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RecruitingNCT06102239Updated Oct 26, 2023

New Diagnostic Markers In Dignosis Of Complicated Appendix

An interventional study of Bilirubin level sodium level c reactive protein level in Complicated Appendicitis, sponsored by Sohag University. Recruiting at 1 site in Egypt. Open to participants aged 10 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-10-26.

Sponsored by Sohag University · Not applicable, Interventional, and Diagnostic

From the registry’s dates

  • Primary completion was expected by Mar 2024, 2 years 7 months ago, but the record still lists the study as recruiting.
  • Started Oct 2023; still recruiting 3 years 1 month later.
Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Not applicable
Ages
10 Years to 40 Years
Sex
All
01

Study summary

Most common cause of acute abdomen is acute appendicitis delay dignosis of acute appendicitis lead to complications as perforation this study examined efficacy of hyperbilirubinemia\&hyponatremia as indicator of complicated appendicitis

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Conditions studied

  • Complicated Appendicitis

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03

In context

Appendicitis

419 studies on the registry are indexed under Appendicitis; 67 are open to participants now.

This study's planned enrollment of 50 is below the median of 111 across 252 interventional studies indexed under Appendicitis.

Browse Appendicitis studies →

Lead sponsor

Sohag University is the lead sponsor of 1,230 studies on the registry; 636 are open to participants now.

Browse Sohag University studies →

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
10 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • all patient admitted for acute appendicitis underwent surgery and post operativly confirmed histopathology of acute appendicitis

Exclusion criteria

Exclusion Criteria:

  • patient with liver disease Liver transplantation Chronic alcoholism Congental biliary disease Pregnancy Appendicular neoplasm Hemolytic disease Hepatocellular carcinoma
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Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
50 participants (estimated)

Interventions

  • Diagnostic testBilirubin level sodium level c reactive protein level

    detect level of bilirubin,sodium \&c-reactive protein as indicator of complicated appendicitis

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What researchers measure

Primary outcomes

  1. Level of bilirubin in acute appendicitis

    Time frame: 6 months

  2. Level of sodium in acute appendicitis

    Time frame: 6 months

  3. Level of c-reactive proteins in acute appendicitis

    Time frame: 6 months

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Study locations

1 of 1 sites recruiting
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References and documents

Publications

  • Virmani S, Prabhu PS, Sundeep PT, Kumar V. Role of laboratory markers in predicting severity of acute appendicitis. Afr J Paediatr Surg. 2018 Jan-Mar;15(1):1-4. doi: 10.4103/ajps.AJPS_47_16. PubMed 30829300 ↗
  • Kar S, Behera TK, Jena K, Sahoo AK. Hyperbilirubinemia as a Possible Predictor of Appendiceal Perforation in Acute Appendicitis: A Prospective Study. Cureus. 2022 Feb 2;14(2):e21851. doi: 10.7759/cureus.21851. eCollection 2022 Feb. PubMed 35282512 ↗
  • Alvarado A. A practical score for the early diagnosis of acute appendicitis. Ann Emerg Med. 1986 May;15(5):557-64. doi: 10.1016/s0196-0644(86)80993-3. PubMed 3963537 ↗
  • Kanumba ES, Mabula JB, Rambau P, Chalya PL. Modified Alvarado Scoring System as a diagnostic tool for acute appendicitis at Bugando Medical Centre, Mwanza, Tanzania. BMC Surg. 2011 Feb 17;11:4. doi: 10.1186/1471-2482-11-4. PubMed 21329493 ↗

Individual participant data

Plan to share: Undecided

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 26, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06102239
Lead sponsor
Sohag University
Responsible party
Amr Mohamed Amin (Residiant in general surgery department, Sohag University) — Principal investigator
First posted
Oct 26, 2023
Start date
Oct 1, 2023
Primary completion
Mar 31, 2024 (estimated)
Completion
Mar 31, 2024 (estimated)
Last update
Oct 26, 2023

Study contacts

Amr M Amin, Residents
Contact
amr_mohamed_post@med.sohag.edu.eg
01113486740
Omar A Syed, Professor
Contact

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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