Appendicitis: all 419 studies

Page 1 of 5. Open to participants first (67), then studies with results posted, then the rest; newest registration first within each.

• Systemic and Tissue Inflammatory Biomarkers in Acute AppendicitisRecruitingNCT07926165
• Prospective Comparison of Pro-Adrenomedullin, C-Reactive Protein, and Neutrophil-to-Lymphocyte Ratio for Diagnosing Acute AppendicitisRecruitingNCT07889544
• Comparative Study Between Laparoscopic and Open Appendectomy of Complicated AppendicitisNot yet recruitingNCT07879235Not applicable
• Piperacillin/Tazobactam Versus Ceftriaxone and Metronidazole for Children With Perforated AppendicitisNot yet recruitingNCT07869095Phase 3
• Patient Choice Between Antibiotics and Appendectomy in Uncomplicated Appendicitis (FRENCH 47 - ALACARTE)Not yet recruitingNCT07857252Phase 2
• Immediate Laparoscopic Appendectomy Versus Interval Laparoscopic Appendectomy for Early Appendicular MassNot yet recruitingNCT07837531Not applicable
• Effect Of Specimen Extraction Site And Local Anesthesia On Postoperative Pain In Laparoscopic AppendectomyRecruitingNCT07824908Not applicable
• Laparoscopic vs Open Appendectomy in Obese PatientsNot yet recruitingNCT07822503Not applicable
• Video-Based Grading of Intraoperative Adverse Events in Pediatric Laparoscopic AppendectomyRecruitingNCT07794618
• Laparoscopic Appendectomy: Outcomes of 10 mmHg Versus 15 mmHg Intra-abdominal PressureNot yet recruitingNCT07727499Not applicable
• Primary Versus Delayed Wound Closure in Complicated Appendectomy (The HIEDI-Yemen Trial)Not yet recruitingNCT07688109Not applicable
• Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic AppendectomyRecruitingNCT07678086Not applicable
• Perforated Appendicitis and Postoperative Antibiotics Pilot TrialNot yet recruitingNCT07656636Not applicable
• Feasibility and Safety of a Pediatric ERAS Protocol for Laparoscopic AppendectomyRecruitingNCT07643285Not applicable
• Effects of Cartoons and Mobile Games on Preoperative Anxiety and Fear in Children With Appendicitis: An RCTRecruitingNCT07640230Not applicable
• Oral Lactulose for Gastrointestinal Recovery After Complex AppendectomyRecruitingNCT07589465Not applicable
• Efficacy of Non Operative Treatment With Amoxicillin/Clavulanic Acid Versus Surgical Treatment in Acute Uncomplicated Appendicitis in ChildrenNot yet recruitingNCT07587450Phase 3
• Diagnosis of Abdominal Pain Using RNA Levels: The NATURAL StudyRecruitingNCT07579312
• One Versus Five Days of Antibiotics After AppendectomyNot yet recruitingNCT07563933Not applicable
• Out-patiente Management for Gangrenous Acute Appendicitis: The PENDI-CSI II Randomized Clinical Trial.RecruitingNCT07521969Not applicable
• Comparison of Diagnostic Methods in Patients Operated for Suspected AppendicitisRecruitingNCT07496723
• TACTILE : Validation of a Teleconsultation-Based Predictive Score for the Diagnosis of Acute Appendicitis in Children Using Artificial Intelligence MethodsNot yet recruitingNCT07479849Not applicable
• Clinical Study of PEG Bowel Preparation in Appendectomy PatientsRecruitingNCT07478029
• First Appendectomy Using Revolve Surgical Robotic ArmNot yet recruitingNCT07455487Not applicable
• Direct Visualization ERAT Versus Laparoscopic Appendectomy in Adults With Acute Uncomplicated AppendicitisRecruitingNCT07230379Not applicable
• Comparison Between Metallic Clip Ligation and Suture Ligation of Appendicular Stump in Laparoscopic AppendectomyNot yet recruitingNCT07129746Not applicable
• Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump ClosureRecruitingNCT07115303Not applicable
• Early vs Conventional Enteral Nutrition After Uncomplicated Paediatric Open AppendectomyRecruitingNCT07016919Not applicable
• Prostaglandin-E Urinary Metabolite (PGE-M) as a Predictor of Acute Appendicitis in ChildrenRecruitingNCT07008092
• Enhanced Recovery After Surgery (ERAS) for Complicated AppendicitisRecruitingNCT06948071Not applicable
• Comparison of Outcome of Open Appendectomy With and Without Transversus Abdominis Plane (TAP) BlockNot yet recruitingNCT06943456Not applicable
• Risk Factors of Failure of Conservative Treatment in Acute Non Complicated AppendicitisNot yet recruitingNCT06828952
• Prevention of Postoperative Hernias in Emergency SurgeryRecruitingNCT06815822
• A Global Prospective Cohort Study on Outcomes of Appendicectomy for AppendicitisRecruitingNCT06774001
• Textbook Outcomes in Urgent AppendectomyNot yet recruitingNCT06765044
• The Impact of a Diagnostic Strategy for Acute Appendicitis in Children With Acute Abdominal Pain in Primary CareRecruitingNCT06762275Not applicable
• APPI-Cost Trial for Perforated AppendicitisRecruitingNCT06705842Phase 4
• Artificial Intelligence-driven Virtual Standardized Pediatric Patients TrialRecruitingNCT06699433Not applicable
• Laparoscopic Versus Open Appendectomy Plus Peritoneal Lavage for Acute Complicated Appendicitis Patients With Diffuse PeritonitisNot yet recruitingNCT06633744
• Magnesium Sulfate in Children Undergoing Laparoscopic AppendectomyRecruitingNCT06563349Phase 4
• Appendicoliths in Acute Complicated Appendicitis Patients With AbscessNot yet recruitingNCT06469086
• Early Detection of Infection Using the Fitbit in Pediatric Surgical PatientsRecruitingNCT06395636Not applicable
• Oral Antibiotic Outpatient Therapy vs. Placebo in the Treatment of Uncomplicated Acute AppendicitisNot yet recruitingNCT06210269Not applicable
• Transumbilical Laparoscopic AppendectomyRecruitingNCT06177418Not applicable
• IA Model for Acute Appendicitis in CTRecruitingNCT06175169Not applicable
• Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal PainRecruitingNCT06160778Phase 3
• New Diagnostic Markers In Dignosis Of Complicated AppendixRecruitingNCT06102239Not applicable
• Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected AppendicitisRecruitingNCT06083064Not applicable
• Clinical Trial for a Outpatient Clinical Management for Complicated Acute AppendicitisNot yet recruitingNCT06059365Not applicable
• Diagnostic Importance of the C-reactive Protein From Blood and Saliva in Children With Acute AppendicitisNot yet recruitingNCT06051825
• Intestinal Flora and Metabonomics of AppendicitisRecruitingNCT06035029
• Benefit of Hypnosis on Smartphone for Acute Post-operative Pain (HYPNO-APP)RecruitingNCT05854914Not applicable
• Radiomic Modeling in Differentiating Uncomplicated From Complicated Acute AppendicitisRecruitingNCT05843630
• Peri-operative Analgesia for Single-incision Laparoscopic AppendectomyNot yet recruitingNCT05773521
• Fast Track Therapeutic Model in Acute Complicated Appendicitis in PediatricsRecruitingNCT05761080Phase 4
• Same Day Ambulatory Appendectomy (SAMBA)RecruitingNCT05691348Not applicable
• Laparoscopic Versus Open Appendectomy Prospective Randomized Control StudyNot yet recruitingNCT05611489Not applicable
• Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)Not yet recruitingNCT05473325
• Appendectomy vs. Symptomatic Treatment in Uncomplicated Acute Appendicitis Among Pediatric PatientsRecruitingNCT05289713Not applicable
• Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy, Peritoneal Irrigation During Laparoscopic Appendectomy Does the Grade of Contamination Matter?RecruitingNCT05075252
• The Prevalence of Appendiceal Tumours in Periappendicular AbscessNot yet recruitingNCT04634448Not applicable
• Povidone-iodine Irrigation for Prevention of Intra-abdominal Abscess in Pediatric Perforated Appendicitis: a Multi-center Stepped Wedge Cluster Randomized StudyNot yet recruitingNCT04200729Phase 4
• Operative Versus Non-Operative Management for Appendicitis With Abscess or PhlegmonRecruitingNCT04168866Not applicable
• The Value of Post-operative Antibiotic Therapy After Laparoscopic Appendectomy for Complicated Acute Appendicitis (Other Than for Generalized Peritonitis)RecruitingNCT03688295Phase 3
• Web-based International Register of Emergency Surgery and TraumaRecruitingNCT03643718
• Acute Appendicitis and Microbiota - Etiology of Appendicitis and Antibiotic Therapy EffectsEnrolling by invitationNCT03257423Not applicable
• Antibiotics vs. Placebo in Acute Uncomplicated AppendicitisEnrolling by invitationNCT03234296Not applicable
• Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill PatientsCompletedNCT06901544Results posted
• Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSFTerminatedNCT05966454Phase 4Results posted
• Antibiotic Instillation in AppendicitisCompletedNCT05470517Phase 2Results posted
• Sugammadex vs Neostigmine Reversal in Pediatric AppendectomyTerminatedNCT05256901Phase 4Results posted
• Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive PatientsTerminatedNCT04748120Not applicableResults posted
• Probiotics and Antibiotic Associated Diarrhea in Pediatric Complicated AppendicitisCompletedNCT04529980Not applicableResults posted
• Antibiotic Duration in Post-appendectomy AbscessTerminatedNCT03795194Phase 4Results posted
• The Role of Contrast Enhanced Ultrasound in AppendicitisCompletedNCT03687502Phase 2Results posted
• Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated AppendicitisCompletedNCT03289351Phase 4Results posted
• Optimal Care of Complicated AppendicitisCompletedNCT03159754Phase 4Results posted
• Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in ChildrenCompletedNCT02991937Phase 4Results posted
• Influence of the Different Ways of Appendix Stump Closure on Patient Outcome in Laparoscopic AppendectomyCompletedNCT02941640Not applicableResults posted
• The Impact of IV Acetaminophen on Pain After Appendectomy for Perforated AppendicitisCompletedNCT02881996Not applicableResults posted
• The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) TrialCompletedNCT02800785Not applicableResults posted
• Efficacy and Safety Study of Eravacycline Compared With Meropenem in Complicated Intra-abdominal InfectionsCompletedNCT02784704Phase 3Results posted
• Role of Intravenous Versus Home Oral Antibiotics in Perforated AppendicitisCompletedNCT02724410Not applicableResults posted
• Effect of Peri-operative Supplemental Oxygen in Wound Infection After AppendectomyCompletedNCT02687217Not applicableResults posted
• Dilute Povidone-iodine Irrigation vs No Irrigation for Children With Acute, Perforated AppendicitisCompletedNCT02664220Phase 2Results posted
• EHR-based Decision Support for Pediatric Acute Abdominal Pain in Emergency CareCompletedNCT02633735Not applicableResults posted
• Non-operative Management of Pediatric Appendicitis With an AppendicoltihTerminatedNCT02189668Not applicableResults posted
• Fast Track Appendectomy for Suppurative AppendicitisCompletedNCT02137603Not applicableResults posted
• Randomized Controlled Trial of a Patient Activation Tool in Pediatric Appendicitis (Antibiotics Alone vs. Appendectomy)CompletedNCT02110485Not applicableResults posted
• Low vs. Standard Dose CT for Appendicitis TrialCompletedNCT01925014Not applicableResults posted
• Laparoscopic Versus Open Appendectomy? Let the Patient DecideCompletedNCT01738750Not applicableResults posted
• Transversus Abdominis Plane (TAP) Versus Local Anesthetic for Lap AppendectomiesTerminatedNCT01575028Phase 2Results posted
• A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal InfectionsTerminatedNCT01110382Phase 3Results posted
• Appendicectomy Versus Antibiotics in the Treatment of Acute Uncomplicated AppendicitisActive, not recruitingNCT01022567Not applicableResults posted
• Single-incision Laparoscopic (SILS) Versus Conventional Laparoscopic Appendectomy for the Treatment of Acute AppendicitisTerminatedNCT00997516Not applicableResults posted
• Diagnosis of Acute Appendicitis: Low-dose Computed Tomography (CT) Versus Standard-dose CTCompletedNCT00913380Phase 3Results posted
• Magnetic Resonance Imaging (MRI) of Appendicitis in ChildrenCompletedNCT00723788Not applicableResults posted
• Intravenous Versus Intravenous/Oral Antibiotics for Perforated AppendicitisCompletedNCT00462020Not applicableResults posted
• Wound Infection Alexis Wound RetractorCompletedNCT00323453Not applicableResults posted
• Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI)CompletedNCT00230971Phase 4Results posted

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