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RecruitingNCT06365658Updated Aug 26, 2026

Cognitive Functioning in Adults With Somatic Diseases and General Population From a Biopsychosocial Perspective

An observational study in Aphasia, Development, Human and Neuropathology, sponsored by Bartosz M. Radtke. Recruiting at 1 site in Poland. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-26.

Sponsored by Bartosz M. Radtke · Observational

From the registry’s dates

  • Started Jul 2023; still recruiting 3 years 4 months later.
Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
600
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this observational study is to investigate cognitive functioning profiles in adults with neurologically recognized aphasic syndromes and general population.

The study group consist of minimal 600 adults (over 18 y.o.) who will be examined by qualified diagnosticians. Participants will be evaluated with tasks related to the studied variables: memory, learning and language. Furthermore informations regarding past and present health condition will be collected from participants.

The main questions it aims to answer are:

  1. What is the profile of memory and learning among polish adults?
  2. Do gender and age moderates patterns of memory and learning functioning among polish adults?
  3. What is a specific pattern of language functioning in adults with neurologically recognized aphasic syndromes?
  4. Do gender moderates specific patterns of language functioning in adults with neurologically recognized aphasic syndromes?

Researchers will compare the following groups of adults:

  1. general population/control group
  2. with neurologically recognized aphasic syndromes
  3. seniors (over 60 y.o.)
02

Conditions studied

  • Aphasia
  • Development, Human
  • Neuropathology

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Keywords

  • aphasia
  • memory
  • learning
  • language
  • adults
  • seniors
03

In context

Aphasia

338 studies on the registry are indexed under Aphasia; 95 are open to participants now.

This study's planned enrollment of 600 is above the median of 77 across 36 observational studies indexed under Aphasia.

Browse Aphasia studies →

Lead sponsor

Bartosz M. Radtke is the lead sponsor of 4 studies on the registry; 3 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Polish adults.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria for general population/control group:

  • age from 18 to 60 y.o.

Inclusion criteria for neurologically recognized aphasic syndromes

  • age above 18 y.o.
  • neurologically recognized aphasic syndromes

Inclusion criteria

Inclusion criteria for seniors:

  • age above 60 y.o.

Exclusion criteria for general population/control group:

  • age less then 18 y.o.
  • neurologically recognized aphasic syndromes

Exclusion criteria for neurologically recognized aphasic syndromes

  • age less then 18 y.o.
  • no neurologically recognized aphasic syndromes

Exclusion criteria

Exclusion criteria for seniors

  • age less then 60 y.o.
  • diseases of the nervous system, such as: stroke, craniocerebral trauma, neuroinfections, neurodegenerative diseases
  • mental disorders such as depression, psychotic disorders, anxiety disorders, addictions
05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
600 participants (estimated)
Patient registry
No

Groups and cohorts

  • General population/control group

    Polish adults (age 18 to 60 y.o).

    Diagnostic Test: Psychological assessment

  • Neurologically recognized aphasic syndromes

    Polish adults (age 18 to 60 y.o) with neurologically recognized aphasic syndromes.

    Diagnostic Test: Psychological assessment

  • Seniors (over 60 y.o)

    Polish adults (over 60 y.o.)

    Diagnostic Test: Psychological assessment

Interventions

  • Diagnostic testPsychological assessment

    Psychological assessment of memory, learning and language

06

What researchers measure

Primary outcomes

  1. Memory and learning

    Test of Memory and Learning (second edition). A standardized test measuring memory functioning and learning abilities. The test includes four basic factors (Verbal Memory, Nonverbal Memory, Complex Memory, and Delayed Recall) and five supplementary factors (Attention/Concentration, Sequential Memory, Free Recall, Associative Recall and Learning). The raw scores obtained in each tested subscale are converted into scores scaled based on age norms, ranging from 1 to 20, where a higher score means better functioning of the examined area, and a lower result means poorer functioning.

    Time frame: July 3, 2023 until June 30, 2026

  2. Language

    Boston Diagnostic Aphasia Examination-Third Edition. A spectrum of tools that helps to identify and distinguish among disorders of language function and neurologically recognized aphasic syndromes. The test have five functional subsections: 1) Conversational and Expository Speech, 2) Auditory Comprehension, 3) Oral Expression, 4) Reading and 5) Writing. The raw scores obtained in each tested subscale are converted into a percentile scale, ranging from 1 to 100, where a higher score means better functioning of the examined area, and a lower result means poorer functioning.

    Time frame: July 3, 2023 until June 30, 2026

  3. Socio-demographic data

    Author's survey of socio-demographic data, including: gender, month and year of birth, region of residence

    Time frame: July 3, 2023 until June 30, 2026

Secondary outcomes

  1. General mental state

    Mini-Mental State Examination. A clinical scale used to examine disorders in a patient's cognitive functioning. The questionnaire consists a series of questions allowing the assessment of the following functions: 1) orientation in time and place, 2) attention/concentration, 3) short-term memory (recall), 4) language skills, 5) visual-spatial abilities, 6) ability to understand and follow the instructions. The maximum score that can be obtained on the test is 30 points. 27-30 is a correct result; 24-26 is a cognitive impairment without dementia; 19-23 mean mild dementia; 11-18 is a moderate degree dementia and 0-10 mean profound dementia.

    Time frame: July 3, 2023 until June 30, 2026

  2. Health related data

    Author's survey of health related data, including: hearing, eyesight, hypertension, atherosclerosis, previous heart attack, diabetes, endocrine diseases, respiratory system diseases, musculoskeletal system diseases, nervous system diseases, kidney diseases, sleep disorders, hospitalizations, procedures under general anesthesia, cancer, medications.

    Time frame: July 3, 2023 until June 30, 2026

  3. Education data

    Author's survey of education, including: years of education, level of education, occupation, level of education of the participant's parents.

    Time frame: July 3, 2023 until June 30, 2026

07

Study locations

1 of 1 sites recruiting
  • Laboratory of Psychological and Educational Tests
    Gdansk, Pomeranian Voivodeship 80-239, Poland
    Recruiting
    • Rafał Nowicki, M.A. · Contactnowicki@pracowniatestow.pl · +48509805591
    • Urszula Sajewicz-Radtke, Ph.D. · Principal investigator
    • Bartosz M Radtke, Ph.D. · Principal investigator
    • Ariadna Łada-Maśko, Ph.D. · Principal investigator
    • Beata Daniluk, Ph.D. · Sub investigator
    • Piotr Markiewicz, Ph.D. · Sub investigator
    • Paweł Jurek, Ph.D. · Sub investigator
    • Michał Olech, Ph.D. · Sub investigator
    • Artur Sawicki, M.A. · Sub investigator
    • Rafał Nowicki, M.A. · Sub investigator
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 26, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06365658
Lead sponsor
Bartosz M. Radtke
Responsible party
Bartosz M. Radtke (CEO, Laboratory of Psychological and Educational Tests) — Sponsor-investigator
First posted
Apr 15, 2024
Start date
Jul 3, 2023
Primary completion
Jun 30, 2026
Completion
Dec 2026 (estimated)
Last update
Aug 26, 2026

Study contacts

Rafał Nowicki, M.A.
Contact
nowicki@pracowniatestow.pl
+48509805591
Urszula Sajewicz-Radtke, Ph.D.
study director · Laboratory of Psychological and Educational Tests
Bartosz M Radtke, Ph.D.
principal investigator · Laboratory of Psychological and Educational Tests
Ariadna Łada-Maśko, Ph.D.
principal investigator · Laboratory of Psychological and Educational Tests

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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