An interventional study of moderate to deep neuromuscular blockade and shallow to minimal neuromuscular blockade in Strabismus, sponsored by Seoul National University Hospital. Completed at 1 site in South Korea. Open to participants aged 3 Years to 18 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-23.
Sponsored by Seoul National University Hospital · Not applicable, Interventional, and Prevention
The purpose of this study is to determine if inducing a moderate or greater neuromuscular block (TOF count 0-3) when performing a neuromuscular block in pediatric patients aged 3 to 18 years undergoing strabismus surgery under general anesthesia can reduce the incidence of the oculocardiac reflex.
142 studies on the registry are indexed under Strabismus; 31 are open to participants now.
This study's enrollment of 201 is above the median of 60 across 82 interventional studies indexed under Strabismus.
Browse Strabismus studies →Seoul National University Hospital is the lead sponsor of 1,900 studies on the registry; 274 are open to participants now.
Of its 12 completed or terminated interventional studies of FDA-regulated products, 2 (17%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
A recording of the heart’s electrical activity, taken with stickers on the chest, arms and legs. It takes a few minutes and does not hurt.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
ECG (electrocardiogram)
A recording of the heart’s electrical activity, taken with stickers on the chest, arms and legs. It takes a few minutes and does not hurt.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
* Maintaining moderate to deep neuromuscular blockade during an intraoperative period (Train-of-four 0-3, post-tetanic count \> 1) * Rocuronium (intravenous, 1.0 mg/kg)
Other: moderate to deep neuromuscular blockade
* Maintaining shallow to minimal neuromuscular blockade during an intraoperative period (Train-of-four 4, post-tetanic count \< 0.9) * Rocuronium (intravenous, 0.3 mg/kg)
Other: shallow to minimal neuromuscular blockade
* Maintaining moderate to deep neuromuscular blockade during an intraoperative period (Train-of-four 0-3 count, post-tetanic count \> 1) * Rocuronium (intravenous, 1.0 mg/kg at induction period)
* Maintaining shallow to minimal neuromuscular blockade during an intraoperative period (Train-of-four 4, post-tetanic count \< 0.9) * Rocuronium (intravenous, 0.3 mg/kg at induction period)
The incidence of grade 2 or greater oculocardiac reflex (during strabismus surgery)
\> 20% reduction in heart rate during strabismus surgery
Time frame: Day 1, During general anesthesia for strabismus surgery (within 2 hours).
The incidence of grade 1 oculocardiac reflex (during strabismus surgery)
\< 20% reduction in heart rate during general anesthesia for strabismus surgery (within 2 hours).
Time frame: Day 1, During general anesthesia for strabismus surgery (within 2 hours).
The incidence of grade 3 or greater oculocardiac reflex (during strabismus surgery)
\> 30% decrease in heart rate (moderate oculocardiac reflex) during strabismus surgery
Time frame: During general anesthesia for strabismus surgery (usually within 2 hour)
The incidence of hypotension
The incidence of hypotension, defined as a drop to 20% or more of baseline mean blood pressure
Time frame: During general anesthesia for strabismus surgery (within 2 hour)
Postoperative nausea/vomiting
Presence of postoperative nausea/vomiting as assessed in the recovery room
Time frame: From extubation to post-anesthesia care unit stay (within 1 hour)
Results from a refraction test before strabismus surgery
Results from a refraction test before strabismus surgery measured at outpatient clinic
Time frame: Before strabismus surgery (within 12 month)
Results from a refraction test at strabismus surgery
Results from a refraction test during strabismus surgery
Time frame: During general anesthesia for strabismus surgery (within 2 hour)
Ran from Oct 2024 to primary completion in Nov 2025, 13 months.
Of 35 non-industry interventional studies with no phase under Strabismus, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 46. This study's 13 months is below that.
Counting every sponsor, half of 35 studies reached it within 17 months; a quarter within 8 and three quarters within 46.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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Seoul National University Hospital →