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RecruitingNCT06928727COPACAUpdated Feb 12, 2026

Ocular Characteristics in Patients With Craniosynostosis

An observational study in Craniosynostosis, Strabismus and Intracranial Hypertension, sponsored by Centre Hospitalier Universitaire, Amiens. Recruiting at 1 site in France. Per ClinicalTrials.gov, last updated 2026-02-12.

Sponsored by Centre Hospitalier Universitaire, Amiens · Observational

From the registry’s dates

  • Started Apr 2025; still recruiting 1 year 7 months later.
Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
65
Sex
All
01

Study summary

Craniosynostosis are cranial deformations due to the premature closure of one or more cranial sutures. These deformations affect approximately one in 2.500 births. In most cases, craniosynostoses are isolated with unknown (non syndrome). On the other hand, 20% of these deformations are associated with other concentration (syndrome).

Craniosynostosis has morphological (associated dysmorphism) and functional (growth conflict between the skull and the brain) repercussions. Ophthalmological disorders are frequent: refractive disorders, oculomotor disorders, optic nerve damage, sensory damage.

This retrospective study aims to describe the ocular clinical characteristics associated with craniosynostosis in patients followed at the Amiens University Hospital.

02

Conditions studied

  • Craniosynostosis
  • Strabismus
  • Intracranial Hypertension
  • Amblyopia

Keywords

  • Craniosynostosis
  • strabismus
  • amblyopia
  • intracranial hypertension
03

In context

Craniosynostoses

51 studies on the registry are indexed under Craniosynostoses; 14 are open to participants now.

This study's planned enrollment of 65 is above the median of 43 across 26 observational studies indexed under Craniosynostoses.

Browse Craniosynostoses studies →

Lead sponsor

Centre Hospitalier Universitaire, Amiens is the lead sponsor of 586 studies on the registry; 185 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

patients with craniosynostosis followed at the Amiens University Hospital.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Diagnosis of craniostenosis

Exclusion criteria

Exclusion Criteria:

  • Posterior plagiocephalia
05

Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
65 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Rate of strabismus and amblyopia

    Rate of strabismus and amblyopia

    Time frame: 6 months

Secondary outcomes

  1. Rate of intracranial hypertension

    Rate of intracranial hypertension

    Time frame: 6 months

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 12, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06928727
Responsible party
Sponsor
First posted
Apr 15, 2025
Start date
Apr 4, 2025
Primary completion
Nov 2026 (estimated)
Completion
Nov 2026 (estimated)
Last update
Feb 12, 2026

Study contacts

Tran Thi Ha Chau, Pr
Contact
tran.chau@chu-amiens.fr
33+322089224

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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