An interventional study of taVNS and sham taVNS in Aphasia and Apraxia of Speech, sponsored by University of Florida. Enrolling by invitation at 1 site in United States. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-05-04.
Sponsored by University of Florida · Not applicable, Interventional, and Treatment
The goal of this research study is to evaluate a novel approach to improving speech recovery in those with acquired apraxia of speech. We will enroll participants with apraxia of speech resulting from stroke or brain injury to complete several tasks and intervention. Testing will take place four times over the course of the study and intervention will take place 5 days a week for 16 weeks. Overall, you can expect to spend up to 17 weeks participating in this study.
338 studies on the registry are indexed under Aphasia; 95 are open to participants now.
This study's planned enrollment of 12 is below the median of 30 across 298 interventional studies indexed under Aphasia.
Browse Aphasia studies →University of Florida is the lead sponsor of 1,287 studies on the registry; 199 are open to participants now.
Of its 180 completed or terminated interventional studies of FDA-regulated products, 143 (79%) have results posted.
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Exclusion Criteria:
non-invasive vagus nerve stimulation is administered alongside standard intervention
Device: taVNS
sham stimulation is administered alongside standard intervention
Device: sham taVNS
active vagus nerve stimulation
sham vagus nerve stimulation
Adverse events
Frequency and severity of adverse events will be monitored and evaluated for severity and impact on attrition.
Time frame: 6 months
Compliance
Percentage of the population that remains engaged in the study and completes all stimulation sessions.
Time frame: 6 months
Change in speech production scores
Primary outcomes for this aim include the learning trajectory over 8 weeks of speech therapy as measured by weekly probes and the WAB when intervention is combined with taVNS versus control stimulation to determine the effect of taVNS on re-learning motor speech plans and the trajectory of motor speech recovery.
Time frame: 6 months
Plan to share: No
No publications or documents are linked to this record.
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