Appendicitis clinical trials
The registry lists 409 studies for Appendicitis across more than 10 countries. 61 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 245
- Status unknown
- 55
- Recruiting
- 36
- Not yet recruiting
- 23
- Terminated
- 19
- Active, not recruiting
- 14
Phase
- Phase 4
- 31
- Phase 3
- 20
- Phase 2
- 18
- Phase 1
- 6
- Early Phase 1
- 2
Where
- United States
- 78
- Turkey
- 23
- Egypt
- 20
- Finland
- 17
- China
- 17
- France
- 15
Who runs them
Assiut University (8) · Children's Mercy Hospital Kansas City (8) · Turku University Hospital (8) · Mansoura University (5) · Helsinki University Central Hospital (5) · Zagazig University (5) · Cirujanos la Serena (4) · University of Washington (4)
Studies
Recruiting first, then most recently updated. Showing 50 of 409 — search for more.
- Immediate Laparoscopic Appendectomy Versus Interval Laparoscopic Appendectomy for Early Appendicular MassNot yet recruitingNCT07837531Not applicable
- Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected AppendicitisRecruitingNCT06083064Not applicable1 country
- Perforated Appendicitis and Postoperative Antibiotics Pilot TrialNot yet recruitingNCT07656636Not applicable
- Effect Of Specimen Extraction Site And Local Anesthesia On Postoperative Pain In Laparoscopic AppendectomyRecruitingNCT07824908Not applicable1 country
- Laparoscopic vs Open Appendectomy in Obese PatientsNot yet recruitingNCT07822503Not applicable
- Direct Visualization ERAT Versus Laparoscopic Appendectomy in Adults With Acute Uncomplicated AppendicitisRecruitingNCT07230379Not applicable1 country
- Video-Based Grading of Intraoperative Adverse Events in Pediatric Laparoscopic AppendectomyRecruitingNCT077946181 country
- Magnesium Sulfate in Children Undergoing Laparoscopic AppendectomyRecruitingNCT06563349Phase 41 country
- Feasibility and Safety of a Pediatric ERAS Protocol for Laparoscopic AppendectomyRecruitingNCT07643285Not applicable1 country
- Laparoscopic Appendectomy: Outcomes of 10 mmHg Versus 15 mmHg Intra-abdominal PressureNot yet recruitingNCT07727499Not applicable1 country
- The Impact of a Diagnostic Strategy for Acute Appendicitis in Children With Acute Abdominal Pain in Primary CareRecruitingNCT06762275Not applicable1 country
- Primary Versus Delayed Wound Closure in Complicated Appendectomy (The HIEDI-Yemen Trial)Not yet recruitingNCT07688109Not applicable1 country
- Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic AppendectomyRecruitingNCT07678086Not applicable1 country
- Effects of Cartoons and Mobile Games on Preoperative Anxiety and Fear in Children With Appendicitis: An RCTRecruitingNCT07640230Not applicable1 country
- Early Detection of Infection Using the Fitbit in Pediatric Surgical PatientsRecruitingNCT06395636Not applicable1 country
- Diagnosis of Abdominal Pain Using RNA Levels: The NATURAL StudyRecruitingNCT075793121 country
- Out-patiente Management for Gangrenous Acute Appendicitis: The PENDI-CSI II Randomized Clinical Trial.RecruitingNCT07521969Not applicable1 country
- Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy, Peritoneal Irrigation During Laparoscopic Appendectomy Does the Grade of Contamination Matter?RecruitingNCT050752521 country
- Comparison of Diagnostic Methods in Patients Operated for Suspected AppendicitisRecruitingNCT074967231 country
- Same Day Ambulatory Appendectomy (SAMBA)RecruitingNCT05691348Not applicable2 countries
- TACTILE : Validation of a Teleconsultation-Based Predictive Score for the Diagnosis of Acute Appendicitis in Children Using Artificial Intelligence MethodsNot yet recruitingNCT07479849Not applicable1 country
- Clinical Study of PEG Bowel Preparation in Appendectomy PatientsRecruitingNCT074780291 country
- First Appendectomy Using Revolve Surgical Robotic ArmNot yet recruitingNCT07455487Not applicable
- APPI-Cost Trial for Perforated AppendicitisRecruitingNCT06705842Phase 41 country
- Operative Versus Non-Operative Management for Appendicitis With Abscess or PhlegmonRecruitingNCT04168866Not applicable1 country
- Comparison Between Metallic Clip Ligation and Suture Ligation of Appendicular Stump in Laparoscopic AppendectomyNot yet recruitingNCT07129746Not applicable1 country
- Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump ClosureRecruitingNCT07115303Not applicable1 country
- PAINED: Project Addressing INequities in the Emergency DepartmentRecruitingNCT05488080Not applicable1 country
- Prevention of Postoperative Hernias in Emergency SurgeryRecruitingNCT068158221 country
- Early vs Conventional Enteral Nutrition After Uncomplicated Paediatric Open AppendectomyRecruitingNCT07016919Not applicable1 country
- Prostaglandin-E Urinary Metabolite (PGE-M) as a Predictor of Acute Appendicitis in ChildrenRecruitingNCT070080921 country
- Comparison of Outcome of Open Appendectomy With and Without Transversus Abdominis Plane (TAP) BlockNot yet recruitingNCT06943456Not applicable
- Enhanced Recovery After Surgery (ERAS) for Complicated AppendicitisRecruitingNCT06948071Not applicable1 country
- A Global Prospective Cohort Study on Outcomes of Appendicectomy for AppendicitisRecruitingNCT067740017 countries
- Laparoscopic Antibiotic Lavage to Prevent Intra-abdominal Abscess Formation in Complicated AppendicitisNot yet recruitingNCT06841003Phase 3
- Risk Factors of Failure of Conservative Treatment in Acute Non Complicated AppendicitisNot yet recruitingNCT068289521 country
- Povidone-iodine Irrigation for Prevention of Intra-abdominal Abscess in Pediatric Perforated Appendicitis: a Multi-center Stepped Wedge Cluster Randomized StudyNot yet recruitingNCT04200729Phase 41 country
- Textbook Outcomes in Urgent AppendectomyNot yet recruitingNCT06765044
- Artificial Intelligence-driven Virtual Standardized Pediatric Patients TrialRecruitingNCT06699433Not applicable1 country
- Laparoscopic Versus Open Appendectomy Plus Peritoneal Lavage for Acute Complicated Appendicitis Patients With Diffuse PeritonitisNot yet recruitingNCT06633744
- Transumbilical Laparoscopic AppendectomyRecruitingNCT06177418Not applicable1 country
- Peri-appendiceal Abscess and Phlegmon in Acute Complicated Appendicitis PatientsNot yet recruitingNCT06490185
- Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal PainRecruitingNCT06160778Phase 31 country
- Appendicoliths in Acute Complicated Appendicitis Patients With AbscessNot yet recruitingNCT06469086
- A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic AppendicitisRecruitingNCT06304285Not applicable1 country
- Oral Antibiotic Outpatient Therapy vs. Placebo in the Treatment of Uncomplicated Acute AppendicitisNot yet recruitingNCT06210269Not applicable1 country
- IA Model for Acute Appendicitis in CTRecruitingNCT06175169Not applicable1 country
- New Diagnostic Markers In Dignosis Of Complicated AppendixRecruitingNCT06102239Not applicable1 country
- Clinical Trial for a Outpatient Clinical Management for Complicated Acute AppendicitisNot yet recruitingNCT06059365Not applicable
- Appendectomy vs. Symptomatic Treatment in Uncomplicated Acute Appendicitis Among Pediatric PatientsRecruitingNCT05289713Not applicable1 country