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Aphasia clinical trials

The registry lists 338 studies for Aphasia across more than 10 countries. 95 are recruiting or about to start. 209 of them are mainly about Aphasia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 3 narrower conditions too, such as Aphasia, Primary Progressive: 411 studies, 121 open.

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Status

Completed
181
Recruiting
68
Status unknown
32
Not yet recruiting
19
Terminated
14
Active, not recruiting
12

Phase

Phase 2
25
Phase 3
9
Phase 1
8
Phase 4
6
Early Phase 1
2

Where

United States
175
United Kingdom
19
Germany
17
China
15
France
15
Canada
9

Who runs them

VA Office of Research and Development (15) · Shirley Ryan AbilityLab (10) · Johns Hopkins University (8) · University of Pennsylvania (8) · Medical College of Wisconsin (8) · Changping Laboratory (8) · University of Chicago (6) · US Department of Veterans Affairs (5)

What is being tested here

Drugs under test in Aphasia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Escitalopram101
Flortaucipir101
Levodopa013
Donepezil012
Pittsburgh compound B002
Memantine002
VX-745001
Rotigotine001
Methylprednisolone011
Benserazide001

Drug classes tested here Cholinesterase inhibitors 3

Coming up

2phase 3 studies under way
28studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest

Who these studies take

Of the 68 Aphasia studies recruiting now, 31 (46%) set no upper age limit and 11 (16%) stop at 75 or younger. 1 (1%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 17 (25%) take healthy volunteers.

Recruiting studies that take each age, of 68
AgeWomenMen
101 (1%)1 (1%)
1846 (68%)46 (68%)
3057 (84%)57 (84%)
4068 (100%)68 (100%)
5068 (100%)68 (100%)
6567 (99%)67 (99%)
7566 (97%)66 (97%)
8546 (68%)46 (68%)

Across all 338 studies, recruiting or not: 12% stop at 75 or younger and 2% at 65; 6% take children; 0% are for women only and 0% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Aphasia studies take

Of 185 interventional studies with no phase under Aphasia, half reached primary completion within 36 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase36 mo20–57 · 185 studies—36 mo19–57 · 183 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting2

Results posted2

Newly registered5

Studies

Recruiting first, then most recently updated. Showing 50 of 338. Browse all 338 → or search them.