Esotropia clinical trials
The registry lists 36 studies for Esotropia across more than 10 countries. 11 are recruiting or about to start. 23 of them are mainly about Esotropia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.
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Who runs them
Eye & ENT Hospital of Fudan University (3) · Jaeb Center for Health Research (3) · National Eye Institute (NEI) (3) · Universitat Politècnica de Catalunya (2) · Rigshospitalet, Denmark (1) · National Taiwan University Hospital (1) · Foundation University Islamabad (1) · University of Campinas, Brazil (1)
What is being tested here
Drugs under test in Esotropia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Botulinum toxin type A | 1 | 1 | 2 |
| Cyclopentolate | 1 | 0 | 1 |
| Tropicamide | 1 | 0 | 1 |
| Bupivacaine | 0 | 1 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- May 2027Risk Factors And Surgical Outcomes Of Strabismus Reoperation · Assiut University
Who these studies take
Of the 5 Esotropia studies recruiting now, 2 (40%) set no upper age limit and 3 (60%) stop at 75 or younger. 4 (80%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (40%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (80%) | 4 (80%) |
| 18 | 4 (80%) | 4 (80%) |
| 30 | 4 (80%) | 4 (80%) |
| 40 | 4 (80%) | 4 (80%) |
| 50 | 3 (60%) | 3 (60%) |
| 65 | 3 (60%) | 3 (60%) |
| 75 | 2 (40%) | 2 (40%) |
| 85 | 2 (40%) | 2 (40%) |
Across all 36 studies, recruiting or not: 67% stop at 75 or younger and 67% at 65; 83% take children; 0% are for women only and 0% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 36 of 36. search them.
- Vision Therapy Versus Prism Treatment in Small-angle Acute Acquired Concomitant EsotropiaRecruitingNCT06622044Not applicable1 country
- Visual Therapy for Intermittent StrabismusNot yet recruitingNCT07563959Not applicable
- A Randomized Trial of Botulinum Toxin A vs Strabismus Surgery for Esotropia >10 to ≤30PDNot yet recruitingNCT07470164Phase 3
- Risk Factors And Surgical Outcomes Of Strabismus ReoperationNot yet recruitingNCT07446621Not applicable1 country
- Genetic Studies of Strabismus, Nystagmus, and Associated DisordersRecruitingNCT047705191 country
- Botulinum Toxin for Strabismus TreatmentNot yet recruitingNCT07180394Not applicable1 country
- Prism Adaptation in Symptomatic Esophoria - Effect of Shorter Time Intervals and Surgical Outcomes Based on Prism AdaptationRecruitingNCT06729710Not applicable1 country
- Accommodation-Related Visual Training Combined with Transcranial Electrical Stimulation Versus Visual Training Alone for the Treatment of Accommodation DysfunctionNot yet recruitingNCT06714890Not applicable1 country
- Botulinum Toxin Injection Versus Prism Treatment in Small-angle Acute Acquired Concomitant EsotropiaNot yet recruitingNCT06714877Not applicable1 country
- Medial Rectus Fenestration vs Recession for PAETRecruitingNCT06298929Not applicable1 country
- Cycloplegic Refraction in Pediatric Patients With EsotropiaRecruitingNCT06077682Phase 42 countries
- An Observational Cohort Study to Explore the Clinical Outcome of Congenital Strabismmus Based on Etiology and Timing of SurgeryActive, not recruitingNCT066143351 country
- Bifocal Spectacles vs. Single Vision Spectacles for Esotropia Greater at NearWithdrawnNCT05527015Phase 3
- Efficacy of Botulinum Toxin Type A for Acute Acquired Comitant Esotropia: An Age-Stratified Two-Year Follow-Up StudyCompletedNCT06966999Not applicable1 country
- Study of Clinical Types and Treatment Outcomes of Pediatric Esotropia in Sohag University HospitalCompletedNCT06221098Not applicable1 country
- Botox Instead of Strabismus Surgery (BISS)CompletedNCT03459092Phase 32 countries
- Performance and Safety Evaluation of the S360 Medical Device Software.Status unknownNCT05522595Not applicable1 country
- Validation of a Smartphone-based Intelligent Diagnosis and Measurement for StrabismusStatus unknownNCT056155191 country
- Characteristics of the Vergence Responses of Binocularly Normal Subjects After a Vision Therapy ProtocolStatus unknownNCT05208658Not applicable1 country
- Changes in Refractive Error in Patients With Both Partially Refractive Esotropia and AmblyopiaCompletedNCT044296591 country
- Bupivacaine Injection of Eye Muscles to Treat StrabismusStatus unknownNCT01616108Phase 2/31 country
- Augmented Medial Rectus Muscle Recession Versus Posterior Scleral Fixation in Partially Accommodative EsotropiaCompletedNCT02413463Not applicable1 country
- Strabismus Surgery and Driving AbilityCompletedNCT025705551 country
- Early Versus Delayed Surgery for Infantile EsotropiaCompletedNCT011665031 country
- Conservative Treatment of Esotropia in Children up to 3 Years OldStatus unknownNCT02404324Not applicable
- Binocular Treatment of Amblyopia Before and After Strabismus SurgeryCompletedNCT01791946Not applicable1 country
- Bifocal Soft Contact Lenses and Their Effect on Myopia Progression in Children and Adolescents.CompletedNCT00214487Not applicable
- Comparison of Two Treatments for Strabismus Correction: Botulinum Toxin A Associated to Surgery and Surgery AloneCompletedNCT01460355Phase 41 country
- An Observational Study of Infantile, Acquired Non-accommodative, and Acquired Partially-accommodative EsotropiaCompletedNCT003109601 country
- Surgery for Esotropia Under Topical AnesthesiaStatus unknownNCT00993174Not applicable1 country
- Under-correction in Refractive Accommodative EsotropiaCompletedNCT01179711Not applicable1 country
- Congenital Esotropia Observational Study (CEOS)CompletedNCT00000163
- The Prism Adaptation Study (PAS)CompletedNCT00000121Phase 3
- Long-Term Outcomes in the Treatment of Infantile and Acquired Esotropia With Botulinum ToxinCompletedNCT007463041 country
- Bilateral Recession or Unilateral Recession-Resection as Surgery for Infantile EsotropiaCompletedNCT003045772 countries
- A Trial of Bifocals in Myopic Children With EsophoriaStatus unknownNCT00000128Phase 3