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Systemic Inflammatory Response Syndrome clinical trials

The registry lists 195 studies for Systemic Inflammatory Response Syndrome across more than 10 countries. 24 are recruiting or about to start. 77 of them are mainly about Systemic Inflammatory Response Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 11 narrower conditions too, such as Sepsis: 3,810 studies, 787 open.

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Status

Completed
108
Status unknown
37
Recruiting
20
Terminated
16
Active, not recruiting
7
Not yet recruiting
4

Phase

Phase 2
24
Phase 4
18
Phase 3
10
Phase 1
9
Early Phase 1
1

Where

United States
39
Germany
19
China
17
France
17
Denmark
13
Spain
11

Who runs them

Rigshospitalet, Denmark (5) · University of Ulm (4) · Chinese PLA General Hospital (3) · UMC Utrecht (3) · Christian Hassager (3) · Ain Shams University (3) · Careggi Hospital (3) · Bluejay Diagnostics, Inc. (3)

What is being tested here

Drugs under test in Systemic Inflammatory Response Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Methylprednisolone105
Hydrocortisone102
Dexmedetomidine101
Sivelestat101
Angiotensin II101
Hydrocortisone hemisuccinate101
Dexamethasone014
Zegocractin002
Rezafungin022
Vilobelimab002

Drug classes tested here Corticosteroids 2 open

Coming up

1phase 3 study under way
8studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 8, phase 3 first

Who these studies take

Of the 20 Systemic Inflammatory Response Syndrome studies recruiting now, 13 (65%) set no upper age limit and 4 (20%) stop at 75 or younger. 5 (25%) take children under 18. 0 (0%) are for women only and 1 (5%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 20
AgeWomenMen
105 (25%)5 (25%)
1818 (90%)18 (90%)
3017 (85%)17 (85%)
4017 (85%)17 (85%)
5017 (85%)18 (90%)
6517 (85%)18 (90%)
7516 (80%)17 (85%)
8515 (75%)15 (75%)

Across all 195 studies, recruiting or not: 20% stop at 75 or younger and 14% at 65; 14% take children; 1% are for women only and 2% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Systemic Inflammatory Response Syndrome studies take

Of 47 observational studies under Systemic Inflammatory Response Syndrome, half reached primary completion within 31 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Observational31 mo14–55 · 47 studies—31 mo16–55 · 42 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

Studies

Recruiting first, then most recently updated. Showing 50 of 195. Browse all 195 → or search them.