Drug
Hydrocortisone clinical trials
Also written Cortef, Cortisol, Hydrocortone and NSC-10483.
Includes 5 studies of Hydrocortisone acetate.
- studies test it
- 226
- open now
- 26
- in phase 3
- 54
- first study started
- 1992
Keep track of what changes. Save the Hydrocortisone studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Other names
- Cortisol
- 12
Studies by the year they started
226 studies that test it; most in 2016 (17)
| Year | Studies |
|---|---|
| 1992 | 1 |
| 1996 | 6 |
| 1997 | 1 |
| 1999 | 1 |
| 2000 | 3 |
| 2001 | 1 |
| 2002 | 3 |
| 2003 | 3 |
| 2004 | 3 |
| 2005 | 6 |
| 2006 | 5 |
| 2007 | 8 |
| 2008 | 16 |
| 2009 | 13 |
| 2010 | 8 |
| 2011 | 5 |
| 2012 | 11 |
| 2013 | 8 |
| 2014 | 14 |
| 2015 | 11 |
| 2016 | 17 |
| 2017 | 9 |
| 2018 | 10 |
| 2019 | 10 |
| 2020 | 8 |
| 2021 | 7 |
| 2022 | 12 |
| 2023 | 5 |
| 2024 | 6 |
| 2025 | 6 |
| 2026 | 9 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 15
- Phase 1
- 29
- Phase 2
- 60
- Phase 3
- 54
- Phase 4
- 50
- No phase
- 36
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 29 · Other 197
Neurocrine UK Limited (16) · St. Jude Children's Research Hospital (6) · Ain Shams University (5) · Children's Oncology Group (5) · Hospital for Special Surgery, New York (4) · LEO Pharma (4) · Haukeland University Hospital (4) · Beth Israel Deaconess Medical Center (4)
Often tested with
Tested in the same studies.
Methotrexate (18) · Cytarabine (16) · Dexamethasone (14) · Cyclophosphamide (11) · Etoposide (11) · Vincristine (9) · Prednisone (9) · Ketoconazole (8)
Studies
Open first, then newest update. How each study uses Hydrocortisone is read from its arms, and is right about nine times in ten.
Testing it · 226
- Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Exploratory, Bayesian Basket TrialRecruitingPhase 2Assistance Publique - Hôpitaux de ParisNCT06381661Written as Hydrocortisone
- Sleep Loss and Circadian Misalignment - Mechanisms of Insulin ResistanceRecruitingPhase 4Washington State UniversityNCT07494084Written as Metyrapone And Hydrocortisone
- GI-06: The Impact of Perioperative Hydrocortisone on Patients Undergoing Partial PancreatectomyNot yet recruitingPhase 1University of Illinois at ChicagoNCT07796997Written as Hydrocortisone
- Imaging CRF X NOP Interactions in CUDRecruitingEarly Phase 1Rajesh NarendranNCT05008146Written as Hydrocortisone
- Intrathecal Cytarabine, Methotrexate, and Hydrocortisone for the Prevention of High-Grade Chimeric Antigen Receptor T-Cell-Associated Neurotoxicity SyndromeRecruitingPhase 2OHSU Knight Cancer InstituteNCT06895473Written as Therapeutic Hydrocortisone
- Imaging CRF X NOP Interactions in Alcohol Use DisorderRecruitingEarly Phase 1Rajesh NarendranNCT07612631Written as Hydrocortisone
- Hydrocortisone Plus Fludrocortisone in High-risk Patients Undergoing for Cardiac SurgeryRecruitingPhase 3Centre Hospitalier Universitaire, AmiensNCT07037043Written as hydrocortisone plus fludrocortisone
- The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance OutcomesRecruitingPhase 4Walter Reed Army Institute of Research (WRAIR)NCT06982183Written as Hydrocortisone
- Hydrocortisone Therapy Optimization During Hypothermia Treatment in Asphyxiated NeonatesRecruitingPhase 4Semmelweis UniversityNCT05836610Written as Hydrocortisone
- Sore Throat After Open Neck Elective SurgeryRecruitingPhase 4Saint Petersburg State University, RussiaNCT07124650Written as Hydrocortisone Acetate 1% Ointment
- Comparing Hydrocortisone and Prednisolone for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)RecruitingPhase 4Copenhagen Respiratory ResearchNCT06892210Written as Hydrocortisone
- Comparing Hydrocortisone and Prednisolone for Community Acquired Pneumonia (CAP)RecruitingPhase 4Copenhagen Respiratory ResearchNCT06892197Written as hydrocortisone
- Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal InsufficiencyRecruitingPhase 4Marianne Christina KloseNCT05435781Written as Hydrocortisone
- Hydrocortisone and Fludrocortisone for the Treatment of Septic ShockRecruitingPhase 4Northern Jiangsu People's HospitalNCT07383103Written as Hydrocortisone plus Fludrocortisone
- Corticosteroids to Treat PancreatitisRecruitingPhase 2Beth Israel Deaconess Medical CenterNCT05160506Written as Hydrocortisone
- Effects of Pharmacological Stress and rTMS on Executive Function in Opioid Use DisorderNot yet recruitingPhase 2Wayne State UniversityNCT04231708Written as Yohimbine + Hydrocortisone
- Hydrocortisone and Placebo in Patients With Symptoms of Adrenal Insufficiency After Cessation of Glucocorticoid TreatmentRecruitingPhase 4Marianne AndersenNCT05193396Written as Hydrocortisone
- Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA)RecruitingPhase 4Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NCT07262957Written as HOP bundle
- Stress Hydrocortisone In Pediatric Septic ShockRecruitingPhase 3Jerry ZimmermanNCT03401398Written as Hydrocortisone, sodium succinate
- Congenital Adrenal Hyperplasia Once Daily Hydrocortisone TreatmentRecruitingPhase 4Federico II UniversityNCT03760835Written as Dual release hydrocortisone (plenadren)
See all 226 studies that test Hydrocortisone →
Given in every arm · 76 — Hydrocortisone is usual care beside what is tested
- Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged LeukemiaRecruitingPhase 2National Cancer Institute (NCI)NCT06317662Written as Therapeutic Hydrocortisone
- A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)RecruitingPhase 3Merck Sharp & Dohme LLCNCT06136650Written as Hydrocortisone
- Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+) or ABL-class Ph-like Acute Lymphoblastic Leukemia (ALL)RecruitingPhase 1/2Novartis PharmaceuticalsNCT07387926Written as Hydrocortisone (intrathecal)
- Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)RecruitingPhase 3Merck Sharp & Dohme LLCNCT06136624Written as Hydrocortisone
- Intrathecal Cytarabine and Hydrocortisone for the Early Treatment of ICANS in Patients Undergoing CAR T Therapy for Non Hodgkin LymphomaRecruitingPhase 2Vanderbilt-Ingram Cancer CenterNCT07763210Written as Therapeutic Hydrocortisone
- A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 MutationsRecruitingPhase 3Children's Oncology GroupNCT04293562Written as Therapeutic Hydrocortisone
- Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL)Not yet recruitingPhase 2/3Children's Oncology GroupNCT07072585Written as Therapeutic Hydrocortisone
- Trial of Revumenib Plus FLA Chemotherapy for Children With Relapsed or Refractory NUP98-rearranged AML."Not yet recruitingPhase 2Therapeutic Advances in Childhood Leukemia ConsortiumNCT07686107Written as Hydrocortisone (intrathecal)
- Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post ConsolidationRecruitingEarly Phase 1C17 CouncilNCT06942039Written as hydrocortisone
- Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2)RecruitingPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT06504160Written as Hydrocortisone Ointment
- Venetoclax Basket Trial for High Risk Hematologic MalignanciesRecruitingPhase 1Andrew E. Place, MDNCT05292664Written as Hydrocortisone
- Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic MalignanciesRecruitingPhase 1Therapeutic Advances in Childhood Leukemia ConsortiumNCT05476770Written as Hydrocortisone
- Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic LeukemiaActive, not recruitingPhase 3National Cancer Institute (NCI)NCT02101853Written as Therapeutic Hydrocortisone
- Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and NavitoclaxActive, not recruitingPhase 1/2St. Jude Children's Research HospitalNCT05192889Written as Intrathecal Triples
- Study of CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary Myeloid NeoplasmsActive, not recruitingPhase 2St. Jude Children's Research HospitalNCT05656248Written as MHA
- Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid LeukemiaActive, not recruitingPhase 1St. Jude Children's Research HospitalNCT04898894Written as methotrexate/hydrocortisone/cytarabine
- Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaActive, not recruitingPhase 3Children's Oncology GroupNCT03007147Written as Therapeutic Hydrocortisone
- Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe SepsisWithdrawnPhase 4CAMC Health SystemNCT00368381Written as Hydrocortisone
- 05-001: Treatment of Acute Lymphoblastic Leukemia in ChildrenCompletedPhase 3Dana-Farber Cancer InstituteNCT00400946Written as therapeutic hydrocortisone
- ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016Active, not recruitingPhase 2National Hospital Organization Nagoya Medical CenterNCT03286634Written as Hydrocortisone
Showing 20 of 76.
As the comparator · 16 — what is tested is compared with Hydrocortisone
- Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and AdolescentsActive, not recruitingPhase 3Dana-Farber Cancer InstituteNCT03020030Written as HYDROCORTISONE
- StrataXRT for the Prevention and Treatment of Radiation Dermatitis in Breast Cancer or Head and Neck Cancer PatientsWithdrawnNot applicableOHSU Knight Cancer InstituteNCT05073172Written as Topical Hydrocortisone
- Effect of Slow Release Hydrocortisone on Fed & Fasting Volunteers; Immediate Release on Fasting OnlyCompletedPhase 1Neurocrine UK LimitedNCT02408068Written as Immediate release hydrocortisone: fasted
- Medihoney® Derma Cream Treatment for Mild to Moderate Atopic Dermatitis in Children StudyCompletedPhase 2Soroka University Medical CenterNCT05276323Written as Hydrocortisone 1% cream
- Tapioca Starch Stimutex AS, Aloe Barbadensis, Rose Hip Oil, Allantoin Comparing With Topical 1% Hydrocortisone CreamCompletedPhase 4Mahidol UniversityNCT04325490Written as Hydrocortisone cream 1%
- Hydrocortisone Use During Peri-operation for Pituitary AdenomasStatus unknownNot applicablePeking Union Medical College HospitalNCT04621565Written as Hydrocortisone
- Topical Cream SNG100 for Treatment in Moderate Atopic Dermatitis Subjects.Status unknownPhase 1Seanergy Dermatology Ltd.NCT04615962Written as Hydrocortisone Acetate 1% Cream
- Spironolactone in Preventing Rash in Patients With Advanced Cancer Receiving Panitumumab and CetuximabCompletedPhase 2Academic and Community Cancer Research UnitedNCT01867294Written as Therapeutic Hydrocortisone
- Endoscopic Treatment of Salivary Glands Affected by Sjögren's SyndromeStatus unknownNot applicableDerk Jan JagerNCT02112019Written as hydrocortisone
- Oregano Ointment vs. Standard Treatment for Pediatric Atopic DermatitisTerminatedNot applicableRutgers, The State University of New JerseyNCT02289989Written as Hydrocortisone
- Modified-release Compared to Conventional Hydrocortisone on Diurnal Fatigue in Secondary HypoadrenalismStatus unknownPhase 4Ulla Feldt-RasmussenNCT02282150Written as Hydrocortisone
- Evaluation of Efficacy of Aloevera in the Treatment of Oral Submucous Fibrosis- A Clinical StudyCompletedPhase 3The Oxford Dental College, Hospital and Research Center, Bangalore, IndiaNCT02714543Written as Hydrocortisone
- Equivalence of the Response to Vaccination of Tacrolimus Ointment to a Steroid Ointment Regimen in Children With Atopic DermatitisCompletedPhase 2Astellas Pharma IncNCT00801957Written as hydrocortisone acetate ointment 1%
- Corticosteroids for the Prevention of Atrial Fibrillation After Cardiac SurgeryTerminatedNot applicableKuopio University HospitalNCT00442494Written as intravenous hydrocortisone
- Ultra Violet B Radiation (UVR) Study of Strontium Chloride Hexahydrate HydrocortisoneCompletedPhase 1X-pert Med GmbHNCT01301677Written as Hydrocortisone
- Effect of Etomidate on Hemodynamics and Adrenocortical Function After Cardiac SurgeryCompletedPhase 4Insel Gruppe AG, University Hospital BernNCT00415701Written as Hydrocortisone
Codes
What other systems call Hydrocortisone · ClinicalTrials.gg INT007628
- MeSH (NLM) D006854HydrocortisoneConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) WI4X0X7BPJHYDROCORTISONEConfirmed FDA, NLM
- RxNorm 5492One source FDA
- NCI Thesaurus C555Therapeutic HydrocortisoneOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D006854 | Hydrocortisone | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | WI4X0X7BPJ | HYDROCORTISONE | Confirmed FDA, NLM |
| RxNorm | 5492 | — | One source FDA |
| NCI Thesaurus | C555 | Therapeutic Hydrocortisone | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.