Aphasia, Broca clinical trials
The registry lists 35 studies for Aphasia, Broca across 9 countries. 11 are recruiting or about to start. 20 of them are mainly about Aphasia, Broca (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Who runs them
Mayo Clinic (3) · University of South Carolina (2) · University of Calgary (2) · Shirley Ryan AbilityLab (2) · University of Minnesota (2) · University of California, Berkeley (2) · Leigh R. Hochberg, MD, PhD. (1) · Pace University (1)
What is being tested here
Drugs under test in Aphasia, Broca studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Dec 2026Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST) · Teachers College, Columbia University
- Dec 2026Mirror Speech Entrainment: A Novel Technique for Voice Personalized Speech Entrainment for Nonfluent Aphasia · University of South Florida
- Jul 2027The Neurobiology of Two Distinct Types of Progressive Apraxia of Speech · Mayo Clinic
Who these studies take
Of the 8 Aphasia, Broca studies recruiting now, 2 (25%) set no upper age limit and 2 (25%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 6 (75%) | 6 (75%) |
| 30 | 7 (88%) | 7 (88%) |
| 40 | 7 (88%) | 7 (88%) |
| 50 | 7 (88%) | 7 (88%) |
| 65 | 8 (100%) | 8 (100%) |
| 75 | 8 (100%) | 8 (100%) |
| 85 | 4 (50%) | 4 (50%) |
Across all 35 studies, recruiting or not: 20% stop at 75 or younger and 9% at 65; 9% take children; 0% are for women only and 0% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Aphasia, Broca studies take
Of 18 interventional studies with no phase under Aphasia, Broca, half reached primary completion within 21 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 21 mo7–57 · 18 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 35 of 35. search them.
- BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Aphasia (BG-Aphasia-01)Not yet recruitingNCT07791459Not applicable
- Music Therapy for Rehabilitation in Post-stroke Non-fluent Aphasia: the Indian AdaptationRecruitingNCT06323330Not applicable1 country
- Sensory-Motor Integration for Speech Rehabilitation in Patients With Post-stroke AphasiaRecruitingNCT04433351Not applicable1 country
- Combined Intervention Program for Non-fluent Aphasia Based on NeuroplasticityNot yet recruitingNCT07759375Not applicable
- Superiority Trial of Aphasia-focused Rehabilitation With tDCS StimulationRecruitingNCT07688551Phase 2/31 country
- Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)RecruitingNCT07036406Phase 21 country
- The Neurobiology of Two Distinct Types of Progressive Apraxia of SpeechRecruitingNCT033130111 country
- Effects of Neuronavigated Theta Burst Stimulation in Therapy of Post-stroke AphasiaRecruitingNCT05303649Not applicable1 country
- Aphasia Physical EXercise Study: Randomized TrialRecruitingNCT07281313Not applicable1 country
- Longitudinal Multi-Modality Imaging in Progressive Apraxia of SpeechRecruitingNCT01818661Phase 41 country
- High-frequency nrTMS on the Contralateral Broca Mirror Area for Glioma Patients With Early Postoperative AphasiaNot yet recruitingNCT05788445Not applicable
- Mirror Speech Entrainment: A Novel Technique for Voice Personalized Speech Entrainment for Nonfluent AphasiaActive, not recruitingNCT06829420Not applicable1 country
- Neurobiology of Language Recovery in Aphasia: Natural History and Treatment-Induced RecoveryCompletedNCT01927302Not applicable1 country
- Effects of PACE Technique in Patients With AphasiaCompletedNCT07521098Not applicable1 country
- Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke AphasiaCompletedNCT06185023Not applicable1 country
- Combining tDCS and CILT in Non-fluent AphasiaCompletedNCT05561400Not applicable1 country
- Speech Entrainment for Aphasia RecoveryCompletedNCT04364854Phase 21 country
- Home-Based Exercise in Primary Progressive Aphasia (HEPPA)CompletedNCT06181500Not applicable1 country
- Effectiveness of TDCS Over Broca's Area in Verb Naming: a Randomized, Double-Blind, Crossover StudyCompletedNCT06776978Not applicable1 country
- Repetitive Transcranial Magnetic Stimulation and Multi-modality Aphasia Therapy for Post-stroke Non-fluent AphasiaCompletedNCT04102228Not applicable1 country
- rTMS and Multi-Modality Aphasia Therapy for Post-Stroke AphasiaCompletedNCT04901156Not applicable1 country
- Transcranial Direct Stimulation (tDCS) and Behavioral Intervention in AphasiaCompletedNCT02226796Not applicable1 country
- Modeling Treated Recovery From AphasiaCompletedNCT03416738Not applicable1 country
- Neural Networks and Language Recovery in Aphasia From Stroke: fMRI StudiesCompletedNCT004671031 country
- Remote Neurobased Approach to Aphasia TherapyCompletedNCT05274360Not applicable1 country
- Transcranial Magnetic Stimulation in Nonfluent/Agrammatic Variant Primary Progressive AphasiaTerminatedNCT03153540Not applicable1 country
- Speech Hero Home Therapy for AphasiaCompletedNCT04471935Not applicable1 country
- Music After Stroke To Enhance RehabilitationStatus unknownNCT04441515Not applicable
- Development and Feasibility Analysis of Verbal Expressive Skills Management Programme (VESMP) for Patients With Broca AphasiaCompletedNCT03699605Not applicable1 country
- Virtual Reality Based Sensorimotor Speech TherapyCompletedNCT02928822Not applicable1 country
- Transcranial Direct Current Stimulation and Aphasia Language TherapyCompletedNCT01486654Phase 11 country
- PiB PET Scanning in Speech and Language Based DementiasCompletedNCT01623284Phase 11 country
- Effects of MTS-r on Speech Production in Non-fluent Aphasia Post-ischemic Stroke PatientsStatus unknownNCT02241213Phase 31 country
- Augmenting Language Therapy for Aphasia: LevodopaCompletedNCT01429077Phase 2/31 country
- Assessment of Cortical Stimulation Combined With Rehabilitation to Enhance Recovery in Broca's Aphasia.CompletedNCT00170703Phase 11 country