Drug

Donepezil clinical trials

Also written Aricept and E2020.

studies test it: 188
open now: 7
in phase 3: 31
first study started: 1999

Keep track of what changes. Save the Donepezil studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.

Watch these studies

How studies write it

Studies that test it under each name

Studies by the year they started

184 studies that test it; most in 2007 (18); 1 more planned to start later

Studies that test Donepezil, by start year
Year	Studies
1999	3
2000	2
2001	3
2002	7
2003	8
2004	7
2005	10
2006	10
2007	18
2008	16
2009	12
2010	5
2011	13
2012	8
2013	7
2014	10
2015	7
2016	7
2017	5
2018	5
2019	3
2020	4
2021	3
2022	3
2023	2
2024	2
2025	3
2026	1

By phase

A phase 1/2 study counts in both.

Early Phase 1: 5
Phase 1: 48
Phase 2: 44
Phase 3: 31
Phase 4: 49
No phase: 14

What it is tested for

Each study’s main condition, where its own words name it.

Alzheimer Disease: 55
Parkinson Disease: 14
Dementia: 14
Down Syndrome: 5
Cognitive Dysfunction: 4
Stroke: 4
Autistic Disorder: 4
Neuralgia: 4
Sleep Apnea, Obstructive: 3
Delirium: 3
Dementia, Vascular: 3
Schizophrenia: 3

Who runs them

Industry 86 · Other 102

Eisai Inc. (20) · Eisai Co., Ltd. (11) · Merck Sharp & Dohme LLC (6) · Corium, Inc. (6) · Pfizer (6) · Wake Forest University Health Sciences (5) · Eisai Korea Inc. (4) · Oregon Health and Science University (4)

Often tested with

Tested in the same studies.

Memantine (5) · Galantamine (5) · Venlafaxine (3) · Gabapentin (3) · Duloxetine (3) · Citalopram (2) · Vitamin E (2) · Modafinil (2)

Studies

Open first, then newest update. How each study uses Donepezil is read from its arms, and is right about nine times in ten.

Testing it · 188

See all 188 studies that test Donepezil →

Given in every arm · 24 — Donepezil is usual care beside what is tested

Showing 20 of 24.

As the comparator · 29 — what is tested is compared with Donepezil

Showing 20 of 29.

Codes

What other systems call Donepezil · ClinicalTrials.gg INT006678

MeSH (NLM) D000077265DonepezilConfirmed ClinicalTrials.gov, NLM, Wikidata
UNII (FDA) 8SSC91326PDONEPEZILConfirmed FDA, NLM, Wikidata
RxNorm 135447Confirmed FDA, Wikidata
Wikidata Q415081donepezilConfirmed FDA, NLM, Wikidata
NCI Thesaurus C66874DonepezilOne source FDA
DrugBank DB00843One source Wikidata

System	Code	Name there	Checked by
MeSH (NLM)	D000077265	Donepezil	Confirmed ClinicalTrials.gov, NLM, Wikidata
UNII (FDA)	8SSC91326P	DONEPEZIL	Confirmed FDA, NLM, Wikidata
RxNorm	135447	—	Confirmed FDA, Wikidata
Wikidata	Q415081	donepezil	Confirmed FDA, NLM, Wikidata
NCI Thesaurus	C66874	Donepezil	One source FDA
DrugBank	DB00843	—	One source Wikidata

Also registered as donepezil hydrochloride (UNII 3O2T2PJ89D · RxNorm 236559).

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.