Vision Disorders clinical trials
The registry lists 360 studies for Vision Disorders across more than 10 countries. 84 are recruiting or about to start. 129 of them are mainly about Vision Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 7 narrower conditions too, such as Amblyopia: 885 studies, 199 open.
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Status
Who runs them
Novartis Pharmaceuticals (32) · National Eye Institute (NEI) (7) · Kodiak Sciences Inc (7) · Laboratoires Thea (7) · Johnson & Johnson Vision Care, Inc. (5) · Bayer (5) · National Taiwan University Hospital (5) · Johns Hopkins University (5)
What is being tested here
Drugs under test in Vision Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Sepofarsen | 1 | 3 | 4 |
| Tributyrin | 1 | 0 | 1 |
| Faricimab | 1 | 1 | 1 |
| Fluocinolone Acetonide | 1 | 1 | 1 |
| Phentolamine | 1 | 1 | 1 |
| Valproic Acid | 1 | 0 | 1 |
| Clemastine | 1 | 0 | 1 |
| Cyclopentolate | 1 | 0 | 1 |
| Tropicamide | 1 | 0 | 1 |
| Ranibizumab | 0 | 13 | 22 |
Drug classes tested here Angiogenesis inhibitors 1 open · Corticosteroids 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Aug 2027OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual Acuity · Phase 3 · Opus Genetics, Inc
- Nov 2027Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION) · Phase 3 · Laboratoires Thea
- Nov 2026Evaluating the Integration Model of a Standalone Eye Centre Into Provincial Government Hospital · Seva Canada Society
- Nov 2026Effects of Reformer Pilates and Vestibular Exercise Programs on Balance and Gait in Children With Visual Impairment · Marmara University
- Nov 2026Postural Rehabilitation for Visual Dysfunction in Forward Head Posture · Riphah International University
- Dec 2026Improving Visual Field Deficits With Noninvasive Brain Stimulation · Beth Israel Deaconess Medical Center
- Dec 2026Assessment of Caries Impacts and Experiences in a Visually Impaired Versus Sighted Children Using CARIES-QC/A · Cairo University
- Dec 2026Viewing Strategy Training in Children With (Cerebral) Visual Impairment · Royal Dutch Visio
- Dec 2026Rehabilitation of Visual Function After Brain Injury · University Hospital, Gentofte, Copenhagen
- Jan 2027Non-invasive Induction of Metaplasticity for Amblyopia · Boston Children's Hospital
Who these studies take
Of the 46 Vision Disorders studies recruiting now, 21 (46%) set no upper age limit and 16 (35%) stop at 75 or younger. 18 (39%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 13 (28%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 14 (30%) | 14 (30%) |
| 18 | 32 (70%) | 32 (70%) |
| 30 | 31 (67%) | 31 (67%) |
| 40 | 30 (65%) | 30 (65%) |
| 50 | 31 (67%) | 31 (67%) |
| 65 | 30 (65%) | 30 (65%) |
| 75 | 30 (65%) | 30 (65%) |
| 85 | 27 (59%) | 27 (59%) |
Across all 360 studies, recruiting or not: 30% stop at 75 or younger and 26% at 65; 31% take children; 1% are for women only and <1% for men only; 33% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Vision Disorders studies take
Of 17 phase 3 interventional studies under Vision Disorders, half reached primary completion within 26 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 26 mo21–28 · 17 studies | — | — |
| Interventional, no phase | 24 mo6–51 · 94 studies | — | 31 mo7–51 · 84 studies |
| Observational | 23 mo12–52 · 58 studies | — | 23 mo10–42 · 51 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 360. Browse all 360 → or search them.
- NEURO-COGS: Neurometabolic Mechanisms of Cognitive Training in SchizophreniaNot yet recruitingNCT07788755Not applicable1 country
- Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation RetinopathyRecruitingNCT05844982Phase 31 country
- Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)RecruitingNCT06891443Phase 310 countries
- OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual AcuityRecruitingNCT07140783Phase 31 country
- Evaluation of a Scalable Educational Intervention for Adjustment and Coping to Vision LossEnrolling by invitationNCT07715695Not applicable1 country
- A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)Not yet recruitingNCT06792500Phase 1/21 country
- Visual Impairment and Functional Visual Performance Following Acquired Brain Injury: A Cross-Sectional StudyEnrolling by invitationNCT078587081 country
- SENSE-Brain Health Pro for Older Adults With Sensory LossNot yet recruitingNCT07856888Not applicable1 country
- Pilot Study of Individualized Neurovisual Rehabilitation Following Acquired Brain InjuryNot yet recruitingNCT07849582Not applicable1 country
- Validation of MoCA-B and MoCA-Blind for Screening Cognitive DeclineNot yet recruitingNCT07846839
- Non-invasive Induction of Metaplasticity for AmblyopiaNot yet recruitingNCT07846397Not applicable
- Prospective Evaluation of the 2022 Optic Neuritis Criteria When Optic Neuritis Is SuspectedRecruitingNCT076232521 country
- Virtual Reality Aniseikonia and Metamorphopsia TestingRecruitingNCT07838181Not applicable1 country
- Effectiveness of a Multi-disciplinary Vision Rehabilitation Programme in Improving the Overall Quality of Life of Visually Impaired AdultsRecruitingNCT07827040Not applicable1 country
- How Can the Experience of Hospital Outpatient Departments be Improved?Not yet recruitingNCT078182131 country
- Study to Evaluate the Long-Term Safety of Ultevursen in Participants With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A GeneNot yet recruitingNCT07796646Phase 2
- Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General PracticeRecruitingNCT07015034Not applicable1 country
- Postural Rehabilitation for Visual Dysfunction in Forward Head PostureRecruitingNCT07484555Not applicable1 country
- Mechanisms of Visual Restoration After Occipital StrokeRecruitingNCT071347771 country
- Visual Restoration Using Focused Ultrasound Stimulation and Immersive Virtual Reality After StrokeNot yet recruitingNCT06875206Not applicable1 country
- Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation ResearchRecruitingNCT07623668Phase 31 country
- Body Image, Identity Development, and Social Media Use Among Youth With Visual Impairment: A Single Case Intervention StudyNot yet recruitingNCT07741500Not applicable1 country
- Providing Access to the Visual EnvironmentRecruitingNCT003417441 country
- Valproate for the Treatment of Residual AmblyopiaRecruitingNCT07226141Phase 1/21 country
- VIPPSTAR-G1 Digital Early Intervention for Visual ImpairmentNot yet recruitingNCT07717671Not applicable3 countries
- Promoting Psychophysical Well-being in Children and Adolescents With Visual ImpairmentNot yet recruitingNCT07703150Not applicable1 country
- Survey of Sensory Impairment Indicators Among Adults Aged 65 Years and Older in Xinxing CountyNot yet recruitingNCT076945051 country
- Stem Cell Ophthalmology Treatment Study IIRecruitingNCT03011541Not applicable3 countries
- Assessment of Caries Impacts and Experiences in a Visually Impaired Versus Sighted Children Using CARIES-QC/ANot yet recruitingNCT07665047
- The Proactive Ophthalmic Examination CohortRecruitingNCT058512871 country
- Study Protocol: The Jerte Valley as an Inclusive Outdoor Classroom. Smart and Active Tourism.Not yet recruitingNCT07609459Not applicable
- Implementing Artificial Intelligence to Prevent Vision Loss From DiabetesEnrolling by invitationNCT07559292Not applicable1 country
- Evaluating the Integration Model of a Standalone Eye Centre Into Provincial Government HospitalNot yet recruitingNCT07547527Not applicable
- Touching the World With a Cane: Cognitive and Neural ProcessesRecruitingNCT05199896Not applicable1 country
- Hemianopsia Rehabilitation After Stroke or Brain InjuryRecruitingNCT06241209Not applicable1 country
- Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)RecruitingNCT02521311Phase 21 country
- Visual Frailty in AgeingRecruitingNCT066041041 country
- Virtual Assistance for Daily Living: Neurophysiological and Functional Effects in Low VisionNot yet recruitingNCT07442461Not applicable1 country
- IIH Intervention: A Clinical Trial Comparing 2 Treatments (Shunts and Stents) Evaluation Of Clinical Effectiveness And Cost EffectivenessRecruitingNCT07440277Not applicable1 country
- Multicenter Study of Transcranial Magnetic Stimulation on Vision RestorationNot yet recruitingNCT07425717Not applicable1 country
- Effect of Carotenoids Supplementation on Visual Function in Chinese SubjectsNot yet recruitingNCT06098677Not applicable
- Viewing Strategy Training in Children With (Cerebral) Visual ImpairmentRecruitingNCT05600140Not applicable1 country
- Michigan Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (SIGHT) 2RecruitingNCT06934577Not applicable1 country
- Development of a Multi-sensory Rehabilitation Program for People With Ultra Low VisionRecruitingNCT05028712Not applicable1 country
- Cerebral/ Cortical Visual Impairment: Screening, Identification and Outcome Prediction in NeonatesRecruitingNCT072750211 country
- Natural History Study of Inherited Retinal DiseasesRecruitingNCT070855331 country
- Traditional Exercise RCT in Visually Impaired AdultsEnrolling by invitationNCT07265024Not applicable1 country
- Evaluation of Serum- and OCT Biomarkers in Patients With DME Treated With Anti-VEGF or Dexamethasone ImplantRecruitingNCT06984822Not applicable1 country
- Early Detection and Prevention of Amblyopia and Visual Impairment Through Systematic Pediatric Vision ScreeningNot yet recruitingNCT071125601 country
- Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision LossRecruitingNCT07073521Not applicable1 country