Amblyopia clinical trials
The registry lists 189 studies for Amblyopia across more than 10 countries. 41 are recruiting or about to start. 175 of them are mainly about Amblyopia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Who runs them
Jaeb Center for Health Research (24) · Alaska Blind Child Discovery (6) · Retina Foundation of the Southwest (6) · Shahid Beheshti University of Medical Sciences (5) · Boston Children's Hospital (5) · National Eye Institute (NEI) (5) · Rebiscan, Inc. (5) · Universitat Politècnica de Catalunya (4)
What is being tested here
Drugs under test in Amblyopia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Ocular Characteristics in Patients With Craniosynostosis · Centre Hospitalier Universitaire, Amiens
- Dec 2026Evaluation of Echothiophate in Pediatric Patients With Refractory Amblyopia · University of Oklahoma
- Dec 2026A Study on the Efficacy and User Experience of Gamified Intervention for Children With Anisometropic Amblyopia · Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
- Dec 2026Binocular Amblyopia Treatment · Retina Foundation of the Southwest
- Dec 2026Clinical Data Registry of Amblyopia Patients on Luminopia Treatment · Luminopia
- Jan 2027Non-invasive Induction of Metaplasticity for Amblyopia · Boston Children's Hospital
- Jan 2027Video Treatment for Amblyopia · Retina Foundation of the Southwest
- Feb 2027OCT Eccentric Fixation and Amblyopia in Children · State University of New York College of Optometry
- Feb 2027Evaluation of AmblyoFix for the Treatment of Unilateral Amblyopia in Children · Eyesight Electronics
- Mar 2027Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy · The Cleveland Clinic
Who these studies take
Of the 30 Amblyopia studies recruiting now, 4 (13%) set no upper age limit and 24 (80%) stop at 75 or younger. 25 (83%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 7 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 21 (70%) | 21 (70%) |
| 18 | 14 (47%) | 14 (47%) |
| 30 | 13 (43%) | 13 (43%) |
| 40 | 11 (37%) | 11 (37%) |
| 50 | 9 (30%) | 9 (30%) |
| 65 | 7 (23%) | 7 (23%) |
| 75 | 6 (20%) | 6 (20%) |
| 85 | 6 (20%) | 6 (20%) |
Across all 189 studies, recruiting or not: 86% stop at 75 or younger and 85% at 65; 87% take children; 0% are for women only and 0% for men only; 27% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Amblyopia studies take
Of 71 interventional studies with no phase under Amblyopia, half reached primary completion within 33 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 33 mo17–47 · 71 studies | — | 34 mo21–72 · 58 studies |
| Observational | 10 mo3–22 · 16 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Stopped2
- Novel Amblyopia Treatment With Virtual Reality GamesTerminatedNov 6, 2026NCT06049459
- Access to EyeGlasses for School-aged ChildrenTerminatedOct 19, 2026NCT05588362
Newly registered1
- Psilocybin for Amblyopia - Targeting Critical Periods in HumansNov 5, 2026NCT07920081
Studies
Recruiting first, then most recently updated. Showing 50 of 189. Browse all 189 → or search them.
- Psilocybin for Amblyopia - Targeting Critical Periods in HumansRecruitingNCT07920081Phase 1/21 country
- Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of AgeRecruitingNCT06380517Phase 31 country
- Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of AgeRecruitingNCT06524882Phase 31 country
- OCT Eccentric Fixation and Amblyopia in ChildrenRecruitingNCT05714449Not applicable1 country
- Non-invasive Induction of Metaplasticity for AmblyopiaNot yet recruitingNCT07846397Not applicable
- Evaluation of AmblyoFix for the Treatment of Unilateral Amblyopia in ChildrenRecruitingNCT07323953Not applicable1 country
- Combining Noninvasive Brain Stimulation and Augmented Reality-based Dichoptic Therapy for Treating Amblyopic AdultsRecruitingNCT07752433Not applicable1 country
- Augmented Reality-Based Binocular Therapy for Visual Rehabilitation in Adults With AmblyopiaRecruitingNCT07819552Not applicable1 country
- Attention-based Binocular Training for Impaired Stereopsis (BRAVE)Not yet recruitingNCT07803458Not applicable1 country
- A Randomized Controlled Trial of Gabor-Based Perceptual Learning for Adult AmblyopiaRecruitingNCT07764198Not applicable1 country
- Valproate for the Treatment of Residual AmblyopiaRecruitingNCT07226141Phase 1/21 country
- A Study on the Efficacy and User Experience of Gamified Intervention for Children With Anisometropic AmblyopiaRecruitingNCT07472231Not applicable1 country
- Effectiveness of tDCS in Paediatric Amblyopia.RecruitingNCT07547670Not applicable1 country
- A Randomized Controlled Trial of Autostereoscopic 3D Vision Therapy for AmblyopiaNot yet recruitingNCT07709832Not applicable1 country
- Augmented Reality Training for Amblyopia After Congenital Cataract SurgeryNot yet recruitingNCT07693790Not applicable
- A Comparative Study of the Efficacy of AR Based Amblyopia Training Therapy and Occlusion Therapy in Older Children and Adults With AmblyopiaNot yet recruitingNCT07622576Not applicable1 country
- Binocular Visual Therapy and Video Games for Amblyopia Treatment.RecruitingNCT03655912Not applicable1 country
- 3D Movie Viewing vs Occlusion for Treating Amblyopia in ChildrenNot yet recruitingNCT07563946Not applicable
- Evaluation of Echothiophate in Pediatric Patients With Refractory AmblyopiaNot yet recruitingNCT07554131Phase 21 country
- Video Treatment for AmblyopiaRecruitingNCT05439200Not applicable1 country
- Visual Function Abnormalities in Strabismus and Amblyopia and Response to TherapyRecruitingNCT043102411 country
- Binocular Amblyopia TreatmentRecruitingNCT03288948Not applicable1 country
- Possible Beneficial Effects Of Combined Fluoxetine And Occlusion Therapy In Improving And Maintaining Vision In Amblyopia Using Optical Coherence Tomography Angiography (OCTA) And Visual Evoked Potential (VEP). The Aim Of The Study Is To Evaluate Possible Beneficial Effects For Different Age Groups.RecruitingNCT07417046Not applicable1 country
- Ocular Characteristics in Patients With CraniosynostosisRecruitingNCT069287271 country
- A Randomized Trial to Evaluate Sequential vs Simultaneous PatchingRecruitingNCT04378790Phase 31 country
- Patch-free Occlusion TherapyRecruitingNCT05440448Not applicable1 country
- VISION-3D: Visual Skills Improvement With On-screen 3D Movies.Not yet recruitingNCT07301645Not applicable
- Establishing New Treatment Approaches for Amblyopia: Perceptual Learning and Video GamesRecruitingNCT05522972Not applicable1 country
- Amblyopia Treatment for Children Aged 8 to 12 YearsRecruitingNCT07281742Not applicable1 country
- Clinical Data Registry of Amblyopia Patients on Luminopia TreatmentRecruitingNCT064292801 country
- Five-Year Visual Function and Refractive Outcomes After Congenital Cataract SurgeryRecruitingNCT070700371 country
- Early Detection and Prevention of Amblyopia and Visual Impairment Through Systematic Pediatric Vision ScreeningNot yet recruitingNCT071125601 country
- Interactive Binocular Treatment (I- BiT) in Adult Patients With Anisometropic AmblyopiaNot yet recruitingNCT07103473Not applicable1 country
- AR Training Versus Patching in Unilateral AmblyopiaRecruitingNCT06498206Not applicable1 country
- Clinical Treatment of Transcranial Direct Current Stimulation in Older Adolescents With AmblyopiaRecruitingNCT06760910Not applicable1 country
- Noninvasive Brain Stimulation in Adult AmblyopiaRecruitingNCT06712849Not applicable1 country
- Accommodation Response in Hypermetropic Anisometropia (ARIHA Study)RecruitingNCT06286410Not applicable1 country
- Developing Better Computerised Vision Tests (CVTV)RecruitingNCT062247511 country
- OKKO Space Academy to Check Children's Vision at HomeEnrolling by invitationNCT05313516Not applicable1 country
- New Pediatric Patching Method to Improve ComplianceRecruitingNCT02236351Not applicable1 country
- Plasma Biomarker in Amblyopia PatientsRecruitingNCT057057781 country
- Novel Amblyopia Treatment With Virtual Reality GamesTerminatedNCT06049459Not applicable1 country
- Evaluation of AmblyoFix for the Treatment of Unilateral AmblyopiaTerminatedNCT07240311Not applicable1 country
- Optical Correction and Visual Functions of Adults With AmblyopiaCompletedNCT05394987Not applicable2 countries
- Evaluation of Amblyopia Protocols Using a Dichoptic Gabor Videogame ProgramCompletedNCT06150391Not applicable1 country
- Access to EyeGlasses for School-aged ChildrenTerminatedNCT05588362Not applicable1 country
- Binocular iPad Sub-StudyActive, not recruitingNCT02365090Not applicable1 country
- Morning Versus Evening Patching in Childhood AmblyopiaCompletedNCT07294599Not applicable1 country
- Effect of Transcranial Magnetic Stimulation on Visual Functions of Adult Amblyopia: a Preliminary StudyActive, not recruitingNCT05393739Not applicable1 country
- Binocular Dig Rush Game Treatment for AmblyopiaCompletedNCT02983552Not applicable2 countries