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Critical Illness clinical trials

The registry lists 1,780 studies for Critical Illness across more than 10 countries. 442 are recruiting or about to start. 786 of them are mainly about Critical Illness (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition postintensive care syndrome too: 1,859 studies, 477 open.

ClinicalTrials.gov finds 3,250 studies for Critical Illness. How that becomes 1,777 here

This page counts the studies the registry files under Critical Illness, and those it files under no condition that list Critical Illnessthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 3,250Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −17Filed under a narrower condition, counted on its own pagepostintensive care syndrome 17
  3. −186List Critical Illness as a condition, but the registry did not file them under itMost often written as “Critically Ill Patients” (44), “Critical Illness Myopathy” (17), and “Critically Ill Intensive Care Unit Patients” (12). The registry filed 103 of them under no condition at all, and the others under other conditions only, most often Sepsis (11) and Polyneuropathies (8).
  4. −1,270Match it another way1,179 name it in the title, 54 in a keyword, and 37 by a synonym or other text the search reads.
  5. 1,777The count on this page

Get an email when these change. Save the Critical Illness studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Completed
920
Recruiting
271
Status unknown
230
Not yet recruiting
152
Terminated
89
Active, not recruiting
56

Phase

Phase 2
120
Phase 3
106
Phase 4
94
Phase 1
32
Early Phase 1
7

Where

United States
364
France
130
China
110
Canada
101
United Kingdom
79
Germany
73

Who runs them

Vanderbilt University Medical Center (24) · Australian and New Zealand Intensive Care Research Centre (23) · Assiut University (21) · Duke University (20) · Mayo Clinic (18) · University Medical Center Groningen (17) · Medical University of Vienna (16) · National Taiwan University Hospital (15)

What is being tested here

Drugs under test in Critical Illness studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Dexmedetomidine3415
Sodium Chloride316
Remimazolam314
Midazolam236
Ketamine236
Enoxaparin235
Melatonin203
Nogapendekin alfa inbakicept213
Remimazolam besilate213
Cerebrolysin202

Drug classes tested here Opioids 1 open · Diuretics 1 open · Androgens 1 open · Neuromuscular blockers 1 open · Proton pump inhibitors (PPIs) 3

Coming up

20phase 3 studies under way
173studies finish main data collection within a year8 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 271 Critical Illness studies recruiting now, 208 (77%) set no upper age limit and 31 (11%) stop at 75 or younger. 35 (13%) take children under 18. 2 (1%) are for women only and 1 (<1%) for men only; 18 (7%) take healthy volunteers.

Recruiting studies that take each age, of 271
AgeWomenMen
1029 (11%)28 (10%)
18236 (87%)235 (87%)
30239 (88%)238 (88%)
40241 (89%)240 (89%)
50243 (90%)242 (89%)
65244 (90%)243 (90%)
75241 (89%)240 (89%)
85231 (85%)230 (85%)

Across all 1,780 studies, recruiting or not: 11% stop at 75 or younger and 9% at 65; 15% take children; <1% are for women only and <1% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Critical Illness studies take

Of 36 phase 2 interventional studies under Critical Illness, half reached primary completion within 26 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 226 mo16–39 · 36 studies——
Phase 333 mo20–59 · 33 studies—33 mo20–59 · 32 studies
Phase 430 mo16–41 · 36 studies—30 mo16–41 · 36 studies
Interventional, no phase21 mo12–40 · 403 studies—21 mo12–40 · 399 studies
Observational23 mo12–46 · 442 studies—23 mo12–45 · 439 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting10

Show 5 more

Results posted2

Stopped2

Newly registered27

Show 22 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,780. Browse all 1,780 → or search them.