Parkinson Disease clinical trials
The registry lists 4,576 studies for Parkinson Disease across more than 10 countries. 1,087 are recruiting or about to start. 4,103 of them are mainly about Parkinson Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
ClinicalTrials.gov finds 5,071 studies for Parkinson Disease. How that becomes 4,569 here
This page counts the studies the registry files under Parkinson Disease, and those it files under no condition that list Parkinson Diseasethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 5,071Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −48List Parkinson Disease as a condition, but the registry did not file them under itMost often written as “Parkinson Disease Dementia” (10), “Parkinson's Disease Dementia” (6), and “Advanced Parkinson's Disease” (5). The registry filed them under other conditions only, most often Lewy Body Disease (21) and Alzheimer Disease (12).
- −454Match it another way130 name it in the title, 8 in a keyword, and 316 by a synonym or other text the search reads.
- 4,569The count on this page78 of them list Parkinson Disease in their own words; the registry filed them under no condition.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
National Institute of Neurological Disorders and Stroke (NINDS) (63) · Bial - Portela C S.A. (57) · VA Office of Research and Development (43) · Boehringer Ingelheim (42) · University of Florida (41) · Oregon Health and Science University (36) · AbbVie (35) · Radboud University Medical Center (34)
What is being tested here
Drugs under test in Parkinson Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Levodopa | 3 | 9 | 48 |
| Lidocaine | 3 | 0 | 3 |
| Prasinezumab | 2 | 1 | 6 |
| Ambroxol | 2 | 2 | 6 |
| IPX203 | 2 | 2 | 5 |
| Terazosin | 2 | 1 | 5 |
| Ketamine | 2 | 0 | 4 |
| Lu AF28996 | 2 | 0 | 4 |
| Metformin | 2 | 2 | 3 |
| Psilocybin | 2 | 0 | 3 |
Drug classes tested here Local anesthetics 3 open · Dopamine agonists 2 open · Cholinesterase inhibitors 2 open · Serotonin receptor agonists 2 open · Antipsychotics 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Vinpocetine in Patients With Parkinsonian Disease · Phase 3 · Tanta University
- Nov 2026Metformin in Parkinson Disease · Phase 3 · Tanta University
- Dec 2026Fexofenadine as Adjuvant Therapy in Parkinson Disease · Phase 3 · Tanta University
- Jul 2027Pharmacologically Modulating the Noradrenergic Arousal System to Reduce Freezing of Gait in Parkinson's Disease: a Multi-centre and Multi-modal Approach · Phase 3 · Radboud University Medical Center
- Aug 2027A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease · Phase 3 · Biohaven Therapeutics Ltd.
- Oct 2027VG081821AC Tablets for Early to Mid-stage Parkinson's Disease · Phase 3 · Zhejiang Vimgreen Pharmaceuticals, Ltd.
- Nov 2026Cerebellar Transcranial Direct Current Stimulation in Parkinson's Disease · Université Libre de Bruxelles
- Nov 2026Synthetic Vasomotion for Glymphatic Enhancement · Florida Institute for Human and Machine Cognition
- Nov 2026Pilot Study of Robotic Spinal Mobilization in Parkinson's Disease · Pacla Medical Limited
- Nov 2026Effects of the Stimulation Site of tsMS With TMS on Functional Mobility in Individuals With Parkinson's Disease · Universidade Federal de Pernambuco
Who these studies take
Of the 749 Parkinson Disease studies recruiting now, 311 (42%) set no upper age limit and 127 (17%) stop at 75 or younger. 64 (9%) take children under 18. 2 (<1%) are for women only and 3 (<1%) for men only; 189 (25%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 61 (8%) | 61 (8%) |
| 18 | 364 (49%) | 363 (48%) |
| 30 | 459 (61%) | 457 (61%) |
| 40 | 586 (78%) | 584 (78%) |
| 50 | 729 (97%) | 727 (97%) |
| 65 | 737 (98%) | 739 (99%) |
| 75 | 689 (92%) | 688 (92%) |
| 85 | 469 (63%) | 468 (62%) |
Across all 4,576 studies, recruiting or not: 18% stop at 75 or younger and 4% at 65; 9% take children; <1% are for women only and 1% for men only; 22% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Parkinson Disease studies take
Of 204 phase 1 interventional studies under Parkinson Disease, half reached primary completion within 19 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 19 mo5–40 · 204 studies | 9 mo3–24 · 127 studies | 37 mo20–68 · 77 studies |
| Phase 1/2 | 25 mo12–53 · 55 studies | — | — |
| Phase 2 | 28 mo16–44 · 201 studies | 19 mo13–33 · 96 studies | 35 mo24–59 · 105 studies |
| Phase 2/3 | 22 mo18–50 · 22 studies | — | — |
| Phase 3 | 35 mo22–56 · 67 studies | 31 mo20–54 · 39 studies | — |
| Phase 4 | 28 mo19–65 · 56 studies | — | 41 mo21–75 · 41 studies |
| Interventional, no phase | 25 mo12–44 · 1,369 studies | 27 mo17–43 · 76 studies | 24 mo11–44 · 1,293 studies |
| Observational | 47 mo22–114 · 439 studies | 37 mo19–64 · 60 studies | 48 mo22–133 · 379 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting12
- Study to Test Effects and Safety of RO7568282 in Early Parkinson's DiseaseNov 9, 2026NCT07781644
- Phase I/II Clinical Trial of UX-DA003 Injection for the Treatment of Patients With Parkinson's DiseaseNov 4, 2026NCT07733349
- Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced DevicesNov 3, 2026NCT07066137
- Effects of Microelectrode-based Brain Stimulation in HumansNov 3, 2026NCT07820189
- Investigating Basal Ganglia-Cortical Physiology During Sleep and Its Modulation by Adaptive Deep Brain Stimulation in Parkinson DiseaseOct 30, 2026NCT07808346
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- Investigating the Increased Risk of Falls in Individuals With Parkinson's Disease Treated With Deep Brain StimulationOct 26, 2026NCT07725315
- Decoding the Neural Mechanisms Underlying Postural Instability and Gait Dysfunction in Parkinson's DiseaseOct 26, 2026NCT07748962
- Prevent Cognitive Decline in GBA-associated Parkinson's DiseaseOct 23, 2026NCT07055087
- MediPD: An Online Mediterranean Diet Program for People Living With Parkinson's DiseaseOct 21, 2026NCT07838675
- Dual Tasking Training to Enhance Self-Efficacy in Individuals With Parkinson's DiseaseOct 20, 2026NCT07611578
- Efficacy of a Prediction Model-based Algorithm to PREVENT Drug-induced Impulse Control Disorders in Parkinson's DiseaseOct 16, 2026NCT07505394
- Assessment of the Rehabilitative Effects of Curved-walking Training in Stroke, Parkinson and Orthopaedic PopulationsOct 15, 2026NCT03545477
Results posted4
- Efficacy, Safety and Pharmacokinetic Study of CPL500036 in Patients With Levodopa Induced DyskinesiaNov 12, 2026NCT05297201
- Mobility in Daily Life and Falls in Parkinson's Disease: Potential for RehabilitationNov 6, 2026NCT04897256
- Robotic Gait Rehabilitation in Parkinson's DiseaseNov 5, 2026NCT05218187
- Cortical Network Modulation by Subthalamic Nucleus DBSOct 21, 2026NCT04922411
Stopped6
- The Efficacy and Safety Study of High Dose Donepezil in Parkinson's Disease With DementiaTerminatedNov 10, 2026NCT02415062
- The Effect of Transcranial Direct Current Stimulation (tDCS) on Depression in PDWithdrawnNov 10, 2026NCT03227783
- High-Dose Ambroxol in GBA1-Related ParkinsonTerminatedNov 9, 2026NCT06193421
- Tapping Test and the Archimedean Spiral for the Differential Diagnosis of Tremor. Machine Learning ApproachTerminatedOct 28, 2026NCT06378619
- Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic FailureTerminatedOct 23, 2026NCT02897063
Show 1 moreShow fewer
- Observational Small Intestine and Blood Fingerprint (SmIle) Study in Parkinson's DiseaseTerminatedOct 20, 2026NCT06003608
Newly registered35
- Virtual Reality for Motor and Cognitive Function in People With Parkinson's DiseaseNov 12, 2026NCT07931040
- Identification of Cognitive and Motor Changes in Individuals With and Without Parkinson's Disease Using HemoencephalographyNov 12, 2026NCT07931677
- Expiratory Muscle Strength Training for People With Parkinson's DiseaseNov 12, 2026NCT07932561
- RehaBEElitation - Serious Game-Based Experimental Protocol to Improve Manual Dexterity in Individuals With Parkinson's DiseaseNov 10, 2026NCT07928050
- Training in Adults With Parkinson's DiseaseNov 10, 2026NCT07928609
Show 30 moreShow fewer
- A Phase 1/2a Clinical Study of KL002 in Treatment of Parkinson's DiseaseNov 10, 2026NCT07929480
- Magnetic-Resonance Guided Focused Ultrasound Pallidothalamic Tractotomy for Parkinson's DiseaseNov 9, 2026NCT07925086
- Effects of Transcranial Direct Current Stimulation Combined With Nordic Walking on Upper Limb Function in Individuals With Parkinson's DiseaseNov 9, 2026NCT07925567
- Evaluating the Effect of the Zeen Mobility Device on Clinical Practicality, Safety, and Impact (Via Assessments of Walking, Standing Tolerance, Balance, Endurance, Effort, and Participation in Daily Tasks) in an Outpatient Rehabilitation Setting for Individuals With Mobility Impairments.Nov 6, 2026NCT07923201
- Compulsive Eating and Brain's Reward System in Different PathologiesNov 6, 2026NCT07923513
- Clinical Safety and Efficacy of Umbilical Cord Mesenchymal Stromal Cells-derived Exosomes in Patients With Parkinson's DiseaseNov 6, 2026NCT07923838
- Longitudinal Observation of Neurodegeneration in Parkinson's Disease Using Molecular Imaging and Blood BiomarkersNov 5, 2026NCT07919262
- Early COMT Inhibition in PDNov 4, 2026NCT07917546
- Exploratory Clinical Trial of UX-DA003 Injection for the Treatment of Patients With Parkinson's DiseaseNov 3, 2026NCT07911670
- Stanford University Neurofiber StudyNov 3, 2026NCT07914387
- Non-invasive Vagus Nerve Stimulation for Parkinson's DiseaseNov 2, 2026NCT07908498
- Effortful Swallow Exercise With Visual Biofeedback for Tongue Strength in Parkinson's DiseaseOct 30, 2026NCT07906028
- Automated Language Analysis in Neurodegenerative Diseases: Application of Artificial Intelligence ModelsOct 30, 2026NCT07906769
- Strength and Dual-Task on Sarcopenia in People With Parkinson's DiseaseOct 30, 2026NCT07907302
- Cognitive-Motor Training for Gait Adaptability in Parkinson DiseaseOct 30, 2026NCT07907718
- Perception of Action Opportunities for Obstacle Crossing in Parkinson's DiseaseOct 30, 2026NCT07907770
- Lemborexant on Perioperative Sleep Quality in Patients With Parkinson's Disease Undergoing Deep Brain StimulationOct 29, 2026NCT07903038
- Singing Therapy for Rehabilitating Facial Mimicry in Parkinson's Disease: A Randomised Controlled TrialOct 29, 2026NCT07905612
- Twenty-five Years of Advanced RadioTherapy at San Raffaele HospitalOct 26, 2026NCT07894900
- A Phase 1 Study of NCR201 in Parkinson's Disease Patients With Prior DBSOct 26, 2026NCT07896187
- MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT)Oct 23, 2026NCT07892651
- Oculomotor-Pupillary AI Biomarkers in Parkinson'sOct 21, 2026NCT07886450
- Parkinson's Disease in Type 1 Gaucher DiseaseOct 21, 2026NCT07886879
- Multimodal Rehabilitation and Balance Assessment in Parkinson's DiseaseOct 21, 2026NCT07887802
- Ginger-PD: Ginger as a Modifier of Ghrelin Levels and Gut Function in Parkinson's DiseaseOct 20, 2026NCT07882108
- Utilization of Aerobic Exercise to Maintain Neurologic HealthOct 20, 2026NCT07882446
- Motion Capture in Box and Bloks TestOct 20, 2026NCT07883174
- EXercise-induced PhysioLogical Adaptations In Neurological DisordersOct 20, 2026NCT07883720
- MK-0947 PN-002: An Open-label Study to Evaluate Brain α-synuclein Deposition Using Positron Emission Tomography (PET) and [¹⁸F]MK-0947 in Participants With Parkinson's Disease (PD)Oct 19, 2026NCT07880379
- Effect of Artificial Intelligent-based Training and Benson Relaxation Exercises on Caregiver Burden and Stress Levels in Caregivers of Patients With Parkinson's DiseaseOct 15, 2026NCT07876830
Studies
Recruiting first, then most recently updated. Showing 50 of 4,576. Browse all 4,576 → or search them.
- Expiratory Muscle Strength Training for People With Parkinson's DiseaseRecruitingNCT07932561Not applicable1 country
- Effect of Trunk Flexion on Airway Defense in Parkinson's DiseaseRecruitingNCT069553771 country
- Magnetic-Resonance Guided Focused Ultrasound Pallidothalamic Tractotomy for Parkinson's DiseaseNot yet recruitingNCT07925086Not applicable1 country
- Expiratory Muscle Training and Trunk Flexion in Parkinson's DiseaseNot yet recruitingNCT06963918Not applicable1 country
- Virtual Reality for Motor and Cognitive Function in People With Parkinson's DiseaseRecruitingNCT07931040Not applicable1 country
- CnF-DBS for Levodopa-Resistant FOGNot yet recruitingNCT07781696Not applicable1 country
- Remotely Supervised Home-based Transcranial Temporal Interference Stimulation on Motor Symptoms in Parkinson's DiseaseRecruitingNCT07518290Not applicable1 country
- Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS RegistryRecruitingNCT0207113415 countries
- Closed Loop DBS Implanted RC+S StudyEnrolling by invitationNCT03815656Not applicable1 country
- Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle ControlRecruitingNCT07056361Not applicable1 country
- Expiratory Muscle Training in Parkinson's Disease With Forward Trunk FlexionNot yet recruitingNCT07268703Not applicable1 country
- Deep Brain Stimulation (DBS) Retrospective Outcomes StudyRecruitingNCT036646096 countries
- SAD Study in Patients With Parkinson's Disease and Motor FluctuationsRecruitingNCT07422675Phase 13 countries
- Deep Brain Stimulation Surgery for Movement DisordersRecruitingNCT01581580Not applicable1 country
- Deep Brain Stimulation Therapy in Movement DisordersRecruitingNCT02119611Not applicable1 country
- Evaluation and Treatment of Neurosurgical DisordersRecruitingNCT000605411 country
- Study of Gastrointestinal Dysfunction and Enteric Neural Pathology in Patients With Parkinson's DiseaseEnrolling by invitationNCT045663411 country
- Training in Adults With Parkinson's DiseaseNot yet recruitingNCT07928609Not applicable
- A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic TherapyRecruitingNCT07804615Phase 22 countries
- Turkish Validation of the Parkinson Disease Cognitive Functional Rating ScaleEnrolling by invitationNCT072533761 country
- Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson DiseaseRecruitingNCT072278969 countries
- A Phase 1/2a Clinical Study of KL002 in Treatment of Parkinson's DiseaseNot yet recruitingNCT07929480Phase 1/21 country
- Study to Test Effects and Safety of RO7568282 in Early Parkinson's DiseaseRecruitingNCT07781644Phase 23 countries
- Evaluating the Effect of the Zeen Mobility Device on Clinical Practicality, Safety, and Impact (Via Assessments of Walking, Standing Tolerance, Balance, Endurance, Effort, and Participation in Daily Tasks) in an Outpatient Rehabilitation Setting for Individuals With Mobility Impairments.Not yet recruitingNCT07923201Not applicable1 country
- Unilateral and Staged Bilateral Pallidothalamic Tractotomy Using Exablate MRgFUS in Advanced Parkinson's Disease.Not yet recruitingNCT07764874Not applicable1 country
- The Effects of Ischemic Conditioning in Individuals With Parkinson's DiseaseNot yet recruitingNCT06293118Not applicable
- Early Molecular Biomarkers for Differentiating Parkinsonian SyndromesEnrolling by invitationNCT076048831 country
- Compulsive Eating and Brain's Reward System in Different PathologiesNot yet recruitingNCT07923513Not applicable1 country
- Striatal and Extra-Striatal Cholinergic Terminal Density in LRRK2-PD MutationRecruitingNCT076429081 country
- Parkinson's Disease in Type 1 Gaucher DiseaseRecruitingNCT078868791 country
- Neocortical Microarchitecture of Executive FunctionRecruitingNCT06778135Not applicable1 country
- Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease PatientsRecruitingNCT07371338Phase 11 country
- Accelerated rTMS for Apathy in Parkinson's DiseaseRecruitingNCT07399496Not applicable1 country
- Visuospatial and Affective Abilities in Parkinson DiseaseEnrolling by invitationNCT06341829Not applicable1 country
- Longitudinal Observation of Neurodegeneration in Parkinson's Disease Using Molecular Imaging and Blood BiomarkersNot yet recruitingNCT07919262
- A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's DiseaseRecruitingNCT07174310Phase 317 countries
- Comparative Effects of Virtual Reality and Proprioceptive Neuromuscular Facilitation in Patients With Parkinson's DiseaseNot yet recruitingNCT07308093Not applicable1 country
- Tributyrin for Progressive Supranuclear Palsy (PSP): Virtual TrialRecruitingNCT07863180Phase 1/21 country
- Phase I/II Clinical Trial of UX-DA003 Injection for the Treatment of Patients With Parkinson's DiseaseRecruitingNCT07733349Phase 1/21 country
- Effect of Hand Rehabilitation on Cognitive Function in Patients With PDEnrolling by invitationNCT07702929Not applicable1 country
- Evaluation of Impaired Mobility in Chronic Illness Constitution of a CohortRecruitingNCT04375280Not applicable1 country
- Effect of Botulinum Toxin on Resting Tremor of the Refractory Upper Limb in ParkinsoniansNot yet recruitingNCT07822893Phase 31 country
- Treatment of Cognitive and Sensorimotor Deficits in Parkinson's Disease With High Definition Transcranial Direct Current StimulationEnrolling by invitationNCT07534397Not applicable1 country
- Automated Language Analysis in Neurodegenerative Diseases: Application of Artificial Intelligence ModelsRecruitingNCT07906769Not applicable1 country
- Effects of Microelectrode-based Brain Stimulation in HumansRecruitingNCT07820189Not applicable1 country
- A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson's DiseaseRecruitingNCT07157735Phase 21 country
- Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced DevicesRecruitingNCT07066137Not applicable1 country
- Exploratory Clinical Trial of UX-DA003 Injection for the Treatment of Patients With Parkinson's DiseaseRecruitingNCT07911670Early Phase 11 country
- Stanford University Neurofiber StudyNot yet recruitingNCT07914387Phase 11 country
- Non-invasive Vagus Nerve Stimulation for Parkinson's DiseaseNot yet recruitingNCT07908498Not applicable