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Pain, Intractable clinical trials

The registry lists 90 studies for Pain, Intractable across more than 10 countries. 16 are recruiting or about to start. 50 of them are mainly about Pain, Intractable (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Completed
39
Terminated
14
Status unknown
11
Recruiting
11
Withdrawn
6
Not yet recruiting
4

Phase

Phase 3
11
Phase 2
10
Phase 4
7
Phase 1
5
Early Phase 1
1

Where

United States
39
France
13
Canada
7
Spain
7
Italy
4
Germany
4

Who runs them

MedtronicNeuro (5) · Boston Scientific Corporation (4) · Abbott Medical Devices (4) · Assistance Publique - Hôpitaux de Paris (3) · Flowonix Medical (3) · Rush University Medical Center (2) · Vanderbilt University Medical Center (2) · Sorrento Therapeutics, Inc. (2)

What is being tested here

Drugs under test in Pain, Intractable studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Resiniferatoxin114
Ketamine034
Propofol012
Dexmedetomidine012
Fentanyl012
Methadone022
Bupivacaine001
Pregabalin001
Buprenorphine001
Naloxone001

Drug classes tested here Opioids 6

Coming up

0phase 3 studies under way
8studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 8

Who these studies take

Of the 11 Pain, Intractable studies recruiting now, 8 (73%) set no upper age limit and 1 (9%) stop at 75 or younger. 1 (9%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 11
AgeWomenMen
101 (9%)1 (9%)
1810 (91%)10 (91%)
3011 (100%)11 (100%)
4011 (100%)11 (100%)
5011 (100%)11 (100%)
6511 (100%)11 (100%)
7510 (91%)10 (91%)
8510 (91%)10 (91%)

Across all 90 studies, recruiting or not: 17% stop at 75 or younger and 10% at 65; 4% take children; 0% are for women only and 0% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Pain, Intractable studies take

Of 26 interventional studies with no phase under Pain, Intractable, half reached primary completion within 24 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase24 mo20–34 · 26 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Results posted1

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 90. Browse all 90 → or search them.