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CompletedNCT06537375Updated Feb 25, 2025

Use of Ketamine in Severe Pain Syndromes

An observational study in Pain, Intractable, Pain, Chronic and Pain Syndrome, sponsored by Erasme University Hospital. Completed at 1 site in Belgium. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-02-25.

Sponsored by Erasme University Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
89
Ages
18 Years and older
Sex
All
01

Study summary

Ketamine has been shown to have a certain efficiency in chronic pain syndromes. However, it is still not clearly known what is its efficiency and how ketamine is used in real world patients. In this retrospective study, all patients treated with ketamine for chronic pain in our hospital will be reviewed. Patients demographics, pain syndromes as well as outcome criteria will be collected to describe the use of ketamine in pain syndromes.

Read the detailed description

The American Society of Regional Anesthesia and Pain Medicine, together with the American Academy of Pain and the American Society of Anesthesiologists published a consensus guideline in 2018 on the use of ketamine in chronic pain. A review of medical charts of all patients who received ketamine for chronic pain between january 2010 and june 2024 will be done. Demographic data, detailed pain scores, as well as description of the type of pain will be collected. Ketamine usage will be recorded for the dosage, as well as duration of the treatment. Outcome will be measured by before/after pain scores for neuropathic pain, as well as on a visual analog scale. A more global score (good-medium-no effect) will also be collected to get the patient's impression on their treatment. Concomitant pain medication will be collected.

02

Conditions studied

  • Pain, Intractable
  • Pain, Chronic
  • Pain Syndrome
  • Pain Measurement
03

In context

Pain, Intractable

90 studies on the registry are indexed under Pain, Intractable; 16 are open to participants now.

This study's enrollment of 89 is close to the median of 91 across 19 observational studies indexed under Pain, Intractable.

Browse Pain, Intractable studies →

Lead sponsor

Erasme University Hospital is the lead sponsor of 181 studies on the registry; 35 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All patients who received ketamine as treatment for a pain syndrome during january 2010 until june 2024 at Erasme University Hospital

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • All patients who received ketamine as treatment for a pain syndrome during january 2010 until june 2024 at Erasme University Hospital

Exclusion criteria

Exclusion Criteria:

  • Age \< 18 years
  • Patients who expressed their opposition to the use of their medical data
  • incomplete medical chart
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
89 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Patient satisfaction

    A scale (good-medium-no effect) of the efficacity of ketamine on their pain syndrome

    Time frame: 6 month

  2. DN4

    Neuropathic pain scale 4

    Time frame: 6 month

  3. VAS

    Visual analog scale of the pain intensity

    Time frame: 6 month

Secondary outcomes

  1. Concomitant pain medications

    Number of concomitant pain medications used by the patient

    Time frame: 6 month

07

Study locations

1 site
  • Hôpital Universitaire de Bruxelles - Hôpital erasme
    Brussels, 1070, Belgium
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Aug 2024 to primary completion in Feb 2025, 6 months.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 1, 2024
First posted
Aug 5, 2024
StartActual
Aug 1, 2024
Primary completionActual
Feb 20, 2025
CompletionActual
Feb 20, 2025
Last update
Feb 25, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Feb 25, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06537375
Responsible party
Sponsor
First posted
Aug 5, 2024
Start date
Aug 1, 2024
Primary completion
Feb 20, 2025
Completion
Feb 20, 2025
Last update
Feb 25, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2024. You cannot join it, but the record below documents what was studied.

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Discussion

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