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Not yet recruitingNCT07152964Updated Sep 3, 2025

Medial Rectus Tendon Width and Surgical Dose Response in Commitant Esotropic Patients

An observational study in Strabismus, sponsored by Assiut University. Not yet recruiting. Per ClinicalTrials.gov, last updated 2025-09-03.

Sponsored by Assiut University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
28
Sex
All
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Study summary

This study aims to investigate the clinical correlation between medial rectus tendon width and surgical dose response in esotropic patients undergoing medical rectus recession

Read the detailed description

Esotropia is a type of strabismus where one or both eyes turn inward(1).Medial rectus tendon width is horizontal thickness of the tendon of the medial rectus muscle, one of the extraocular muscles.Medial rectus recession is a standard surgical treatment for esotropia involving weakening the medial rectus muscle by repositioning it posteriorly(2).Surgical Dose Response describes how much eye alignment in prism diopters is achieved per millimeter of muscle recession.

Studies on medial rectus resection revealed that higher medial rectus tendon width (MRTW) was associated with a larger surgical dose-response(3).Other studies revealed that the effect of lateral rectus recession in patients with intermittent exotropia was larger in cases with narrower lateral rectus tendon width (4,5).

The potential impact of medial rectus tendon width on the effectiveness of medial rectus recession had not been studied.

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Conditions studied

  • Strabismus

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03

In context

Strabismus

142 studies on the registry are indexed under Strabismus; 31 are open to participants now.

This study's planned enrollment of 28 is below the median of 96 across 54 observational studies indexed under Strabismus.

Browse Strabismus studies →

Lead sponsor

Assiut University is the lead sponsor of 5,078 studies on the registry; 2,178 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All patients with comitant esotropia scheduled for unilateral or bilateral medial rectus recession

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

- All patients with comitant esotropia scheduled for unilateral or bilateral medial rectus recession

Exclusion criteria

Exclusion Criteria:

  • previous extraocular muscle surgery Incomitant esotropia
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
28 participants (estimated)
Patient registry
No

Interventions

  • DeviceCaliper

    Measure medial rectus tendon width with caliper intraoperative

06

What researchers measure

Primary outcomes

  1. Clinical correlation between medial rectus tendon width and surgical dose response in comitant esotropic patients undergoing medial rectus recession

    Can medial rectus tendon width affect surgical dose response in commitant esotropic patients undergoing medial rectus recession

    Time frame: Baseline

  2. Variation in medial rectus tendon width in different age groups

    Time frame: Baseline

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Study locations

No study locations are listed for this record.

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References and documents

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Sep 2025; primary completion for Sep 2026, 12 months later.

Of 26 observational studies under Strabismus, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 50. This study's planned 12 months is below that.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 26, 2025
First posted
Sep 3, 2025
StartEst.
Sep 2025
Primary completionEst.
Sep 2026
CompletionEst.
Oct 2026
Last update
Sep 3, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 3, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07152964
Lead sponsor
Assiut University
Responsible party
Reham Yahya Abdel Mohsen AbdelHafez (Resident doctor, Assiut University) — Principal investigator
First posted
Sep 3, 2025
Start date
Sep 2025 (estimated)
Primary completion
Sep 2026 (estimated)
Completion
Oct 2026 (estimated)
Last update
Sep 3, 2025

Study contacts

Reham Yahya AbdelMohsen, Resident doctor
Contact
rehamyahya123456@gmail.com
+201140167502
Ali Natag Riad, Professor
study director · Assiut University
Mohammed Anwr Sayed, Assistant professor
study director · Assiut University
Sara Hussein AlAttar, Assistant professor
study director · Assiut University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.

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Discussion

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