DrugSupplement
Ascorbic Acid clinical trials
Also written Vitamin C, Ascor and Cevalin.
Includes 4 studies of Isoascorbic acid.
- studies test it
- 408
- open now
- 60
- in phase 3
- 50
- first study started
- 1993
Keep track of what changes. Save the Ascorbic Acid studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
404 studies that test it; most in 2018 (36)
| Year | Studies |
|---|---|
| 1993 | 1 |
| 1995 | 1 |
| 1997 | 1 |
| 1998 | 1 |
| 2000 | 2 |
| 2002 | 3 |
| 2003 | 3 |
| 2004 | 5 |
| 2005 | 8 |
| 2006 | 5 |
| 2007 | 10 |
| 2008 | 15 |
| 2009 | 10 |
| 2010 | 14 |
| 2011 | 17 |
| 2012 | 9 |
| 2013 | 12 |
| 2014 | 13 |
| 2015 | 13 |
| 2016 | 18 |
| 2017 | 24 |
| 2018 | 36 |
| 2019 | 35 |
| 2020 | 32 |
| 2021 | 16 |
| 2022 | 14 |
| 2023 | 25 |
| 2024 | 23 |
| 2025 | 22 |
| 2026 | 16 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 16
- Phase 1
- 60
- Phase 2
- 128
- Phase 3
- 50
- Phase 4
- 49
- No phase
- 144
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 23 · Other 385
Cairo University (12) · Ain Shams University (10) · Virginia Commonwealth University (8) · University of Kansas Medical Center (6) · Augusta University (6) · Seoul National University Hospital (5) · Joseph J. Cullen, MD, FACS (4) · University of Wisconsin, Madison (4)
Often tested with
Tested in the same studies.
Vitamin E (31) · Thiamine (14) · Arsenic Trioxide (13) · Polyethylene Glycols (12) · Zinc (10) · Thioctic Acid (9) · Glutathione (7) · Gemcitabine (7)
Studies
Open first, then newest update. How each study uses Ascorbic Acid is read from its arms, and is right about nine times in ten.
Testing it · 408
- COMPARISON OF TOPICAL VITAMIN C VS NIACINAMIDE IN TREATMENT OF MELASMANot yet recruitingNot applicablePak Emirates Military HospitalNCT07890571Written as Ascorbic acid
- Rutin and Ascorbic Acid for Prevention of Vancomycin-Induced Nephrotoxicity in Adult Patients" - a Clinical Trial Protocol Evaluating Whether Combined Rutin/Vitamin C Supplementation Reduces Kidney Toxicity From Vancomycin, Compared to Vitamin C Alone and Control.Enrolling by invitationNot applicableAin Shams UniversityNCT07873372Written as Rutin + Ascorbic Acid (RUTA C60®)
- Vitamin C With Steroids for Gastrointestinal GVHDNot yet recruitingEarly Phase 1Baylor College of MedicineNCT07197749Written as Vitamin C (Ascorbic Acid)
- Effect of Vitamin C Administration on Intraoperative Bleeding in Patients Undergoing SinusoscopyNot yet recruitingPhase 2Assiut UniversityNCT07866274Written as Ascorbic acid
- A Study to Investigate Bowel Cleansing With PLENVU® Compared to Sodium Picosulfate in Participants Aged 1 to < 18 Years of Age in Preparation for ColonoscopyRecruitingPhase 3NorgineNCT07218523Written as PLENVU®
- Injectable Platelet-Rich Fibrin and Microneedling With or Without Vitamin C for Gingival Phenotype Augmentation.Not yet recruitingNot applicableUniversity of Science and Technology, YemenNCT07848035Written as Vitamin C
- Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic LeukemiaRecruitingPhase 2Mayo ClinicNCT03418038Written as Ascorbic Acid
- : Vascular Function in Health and DiseaseRecruitingPhase 1D. Walter WrayNCT02966665Written as BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate
- Effect of Tocopherol and Ascorbic Acid on Neuroinflammation Markers Associated With Neuropeptide Expression in the AgRP/NPY and POMC Pathways in Mexican Population With ObesityNot yet recruitingNot applicableAutonomous University of MorelosNCT07782411Written as Ascorbic acid (Vitamin C)
- NCT + PD1 + Ketogenic Diet and/or Vitamin C for LARCNot yet recruitingPhase 2Sixth Affiliated Hospital, Sun Yat-sen UniversityNCT07765667Written as Vitamin C
- A Study of CA201A Eye Drops to Prevent Corneal Endothelial Cell Loss in Patients Undergoing Cataract SurgeryRecruitingPhase 2Caravel Oculus Pty LtdNCT07694375Written as Ascorbic acid ophthalmic solution 5%
- Antidepressant Therapy for Improved Blood Vessel Health After PreeclampsiaRecruitingEarly Phase 1Anna Stanhewicz, PhDNCT07715669Written as Ascorbic acid (Vitamin C)
- Effect of Co-enzyme Q10 and Vitamin C Alone or in Combination After a Surgical Gingival DepigmentationRecruitingNot applicableAl-Azhar UniversityNCT07677826Written as Vitamin C
- Perioperative Vitamin C to Reduce Persistent Pain After Total Knee ArthroplastyRecruitingPhase 2University Health Network, TorontoNCT06123715Written as Vitamin C
- High-Dose Vitamin C in G6PDA and Pyruvate Kinase Deficiency: A Safety StudyNot yet recruitingPhase 1University of UtahNCT07612345Written as Vitamin C
- Gingival Hyperpigmentation TreatmentRecruitingPhase 2Cairo UniversityNCT07595705Written as Vitamin c and glutathione
- Comparing Three Rescue Bowel Preparation Regimens for Colonoscopy After Failed CleansingRecruitingNot applicableOspedale San PioNCT07557173Written as Drug
- Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.Not yet recruitingNot applicableNicosia General HospitalNCT06995586Written as Vitamin C, Omega 3 PUFA (EPO/DHA), Lignin, Lactulose
- Impact of Vitamin C on opioïd Consumption After an Emergency Department Visit for Acute Musculoskeletal PainRecruitingNot applicableCentre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de MontrealNCT05555576Written as Vitamin C
- Vitamin C for Acute Kidney Injury in ACLF With Septic Shock: A Randomized Controlled TrialNot yet recruitingNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT07184866Written as Vitamin C
See all 408 studies that test Ascorbic Acid →
Given in every arm · 19 — Ascorbic Acid is usual care beside what is tested
- Reversing Glucose and Lipid-mediated Vascular DysfunctionRecruitingEarly Phase 1University of Kansas Medical CenterNCT04832009Written as Ascorbic acid
- Reducing Frailty for Older Cancer Survivors Using Supplements IISuspendedPhase 2University of RochesterNCT06068543Written as Ascorbic Acid (Vitamin C)
- The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent ClaudicationActive, not recruitingPhase 1Louis MessinaNCT04800692Written as L-Ascorbate
- A Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 InfectionCompletedPhase 2ProgenaBiomeNCT04335084Written as Vitamin C
- Daily vs. Every Other Day Oral Iron Supplementation in Patients With Absolute Iron Deficiency AnemiaCompletedPhase 3Sunnybrook Health Sciences CentreNCT03725384Written as Vitamin C 500Mg tablet
- Phase II Study of PARP Inhibitor Olaparib and IV Ascorbate in Castration Resistant Prostate CancerTerminatedPhase 2Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT05501548Written as Vitamin C
- Trial of Combination Therapy to Treat COVID-19 InfectionCompletedPhase 1ProgenaBiomeNCT04482686Written as Vitamin C
- A Study of Quintuple Therapy to Treat COVID-19 InfectionCompletedPhase 2ProgenaBiomeNCT04334512Written as Vitamin C
- Investigating the Role of Diazepam on Brain Function and Chemistry in Psychosis RiskCompletedNot applicableKing's College LondonNCT06190483Written as Ascorbic Acid 50 Mg Oral Tablet
- A Pilot Study To Evaluate the Effects of Lactobacillus SupplementsCompletedNot applicableSeoul National University HospitalNCT05520073Written as Vitamin C
- Phosphate Lowering in CKD TrialCompletedPhase 4VA Office of Research and DevelopmentNCT02209636Written as Ascorbic Acid
- A Phase I Study of High-dose L-methylfolate in Combination With Temozolomide and Bevacizumab in Recurrent High Grade GliomaCompletedPhase 1Vanderbilt-Ingram Cancer CenterNCT01891747Written as Vitamin C
- Treatment of Pulmonary Fibrosis Due to COVID-19 With Fuzheng HuayuCompletedPhase 2ShuGuang HospitalNCT04279197Written as Vitamin C tablets
- Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19CompletedNot applicableUnidad Temporal COVID-19 en Centro CitibanamexNCT04570254Written as Vitamin C
- Velcade, Trisenox, Vitamin C and Melphalan for Myeloma PatientsCompletedPhase 1/2M.D. Anderson Cancer CenterNCT00469209Written as Vitamin C (Ascorbic Acid)
- Impact of Low Fiber Diet on Colonic Cleansing Quality (DIETPREP)CompletedNot applicableHospital Universitario de CanariasNCT03247452Written as Polyethylene Glycol plus ascorbic acid
- Vitamin Deficiency and Blood Pressure in Hospitalized Jewish General Hospital (JGH) PatientsCompletedPhase 2Jewish General HospitalNCT00921622Written as Vitamin C
- Tetrahydrobiopterin in Patients With Chronic Kidney Disease (CKD) and AlbuminuriaCompletedPhase 2University of MichiganNCT00625820Written as Vitamin C
- Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and StatinsCompletedNot applicableUS Department of Veterans AffairsNCT00995670Written as Vitamin C
As the comparator · 19 — what is tested is compared with Ascorbic Acid
- Efficacy and Safety of mAnnitol in Bowel Preparation During Elective Colonoscopy and Comparison With Moviprep®CompletedPhase 2/3NTC srlNCT04759885Written as Phase III: Polyethylene glycol plus ascorbate solution (2L PEG ASC)
- Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency DepartmentsCompletedPhase 3Universitaire Ziekenhuizen KU LeuvenNCT04747795Written as Vitamin C
- Use of a Combined Regimen of Fluoxetine, Prednisolone and Ivermectin in the Treatment of Mild COVID-19 to Prevent Disease Progression Progression in Papua New GuineaWithdrawnPhase 2/3Oriol MitjaNCT05283954Written as Combination regimen: Albendazole, Vitamin C
- Gastrointestinal Tolerance Assessment of T2309CompletedNot applicableLaboratoires TheaNCT04596605Written as Nutrof Total
- Efficacy and Tolerability of Apevitin BC Comparing to Vitamin Complex in Stimulating the AppetiteCompletedPhase 3EMSNCT01283646Written as Vitamin B Complex + Vitamin C
- Intravenous Iron Isomaltoside Versus Oral Iron Supplementation for Treatment of Iron Deficiency in Pregnancy.CompletedPhase 4Pharmacosmos A/SNCT03188445Written as ferrous fumarate with ascorbic acid
- A Preventive Treatment for Migrant Workers at High-risk of COVID-19CompletedPhase 3National University Hospital, SingaporeNCT04446104Written as Vitamin C
- Impact of a Nutritional Supplement on the Recovery of the Nutritional Status of Patients With Spontaneous Hip FractureStatus unknownNot applicableLaboratorios OrdesaNCT04183075Written as Carbohydrates and C Vitamin
- Hydroxychloroquine in Patients With Newly Diagnosed COVID-19 Compared to Standard of CareSuspendedPhase 4Providence Health & ServicesNCT04334967Written as Vitamin C
- Impact of a Predictive Score of Bowel Preparation Quality in Clinical PracticeCompletedPhase 4Hospital Universitario de CanariasNCT03830489Written as polyethylene glycol plus ascorbic acid
- Compare Effects of EpiCor and Vitamin C to Vitamin C Alone on the Common Cold or Influenza in Healthy ChildrenCompletedNot applicableCargillNCT04093206Written as Vitamin C
- A Study to Demonstrate the Efficacy and Tolerability of Ferrous Bisglycinate Chelate in Iron Deficiency Anaemia and to Compare These With Those of Ferrous Ascorbate.CompletedPhase 3GlaxoSmithKlineNCT01160198Written as ferrous ascorbate
- COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS)CompletedPhase 2Spherium BiomedNCT03223519Written as Vitamin C
- Oxidative Stress and Opiorphin in Temporomandibular DisordersStatus unknownNot applicableCroatian Science FoundationNCT03029494Written as Vitamin C
- Comparative Study on the Effects of Sublingual Misoprostol in Addition to Standard AMTSL in Low Risk Parturients in LASUTH, Ikeja.Status unknownEarly Phase 1Lagos State UniversityNCT02424201Written as vitamin c
- Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School ChildrenCompletedNot applicableLondon School of Hygiene and Tropical MedicineNCT01658774Written as Vitamin C
- The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal CancerStatus unknownPhase 2/3Taichung Veterans General HospitalNCT01426490Written as Vitamin C
- Comparative Bioavailability of Two Forms of Vitamin CCompletedNot applicableNBTY, Inc.NCT01852903Written as ascorbic acid
- Effect of Vitamin D Supplementation on Hemoglobin A1c in Patients With Uncontrolled Type 2 Diabetes MellitusCompletedNot applicableProMedica Health SystemNCT00985361Written as Vitamin C 500mg daily
Codes
What other systems call Ascorbic Acid · ClinicalTrials.gg INT007026
- MeSH (NLM) D001205Ascorbic AcidConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) PQ6CK8PD0RASCORBIC ACIDConfirmed FDA, NLM
- RxNorm 1151One source FDA
- NCI Thesaurus C285Ascorbic AcidOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D001205 | Ascorbic Acid | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | PQ6CK8PD0R | ASCORBIC ACID | Confirmed FDA, NLM |
| RxNorm | 1151 | — | One source FDA |
| NCI Thesaurus | C285 | Ascorbic Acid | One source FDA |
Also registered as ferrous ascorbate (UNII DI3477D0PI · RxNorm 4356), magnesium ascorbate (UNII 0N1G678593 · RxNorm 1311396) and sodium ascorbate (UNII S033EH8359 · RxNorm 267366).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.