Post-Cardiac Arrest Syndrome clinical trials
The registry lists 31 studies for Post-Cardiac Arrest Syndrome across more than 10 countries. 11 are recruiting or about to start. 7 of them are mainly about Post-Cardiac Arrest Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.
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Status
Who runs them
Christian Hassager (2) · Peking University Third Hospital (2) · University of Aarhus (2) · Kagawa University (2) · National Taiwan University Hospital (2) · Region Skane (1) · Russian Federation of Anesthesiologists and Reanimatologists (1) · University Medical Center Groningen (1)
What is being tested here
Drugs under test in Post-Cardiac Arrest Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Xenon | 1 | 1 | 1 |
| Ascorbic Acid | 0 | 0 | 2 |
| Dexamethasone | 0 | 1 | 1 |
| Olanzapine | 0 | 1 | 1 |
| Infliximab | 0 | 0 | 1 |
| Cyclosporine | 0 | 1 | 1 |
| Methylprednisolone | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3, phase 3 first
- Sep 2027The Danish Out-of-Hospital Cardiac Arrest Study · Phase 3 · Christian Hassager
- Jan 2027The Holistic Health Care of Post-Cardiac Arrest Survivors: From Patient's Health to Family Resilience · National Taiwan University Hospital
- Feb 2027Cerebral Oximetry in Management of Post Cardiac Arrest · University of Calgary
Who these studies take
Of the 7 Post-Cardiac Arrest Syndrome studies recruiting now, 5 (71%) set no upper age limit and 1 (14%) stop at 75 or younger. 1 (14%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (14%) | 1 (14%) |
| 18 | 6 (86%) | 6 (86%) |
| 30 | 7 (100%) | 7 (100%) |
| 40 | 7 (100%) | 7 (100%) |
| 50 | 7 (100%) | 7 (100%) |
| 65 | 7 (100%) | 7 (100%) |
| 75 | 7 (100%) | 7 (100%) |
| 85 | 5 (71%) | 5 (71%) |
Across all 31 studies, recruiting or not: 6% stop at 75 or younger and 0% at 65; 6% take children; 0% are for women only and 0% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 15, 2026.
Newly registered1
- Minimal Sedation Versus Standard Continuous Sedation After Out-of-Hospital Cardiac ArrestOct 26, 2026NCT07895771
Studies
Recruiting first, then most recently updated. Showing 31 of 31. search them.
- Minimal Sedation Versus Standard Continuous Sedation After Out-of-Hospital Cardiac ArrestRecruitingNCT07895771Not applicable1 country
- Cerebral Oximetry in Management of Post Cardiac ArrestRecruitingNCT07829887Not applicable1 country
- The Holistic Health Care of Post-Cardiac Arrest Survivors: From Patient's Health to Family ResilienceRecruitingNCT048592701 country
- Breakthrough Platform Trial for PCASNot yet recruitingNCT07769086Not applicable1 country
- Clinical Cohort Construction Program of Peking University Third HospitalEnrolling by invitationNCT077621441 country
- Hypothermia Versus Normothermia After Extracorporeal Cardiopulmonary Resuscitation for Out-of-hospital Cardiac ArrestRecruitingNCT06776549Not applicable1 country
- Xenon for Neuroprotection During Post-Cardiac Arrest Syndrome in Comatose Survivors of an Out of Hospital Cardiac ArrestNot yet recruitingNCT03176186Phase 32 countries
- Lung-cOnservative Liquid VEntilation for the Induction of Ultra-Rapid COOLing After Cardiac ArrestNot yet recruitingNCT06798818Not applicable1 country
- Role of Candidate Proteins in Capillary Leakage During Acute Circulatory FailureRecruitingNCT055862821 country
- TIMECARD(TaIwan Network of Post-arrest ManagEment for CARDiac Arrest)IIRegistryRecruitingNCT062183291 country
- Post-Surgery Extracorporeal Life SupportRecruitingNCT043306511 country
- The Danish Out-of-Hospital Cardiac Arrest StudyActive, not recruitingNCT05895838Phase 31 country
- Survival After Cardiac Arrest: How New Treatment Guidelines Changed Patient Outcomes.CompletedNCT076498891 country
- TNF-α Antagonists Mitigate Systemic Inflammatory Response After Cardiac Arrest.Active, not recruitingNCT07176754Not applicable1 country
- Pulse Pressure and Outcomes After Out-of-Hospital Cardiac ArrestActive, not recruitingNCT075868781 country
- Cyclosporine A in Cardiac ArrestCompletedNCT01595958Phase 31 country
- Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest SurvivorsCompletedNCT04921189Phase 21 country
- Vitamin C in Post-cardiac ArrestCompletedNCT03509662Phase 21 country
- Intensive Care Unit Management After Cardiac ARrest in RussiaCompletedNCT046088251 country
- Steroid Treatment After Resuscitated Out-of-Hospital Cardiac ArrestCompletedNCT04624776Phase 21 country
- Prognostic Value of Ventricular Fibrillation Spectral Analysis in Sudden Cardiac DeathCompletedNCT032485571 country
- The Evaluation of Optimal Observation Period for Neurological Recovery in Post-arrest SurvivorsCompletedNCT049672611 country
- Blood Pressure and Cerebral Blood Flow After Cardiac ArrestStatus unknownNCT05434910Not applicable1 country
- Cytokine Adsorption in Post-cardiac Arrest Syndrome in Patients Requiring Extracorporeal Cardiopulmonary ResuscitationCompletedNCT03685383Not applicable1 country
- Pre-hospital Post ROSC Care: Are we Achieving Our Targets?Status unknownNCT04339257
- Cerebral Oxymetry and Neurological Outcome in Therapeutic HypothermiaCompletedNCT030240211 country
- The Effect of IABP Early Insertion on Mortality in Post Cardiac Arrest Patients With Acute Coronary SyndromeStatus unknownNCT03638609Not applicable1 country
- Histones and Free-plasma DNA After Cardiac ArrestCompletedNCT027331461 country
- The Complement Lectin Pathway After Cardiac ArrestStatus unknownNCT02826057Not applicable1 country
- Study of Survivors of Different Types of Cardiac Arrest and Their Neurological RecoveryStatus unknownNCT020337201 country
- Trial of Different Hypothermia Temperatures in Patients Recovered From Out-of-hospital Cardiac ArrestCompletedNCT01155622Phase 41 country