Cataract clinical trials
The registry lists 1,629 studies for Cataract across more than 10 countries. 235 are recruiting or about to start. 1,342 of them are mainly about Cataract (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Capsule Opacification too: 1,648 studies, 236 open.
ClinicalTrials.gov finds 1,995 studies for Cataract. How that becomes 1,627 here
This page counts the studies the registry files under Cataract, and those it files under no condition that list Cataractthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,995Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −12Filed under a narrower condition, counted on its own pageCapsule Opacification 7
- −108List Cataract as a condition, but the registry did not file them under itMost often written as “Cataract Surgery” (29), “Congenital Cataract” (13), and “Cataract Senile” (12). The registry filed them under other conditions only, most often Dry Eye Syndromes (10) and Anxiety Disorders (9).
- −248Match it another way218 name it in the title, 24 in a keyword, and 6 by a synonym or other text the search reads.
- 1,627The count on this page214 of them list Cataract in their own words; the registry filed them under no condition.
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Who runs them
Alcon Research (115) · Sun Yat-sen University (52) · Bausch & Lomb Incorporated (39) · Beaver-Visitec International, Inc. (36) · Wenzhou Medical University (32) · Vienna Institute for Research in Ocular Surgery (31) · Carl Zeiss Meditec AG (28) · Medical University of Vienna (27)
What is being tested here
Drugs under test in Cataract studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexmedetomidine | 2 | 1 | 6 |
| Levofloxacin | 1 | 1 | 4 |
| Rebamipide | 1 | 0 | 2 |
| Midazolam | 1 | 0 | 2 |
| Hyaluronic Acid | 1 | 0 | 2 |
| Propofol | 1 | 0 | 2 |
| Aflibercept | 1 | 0 | 2 |
| Omega-3 fatty acid | 1 | 1 | 2 |
| Ascorbic Acid | 1 | 1 | 2 |
| Fentanyl | 1 | 0 | 1 |
Drug classes tested here Angiogenesis inhibitors 1 open · Opioids 1 open · Corticosteroids 44 · NSAIDs 15 · Antimuscarinics 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Clinical Study of a Fluid Accommodating Intraocular Lens (IOL) Design · Alcon Research
- Nov 2026Diabetic Nephropathy, Glycemic Control and Pseudophakic Macular Edema After Cataract Surgery · Thammasat University Hospital
- Nov 2026Visual Function of Enhanced Monofocal Intraocular Lenses · Vienna Institute for Research in Ocular Surgery
- Nov 2026The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage · Matthew Rauen
- Nov 2026Dexmedetomidine and Propofol for Sedation in Cataract Surgery. · Saint-Joseph University
- Nov 2026Trial Comparing miLOOP Device Assisted Phacoemulsification vs Standard Surgery for Dense Cataracts: Effects on Endothelial Cell Loss, Energy Use, and Vision Recovery · Universiti Kebangsaan Malaysia Medical Centre
- Nov 2026Intraoperative Aberrometry vs Conventional Intraocular Lens Calculation, a Prospective Study. · Instituto de Oftalmología Fundación Conde de Valenciana
- Dec 2026PureSee/Odyssey Mix-and-Match IOL · Gainesville Eye Associates
- Dec 2026Vision Center Determinants of Cataract Follow-Up in Rural India · Seva Canada Society
- Dec 2026Rebamipide Versus Diquafosol for Perioperative Dry Eye in Cataract Surgery · Samsung Medical Center
Who these studies take
Of the 141 Cataract studies recruiting now, 88 (62%) set no upper age limit and 8 (6%) stop at 75 or younger. 10 (7%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 16 (11%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 10 (7%) | 10 (7%) |
| 18 | 67 (48%) | 67 (48%) |
| 30 | 95 (67%) | 95 (67%) |
| 40 | 112 (79%) | 112 (79%) |
| 50 | 132 (94%) | 132 (94%) |
| 65 | 139 (99%) | 139 (99%) |
| 75 | 138 (98%) | 138 (98%) |
| 85 | 121 (86%) | 121 (86%) |
Across all 1,629 studies, recruiting or not: 10% stop at 75 or younger and 6% at 65; 12% take children; <1% are for women only and <1% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Cataract studies take
Of 46 phase 4 interventional studies under Cataract, half reached primary completion within 20 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 13 mo9–38 · 31 studies | 11 mo9–15 · 23 studies | — |
| Phase 4 | 20 mo11–34 · 46 studies | — | 22 mo11–39 · 39 studies |
| Interventional, no phase | 17 mo9–28 · 490 studies | 16 mo10–28 · 190 studies | 18 mo7–30 · 300 studies |
| Observational | 16 mo9–30 · 234 studies | 13 mo8–35 · 67 studies | 19 mo9–30 · 167 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting2
- Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital PopulationOct 27, 2026NCT05157113
- Clinical Evaluation of a Novel Trifocal IOLOct 21, 2026NCT07587138
Results posted1
- Evaluation of Aqueous Humor DEL-1 and IL-17 Levels in Diabetic Cataract PatientsOct 19, 2026NCT06995131
Stopped1
- Feasibility Study of an Accommodating IOL DesignTerminatedOct 29, 2026NCT07147192
Newly registered10
- A Multi Center Evaluation of TearCare on Surgical Measurements Before Cataract SurgeryNov 10, 2026NCT07928986
- Rotational Stability of the Acunex Vario ToricNov 9, 2026NCT07925840
- Safety and Clinical Performance of the LENTIS® MAX LS-313 MF80 Compared With the Monofocal L-313 in Cataract Patients With Late Age-Related Macular Degeneration: A Multicenter Comparative Clinical Investigation.Nov 4, 2026NCT07915076
- Anterior Segment Anatomy Assessed by Swept-Source OCT in Ocular Surgery PatientsOct 29, 2026NCT07903454
- A Case-Control Study Revealing Intraocular Microenvironment Characteristics in Patients With Ocular Diseases Based on Multi-Omics AnalysisOct 27, 2026NCT07897513
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- Trial Comparing miLOOP Device Assisted Phacoemulsification vs Standard Surgery for Dense Cataracts: Effects on Endothelial Cell Loss, Energy Use, and Vision RecoveryOct 27, 2026NCT07898007
- PureSee/Odyssey Mix-and-Match IOLOct 27, 2026NCT07898917
- Manipulating Temporal Expectations to Accelerate Recovery After Cataract SurgeryOct 27, 2026NCT07899112
- Postoperative Outcome Verification of Discrepant Toric IOL Calculator Recommendations After Cataract SurgeryOct 19, 2026NCT07880249
- Imaging and Spectral Analysis of the Crystalline Lens Using the "HYPERLAF" Slit LampOct 15, 2026NCT07875205
Studies
Recruiting first, then most recently updated. Showing 50 of 1,629. Browse all 1,629 → or search them.
- A Multi Center Evaluation of TearCare on Surgical Measurements Before Cataract SurgeryRecruitingNCT079289861 country
- Rotational Stability of the Acunex Vario ToricRecruitingNCT07925840Not applicable1 country
- Implementing AI-based Glaucoma Screening Within Federally Qualified Health CentersRecruitingNCT06629649Not applicable1 country
- Effects of Oxygen Cage Support During Cataract SurgeryNot yet recruitingNCT07632326Not applicable
- Safety and Clinical Performance of the LENTIS® MAX LS-313 MF80 Compared With the Monofocal L-313 in Cataract Patients With Late Age-Related Macular Degeneration: A Multicenter Comparative Clinical Investigation.Not yet recruitingNCT07915076Not applicable
- Clareon TruPlus StudyRecruitingNCT07502456Not applicable1 country
- Capella Scientia Development StudyRecruitingNCT069874744 countries
- Anterior Segment Anatomy Assessed by Swept-Source OCT in Ocular Surgery PatientsRecruitingNCT079034541 country
- Surgical Procedure Efficiency Evaluation stuDyRecruitingNCT072280911 country
- Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital PopulationRecruitingNCT05157113Phase 41 country
- Trial Comparing miLOOP Device Assisted Phacoemulsification vs Standard Surgery for Dense Cataracts: Effects on Endothelial Cell Loss, Energy Use, and Vision RecoveryRecruitingNCT07898007Not applicable1 country
- Treatment of Retinal Detachment in People Who Have Not Had Cataract Surgery With Vitrectomy vs Vitrectomy and Cataract RemovalRecruitingNCT06997874Phase 31 country
- PureSee/Odyssey Mix-and-Match IOLNot yet recruitingNCT078989171 country
- A Case-Control Study Revealing Intraocular Microenvironment Characteristics in Patients With Ocular Diseases Based on Multi-Omics AnalysisNot yet recruitingNCT07897513
- Clinical Evaluation of a Novel Trifocal IOLRecruitingNCT07587138Not applicable3 countries
- Postoperative Outcome Verification of Discrepant Toric IOL Calculator Recommendations After Cataract SurgeryNot yet recruitingNCT07880249
- Intraoperative OCT Guidance of Intraocular Surgery IIRecruitingNCT037132681 country
- Study on Eye-Brain Cross-Organ Mapping and Systemic Disease Association Based on Multimodal Big DataNot yet recruitingNCT07541651
- Imaging and Spectral Analysis of the Crystalline Lens Using the "HYPERLAF" Slit LampNot yet recruitingNCT07875205Not applicable1 country
- Clinical Evaluation of Visual Performance, Spectacle Independence, and Patient Satisfaction With TECNIS PureSee Mini-Monovision and TECNIS PureSee-TECNIS Odyssey Mix-MatchNot yet recruitingNCT07860567Phase 41 country
- "Comparative Study of High-frequency Pulsed Vacuum Technology Versus Phacoemulsification for Cataract SurgeryRecruitingNCT07074431Not applicable1 country
- Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract SurgeryRecruitingNCT07715591Not applicable1 country
- Efficacy and Safety of Tran Cannula in Combined Pseudoexfoliative Glaucoma and Cataract Surgery Compared With Augmented Ocular IrrigationRecruitingNCT06979752Not applicable1 country
- A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract SubjectsRecruitingNCT06922084Phase 41 country
- Intracameral Levofloxacin Versus Moxifloxacin After Cataract SurgeryNot yet recruitingNCT07850414Not applicable
- Evaluation of Safety and Effectiveness of an IOL With a Virtual Aperture OpticRecruitingNCT05955846Not applicable3 countries
- Pilot Study: Feasibility and Usability of a Head-Mounted Spatial Computing Device for Intraoperative Visualization During Intraocular SurgeryRecruitingNCT078253371 country
- Combined Phacoemulsification-Goniotomy in Primary Open-Angle and Primary Angle-Closure GlaucomaNot yet recruitingNCT07821827Not applicable
- Evaluation of Vitreous Modifications After Cataract SurgeryRecruitingNCT078168871 country
- Post-Market Clinical Follow-Up Study on the Rotational Stability of an Intraocular Lens After Cataract SurgeryNot yet recruitingNCT07099079
- The Effect of Topical Rho-kinase Inhibitors on Corneas of Patients With Fuchs Endothelial Corneal DystrophyEnrolling by invitationNCT069695861 country
- Katarak Surgery and CareNot yet recruitingNCT07807761
- Postoperative Outcomes of a Toric AddOn Intraocular Lens After Keratoplasty and Cataract SurgeryRecruitingNCT074520421 country
- Clareon TruPlus vs Tecnis Eyhance IOLs in Cataract PatientsRecruitingNCT076580401 country
- Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General PracticeRecruitingNCT07015034Not applicable1 country
- A Prospective, Single-Arm Clinical Evaluation of Visual, Refractive, and Patient-Reported Outcomes Following Bilateral Implantation of the TECNIS PureSee™ Extended Depth of Focus Intraocular LensNot yet recruitingNCT07790887Phase 41 country
- Post-operative Cognitive Decline After Ambulatory Cataract Surgery in the Elderly PopulationNot yet recruitingNCT077141741 country
- Partial Range Of Field IOLs in DMEK-Enabled ProceduresNot yet recruitingNCT07441616Not applicable1 country
- Guangke Lenses in Congenital CataractRecruitingNCT07778797Not applicable1 country
- Lacrifill for Ocular Surface Optimization in Cataract SurgeryRecruitingNCT076480951 country
- Corneal Biomechanics and Surgically Induced Astigmatism in Pseudoexfoliation SyndromeRecruitingNCT077222471 country
- Night Driving After Trifocal Versus Monofocal IOL ImplantationNot yet recruitingNCT077551891 country
- Postoperative CCT in FECD vs. Non-FECDNot yet recruitingNCT07731945
- Clinical Evaluation of the Adaptilens Accommodating IOLNot yet recruitingNCT07607860Not applicable
- Visual Adaptation and Quality of Life After Different IOL Implantation StrategiesRecruitingNCT077405901 country
- Safety and Efficacy of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract SurgeryRecruitingNCT07036510Phase 1/21 country
- AI-Driven IOL Prediction Using SS-OCT BiometryNot yet recruitingNCT077331543 countries
- JASPER™ Robotic Surgical System (Formerly Known as the ORYOM™ Robotic Surgical System) in Cataract SurgeryRecruitingNCT07468409Not applicable1 country
- Post-refractive IOL Outcomes With Clareon TruPlusRecruitingNCT076102261 country
- Influence of Cataract Surgery on Corneal Biomechanical Properties in Patients With Pseudoexfoliation SyndromeNot yet recruitingNCT077191011 country