Strabismus clinical trials
The registry lists 142 studies for Strabismus across more than 10 countries. 31 are recruiting or about to start. 81 of them are mainly about Strabismus (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-20. Counting its 2 narrower conditions too, such as Esotropia: 210 studies, 46 open.
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Who runs them
National Eye Institute (NEI) (9) · Assiut University (6) · Rebiscan, Inc. (5) · Alaska Blind Child Discovery (5) · Cairo University (5) · Minia University (5) · Shahid Beheshti University of Medical Sciences (4) · Tanta University (4)
What is being tested here
Drugs under test in Strabismus studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Propofol | 1 | 0 | 4 |
| Ketamine | 1 | 0 | 2 |
| Botulinum toxin type A | 1 | 1 | 1 |
| Dexmedetomidine | 0 | 0 | 3 |
| Dexamethasone | 0 | 0 | 2 |
| Midazolam | 0 | 0 | 2 |
| Bupivacaine | 0 | 1 | 2 |
| Sugammadex | 0 | 0 | 1 |
| Pyridostigmine | 0 | 0 | 1 |
| Rocuronium | 0 | 0 | 1 |
Drug classes tested here Local anesthetics 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7
- Nov 2026Ocular Characteristics in Patients With Craniosynostosis · Centre Hospitalier Universitaire, Amiens
- Dec 2026Intraoperative OCT Guidance of Intraocular Surgery II · Duke University
- Mar 2027Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy · The Cleveland Clinic
- May 2027Risk Factors And Surgical Outcomes Of Strabismus Reoperation · Assiut University
- May 20273D Movie Viewing vs Occlusion for Treating Amblyopia in Children · Universitat Politècnica de Catalunya
- Jun 2027Clinical Validation of AI-Based Quantitative Eye Movement Analysis From Smartphone 9-Gaze Videos (Glandy EOM) · THYROSCOPE INC.
- Nov 2027Effect of Ketamine-Propofol Total Intravenous Anesthesia Versus Sevoflurane-Based Anesthesia on Postoperative Vomiting in Children Undergoing Strabismus Surgery · Assiut University
Who these studies take
Of the 13 Strabismus studies recruiting now, 6 (46%) set no upper age limit and 5 (38%) stop at 75 or younger. 13 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 6 (46%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 11 (85%) | 11 (85%) |
| 18 | 11 (85%) | 11 (85%) |
| 30 | 10 (77%) | 10 (77%) |
| 40 | 10 (77%) | 10 (77%) |
| 50 | 9 (69%) | 9 (69%) |
| 65 | 9 (69%) | 9 (69%) |
| 75 | 8 (62%) | 8 (62%) |
| 85 | 8 (62%) | 8 (62%) |
Across all 142 studies, recruiting or not: 62% stop at 75 or younger and 61% at 65; 85% take children; 0% are for women only and 0% for men only; 29% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Strabismus studies take
Of 35 interventional studies with no phase under Strabismus, half reached primary completion within 17 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 17 mo8–46 · 35 studies | — | 17 mo8–46 · 35 studies |
| Observational | 24 mo7–50 · 26 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered2
- Comparative Study Of Combined Recession-Resection And Fenestration of Superior Rectus Muscle for Treatment of Dissociated Vertical DeviationOct 20, 2026NCT07883681
- Effect of Ketamine-Propofol Total Intravenous Anesthesia Versus Sevoflurane-Based Anesthesia on Postoperative Vomiting in Children Undergoing Strabismus SurgeryOct 13, 2026NCT07871292
Studies
Recruiting first, then most recently updated. Showing 50 of 142. Browse all 142 → or search them.
- Comparative Study Of Combined Recession-Resection And Fenestration of Superior Rectus Muscle for Treatment of Dissociated Vertical DeviationNot yet recruitingNCT07883681Not applicable
- Intraoperative OCT Guidance of Intraocular Surgery IIRecruitingNCT037132681 country
- Effect of Ketamine-Propofol Total Intravenous Anesthesia Versus Sevoflurane-Based Anesthesia on Postoperative Vomiting in Children Undergoing Strabismus SurgeryNot yet recruitingNCT07871292Phase 4
- Attention-based Binocular Training for Impaired Stereopsis (BRAVE)Not yet recruitingNCT07803458Not applicable1 country
- Japanese Strabismus Outcomes Assessment and Research Group StudyNot yet recruitingNCT077634571 country
- Clinical Validation of AI-Based Quantitative Eye Movement Analysis From Smartphone 9-Gaze Videos (Glandy EOM)Not yet recruitingNCT076238371 country
- Visual Therapy for Intermittent StrabismusNot yet recruitingNCT07563959Not applicable
- 3D Movie Viewing vs Occlusion for Treating Amblyopia in ChildrenNot yet recruitingNCT07563946Not applicable
- Evaluation of a County-Based Eye Health Service Model in Rural Chinese ChildrenRecruitingNCT075477481 country
- A Randomized Trial of Botulinum Toxin A vs Strabismus Surgery for Esotropia >10 to ≤30PDNot yet recruitingNCT07470164Phase 3
- Comparative Study Between Using Combined Propofol Sedation With subTenon's Infusion as Local Anaesthsia to the Eye Versus General Anesthesia for Strabismus Surgery in AdultsNot yet recruitingNCT07504354Not applicable
- Risk Factors And Surgical Outcomes Of Strabismus ReoperationNot yet recruitingNCT07446621Not applicable1 country
- Visual Function Abnormalities in Strabismus and Amblyopia and Response to TherapyRecruitingNCT043102411 country
- Ocular Characteristics in Patients With CraniosynostosisRecruitingNCT069287271 country
- Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated AnomaliesRecruitingNCT030594201 country
- VISION-3D: Visual Skills Improvement With On-screen 3D Movies.Not yet recruitingNCT07301645Not applicable
- Establishing New Treatment Approaches for Amblyopia: Perceptual Learning and Video GamesRecruitingNCT05522972Not applicable1 country
- Genetic Studies of Strabismus, Nystagmus, and Associated DisordersRecruitingNCT047705191 country
- Botulinum Toxin for Strabismus TreatmentNot yet recruitingNCT07180394Not applicable1 country
- Medial Rectus Tendon Width and Surgical Dose Response in Commitant Esotropic PatientsNot yet recruitingNCT07152964
- Refractive and Topographic Changes After Strabismus SurgeryNot yet recruitingNCT06929130
- Highly Aspherical Lenslet (HAL) and Binocular Vision (BV) Disorders [HALT X(T) Study]Not yet recruitingNCT06863675Phase 31 country
- Balance in the Strabismic Patient Undergoing Strabismus SurgeryRecruitingNCT067332201 country
- Exercise Training on a Mirror for Intermittent Exotropia Control Post Strabismus SurgeryNot yet recruitingNCT06762067Not applicable
- Low Flow Anesthesia in Children Undergoing Strabismus SurgeryNot yet recruitingNCT06560268Phase 4
- The Alaska Oculocardiac Reflex StudyRecruitingNCT043539601 country
- Lees Screen in Concomitant StrabismusRecruitingNCT04213053Not applicable1 country
- Comparison Between Peribulbar And Sub-tenon Blocks on Oculocardiac Reflex (OCR) During Pediatric Strabismus SurgeryRecruitingNCT06293586Not applicable1 country
- New Pediatric Patching Method to Improve ComplianceRecruitingNCT02236351Not applicable1 country
- Tilted Gaze Target Test in the Examination of Children With Superior Oblique Muscle PalsyNot yet recruitingNCT05882552Not applicable
- IOBT Versus IO-Rec for Hypertropia With IOOA (IIHIOOA)RecruitingNCT05415553Not applicable1 country
- Morning Versus Evening Patching in Childhood AmblyopiaCompletedNCT07294599Not applicable1 country
- Pain After Strabismus SurgerySuspendedNCT06689943Phase 21 country
- The Occurrence of Emergence Agitation in Pediatric Strabismus SurgeryCompletedNCT06035757Phase 41 country
- Bilateral Lateral Rectus Recession Versus Unilateral Recess-Resect for Intermittent ExotropiaCompletedNCT01032603Not applicable1 country
- Accommodative Changes After Medial Rectus Resection Versus Plication in Primary ExotropiaCompletedNCT07637253Not applicable1 country
- Deep Neuromuscular Blockade in Strabismus SurgeryCompletedNCT05882643Not applicable1 country
- Eye Alignment and Eye Control Changes Through Follow up Period After Application of Eye Exercises Post Strabismus SurgeryCompletedNCT065432121 country
- Parents' Experiences of Administration Eye DropsCompletedNCT071892731 country
- Mobile Medical Application for Cost-effective Strabismus ScreeningCompletedNCT034509801 country
- Comparing General Anesthesia With Single Injection Peribulbar Block With 3 Different DrugsCompletedNCT05728151Not applicable1 country
- Physical Activity on Eye Hand Coordination Post Strabismus SurgeryCompletedNCT06759792Not applicable1 country
- Peribulbar Rocuronium in Adult Strabismus SurgeryCompletedNCT04821817Not applicable1 country
- Preoperative Ondansetron Lozenge for Prevention of Postoperative Nausea and Vomiting in Pediatrics Undergoing Squint SurgeriesCompletedNCT06423820Not applicable1 country
- Performance of 2WIN Photoscreener With Corneal Reflex Compared to School Bus Retinoscopy by AAPOS GuidelinesCompletedNCT036680671 country
- Virtual Reality Test of StrabismusTerminatedNCT041567631 country
- Amblyopia and Strabismus Detection Using Retinal Birefringence ImagingWithdrawnNCT039197081 country
- Intravenous Versus Peribulbar Dexmedetomidine for Strabismus Surgery in AdultsCompletedNCT05215158Not applicable1 country
- Single Minimal Conjunctival Incision for StrabismusCompletedNCT059878781 country
- Inferior Oblique Muscle Anteriorization Versus Anteriorization and Resection in DVD With IOOACompletedNCT05980962Not applicable1 country