, patients who have had a cardiac arrest will undergo non-invasive brain monitoring. Six months later, their neurological outcome will be assessed using a telephone interview with the patient or their caregiver.

Based on this assessment, patients will be classified as having either a good or poor neurological outcome. The study will then investigate whether the brain monitoring measurements can help distinguish between these two groups.

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Conditions studied

  • Post-cardiac Arrest Brain Injury
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In context

Brain Injuries

946 studies on the registry are indexed under Brain Injuries; 235 are open to participants now.

This study's planned enrollment of 100 is close to the median of 100 across 302 observational studies indexed under Brain Injuries.

Browse Brain Injuries studies →

Lead sponsor

Maastricht University Medical Center is the lead sponsor of 853 studies on the registry; 114 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult post-resuscitation patients admitted to the ICU, who are enrolled in the institutional post-resuscitation and neuroprognostication protocol and therefore comatose and mechanically ventilated.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Comatose (RASS -5), mechanically ventilated adults (≥ 18 years)
  • Resuscitated patients admitted to the ICU, for whom the institutional post-resuscitation and neuroprognostication protocol is initiated

Exclusion criteria

Exclusion Criteria:

  • Early moribund prognosis
  • Forehead wounds or traumatic abnormalities precluding sensor placement
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
100 participants (estimated)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Neurological outcome

    Determined by the the Cerebral Performance Category (CPC) score.

    Time frame: 6 months after ICU admission

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Study locations

1 site
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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Nov 3, 2026
Show all 1 update
  1. Nov 3, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

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Registry details

Key details

Study ID
NCT07912411
Collaborators
Maastricht University
Responsible party
Sponsor
First posted
Nov 3, 2026
Start date
Feb 19, 2024
Primary completion
Jun 1, 2027 (estimated)
Completion
Jun 1, 2027 (estimated)
Last update
Nov 3, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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