DrugBiological
Rituximab clinical trials
Also written Rituxan, MabThera, IDEC-C2B8 and IDEC-102.
Includes 3 studies of 131I-rituximab.
- studies test it
- 1,389
- open now
- 177
- in phase 3
- 247
- first study started
- 1993
Keep track of what changes. Save the Rituximab studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
- Rituximab
- 1,114
Development codes
Combined with it in one product
Biosimilars in development
- ABP 798
- 3
- CT-P10
- 3
- SAIT101
- 2
- IBI301
- 2
Studies by the year they started
1,377 studies that test it; most in 2006 (86); 1 more planned to start later
| Year | Studies |
|---|---|
| 1993 | 1 |
| 1995 | 2 |
| 1997 | 6 |
| 1998 | 16 |
| 1999 | 18 |
| 2000 | 19 |
| 2001 | 22 |
| 2002 | 33 |
| 2003 | 53 |
| 2004 | 75 |
| 2005 | 74 |
| 2006 | 86 |
| 2007 | 70 |
| 2008 | 68 |
| 2009 | 71 |
| 2010 | 59 |
| 2011 | 62 |
| 2012 | 63 |
| 2013 | 47 |
| 2014 | 43 |
| 2015 | 52 |
| 2016 | 46 |
| 2017 | 28 |
| 2018 | 39 |
| 2019 | 48 |
| 2020 | 46 |
| 2021 | 36 |
| 2022 | 31 |
| 2023 | 49 |
| 2024 | 36 |
| 2025 | 41 |
| 2026 | 37 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 15
- Phase 1
- 314
- Phase 2
- 876
- Phase 3
- 247
- Phase 4
- 65
- No phase
- 48
What it is tested for
Each study’s main condition, where its own words name it.
- Lymphoma
- 169
Who runs them
Industry 262 · Other 1,127
M.D. Anderson Cancer Center (81) · Hoffmann-La Roche (69) · National Cancer Institute (NCI) (59) · Memorial Sloan Kettering Cancer Center (26) · Mayo Clinic (24) · Genentech, Inc. (24) · Assistance Publique - Hôpitaux de Paris (22) · Alliance for Clinical Trials in Oncology (19)
Often tested with
Tested in the same studies.
Cyclophosphamide (163) · Lenalidomide (99) · Fludarabine (91) · Bendamustine (83) · Vincristine (65) · Prednisone (65) · Bortezomib (63) · Doxorubicin (58)
Studies
Open first, then newest update. How each study uses Rituximab is read from its arms, and is right about nine times in ten.
Testing it · 1,389
- Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular LymphomaRecruitingPhase 3National Cancer Institute (NCI)NCT06337318Written as Rituximab
- A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)RecruitingPhase 3BeOne MedicinesNCT06943872Written as Rituximab
- The HIt HArd and hiT Early in Multiple Sclerosis TrialRecruitingPhase 2Uppsala UniversityNCT07517185Written as Sequential treatment with rituximab and cladribine
- Golcadomide in Combination With Rituximab for the Treatment of Patients With Relapsed or Refractory Mantle Cell LymphomaRecruitingPhase 1/2City of Hope Medical CenterNCT07578077Written as Rituximab
- Pembrolizumab, Ibrutinib and Rituximab in PCNSLRecruitingPhase 1/2Dana-Farber Cancer InstituteNCT04421560Written as Rituximab
- Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin LymphomaRecruitingPhase 2University of WashingtonNCT07097363Written as Rituximab
- Autoantibody Reduction Therapy for Progressive Idiopathic Pulmonary FibrosisNot yet recruitingPhase 2University of Alabama at BirminghamNCT07674745Written as Rituximab
- Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell TherapyRecruitingPhase 2Mayo ClinicNCT06834373Written as Rituximab
- Rituximab for Treatment of Checkpoint Inhibitor Induced Immune-related Adverse EventsRecruitingPhase 1Inge Marie SvaneNCT07694414Written as Rituximab (RTX)
- Loncastuximab Tesirine and Rituximab as Bridging Therapy Before Standard-of-care CAR-T Therapy in Patients With Large B-cell Lymphoma (CORAL)RecruitingPhase 2University of UtahNCT06788964Written as Rituximab
- Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS)RecruitingPhase 2National Cancer Institute (NCI)NCT01419561Written as Rituximab
- Rituximab Plus Cyclosporine in Idiopathic Membranous NephropathyRecruitingPhase 2National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT00977977Written as Rituximab Infusion
- Tafasitamab and Rituximab for the Treatment of Newly Diagnosed Follicular LymphomaRecruitingPhase 2University of WashingtonNCT07731789Written as Rituximab
- Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell LymphomaRecruitingPhase 1/2City of Hope Medical CenterNCT03523975Written as Rituximab
- A Trial to Find Out if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone LymphomaRecruitingPhase 3Regeneron PharmaceuticalsNCT06149286Written as Rituximab
- Acalabrutinib, Lenalidomide, and Rituximab for the Treatment of CD20 Positive Stage III-IV, Grade 1-3a Follicular LymphomaRecruitingPhase 2M.D. Anderson Cancer CenterNCT04404088Written as Rituximab
- Combination of Rituximab and Cyclosporine in the Treatment of Primary Membranous NephropathyRecruitingPhase 2/3Peking University First HospitalNCT07861204Written as rituximab
- A Study of Pirtobrutinib, Venetoclax, and Rituximab in People With Waldenström's Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)RecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT07231952Written as Rituximab
- Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCLRecruitingPhase 2AstraZenecaNCT05952024Written as Rituximab
- Loncastuximab and Roflumilast Added to R-CHOP (Lo-(Rituximab and Roflumilast) RR-CHOP) for Naïve High-Risk Diffuse Large B-cell Lymphoma (DLBCL)RecruitingPhase 1The University of Texas Health Science Center at San AntonioNCT06977711Written as Rituximab
See all 1,389 studies that test Rituximab →
Given in every arm · 453 — Rituximab is usual care beside what is tested
- A Study to Assess BMS-986458 Alone and in Combination With Anti-lymphoma Agents in Relapsed/Refractory Non-Hodgkin LymphomasRecruitingPhase 1/2Bristol-Myers SquibbNCT06090539Written as Rituximab
- Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSLRecruitingPhase 1Dana-Farber Cancer InstituteNCT06475235Written as Rituximab
- Study of NX-5948 in Combination With Other Agents in Adults With B-cell MalignanciesRecruitingPhase 1/2Nurix Therapeutics, Inc.NCT07520006Written as rituximab
- A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)RecruitingPhase 2/3Merck Sharp & Dohme LLCNCT05139017Written as Rituximab
- A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)RecruitingPhase 3Merck Sharp & Dohme LLCNCT06717347Written as Rituximab
- Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic LeukemiaRecruitingPhase 3Alliance for Clinical Trials in OncologyNCT03150693Written as Rituximab
- Epcoritamab in Combination With Dose Adjusted EPOCH-R for High-risk Burkitt Lymphoma (BL), The BEDROCK StudyNot yet recruitingPhase 2AIDS Malignancy ConsortiumNCT07662928Written as Rituximab
- Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for LeukemiasRecruitingPhase 1/2National Cancer Institute (NCI)NCT06364423Written as Rituximab
- Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell LymphomaRecruitingPhase 2National Cancer Institute (NCI)NCT04002947Written as Rituximab
- A Clinical Trial of MK-1045 and Rituximab in People With Follicular Lymphoma (MK-1045-007)RecruitingPhase 2/3Merck Sharp & Dohme LLCNCT07634471Written as Rituximab
- Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic LymphomaRecruitingPhase 2National Cancer Institute (NCI)NCT04840602Written as Rituximab
- Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic LymphomaRecruitingPhase 2City of Hope Medical CenterNCT06918431Written as Rituximab
- Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID TrialRecruitingPhase 3SWOG Cancer Research NetworkNCT07220187Written as Rituximab
- Loncastuximab Tesirine and Rituximab as First-line Therapy in Patients With Post-transplant Lymphoproliferative Disorder (PLUTO)Not yet recruitingPhase 1/2University of UtahNCT07573436Written as Rituximab or rituximab biosimilar
- A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)RecruitingPhase 2Merck Sharp & Dohme LLCNCT06890884Written as Rituximab
- A Study of ARC-02 in B-cell NHLRecruitingPhase 1Taiho Oncology, Inc.NCT07691606Written as Rituximab
- A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic LeukemiaRecruitingPhase 1Hoffmann-La RocheNCT05091424Written as Rituximab
- A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin LymphomaRecruitingPhase 1/2Hoffmann-La RocheNCT05533775Written as Rituximab
- A Study of LY4584180 in Adult Participants With Previously Treated Blood CancersRecruitingPhase 1Eli Lilly and CompanyNCT07226843Written as Rituximab
- A Phase II Study of TT-01488 Tablets in Combination With Anti-CD20 Monoclonal Antibody Therapy in Patients With Mantle Cell LymphomaNot yet recruitingPhase 2TransThera Sciences (Nanjing), Inc.NCT07855016Written as Rituximab
Showing 20 of 453.
As the comparator · 97 — what is tested is compared with Rituximab
- IGNITE: Study of Tirabrutinib vs Rituximab and Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)RecruitingPhase 3Ono Pharmaceutical Co., Ltd.NCT07104032Written as Rituximab
- A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).RecruitingPhase 3Merck Sharp & Dohme LLCNCT05947851Written as Rituximab
- Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM TrialRecruitingPhase 2National Cancer Institute (NCI)NCT05886036Written as Rituximab
- A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell LymphomaRecruitingPhase 3Regeneron PharmaceuticalsNCT06091865Written as Rituximab
- A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell LymphomaRecruitingPhase 3Hoffmann-La RocheNCT06084936Written as Rituximab
- A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular LymphomaRecruitingPhase 3Regeneron PharmaceuticalsNCT06091254Written as Rituximab
- A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) InhibitorsRecruitingPhase 3BeOne MedicinesNCT06846671Written as Rituximab
- Rituximab Versus Ravulizumab, Inebilizumab, Satralizumab, and Eculizumab in NMOSDRecruitingPhase 4Massachusetts General HospitalNCT07010302Written as Rituximab (R)
- A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People With Hairy Cell Leukemia (HCL)RecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT06561360Written as Rituximab
- Evaluation of Iopofosine I 131 vs. R-CD in WM PatientsNot yet recruitingPhase 3Cellectar Biosciences, Inc.NCT07766421Written as Rituximab (active comparator)
- A Study to Evaluate the Safety and Efficacy of SCTB35 in Combination With Lenalidomide in Patients With Relapsed or Refractory Follicular LymphomaRecruitingPhase 3Sinocelltech Ltd.NCT07562022Written as Rituximab
- A Study to Evaluate the Safety and Efficacy of SCTB35 in Combination With Gemcitabine and Oxaliplatin in Patients With Relapsed or Refractory Diffuse Large B-Cell LymphomaRecruitingPhase 3Sinocelltech Ltd.NCT07570823Written as Rituxumab
- A Clinical Trial to Evaluate the Efficacy and Safety of TQB3909 Tablets Versus Investigator's Choice in the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)Not yet recruitingPhase 3Chia Tai Tianqing Pharmaceutical Group Co., Ltd.NCT07753369Written as Rituximab injection
- A Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL.RecruitingPhase 3Ascentage Pharma Group Inc.NCT06319456Written as Rituximab
- HDM2005 Combination Therapy in Relapsed/Refractory Mantle Cell LymphomaNot yet recruitingPhase 1Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.NCT07697339Written as Rituximab plus lenalidomide
- A Study of SNP-ACTH (1-39) Gel in Patients With Primary Membranous NephropathyRecruitingPhase 3Cerium Pharmaceuticals, Inc.NCT05696613Written as Rituximab
- Mosunetuzumab-Lenalidomide Versus Investigator Choices in Patients With Relapsed or Refractory Marginal Zone LymphomaRecruitingPhase 3The Lymphoma Academic Research OrganisationNCT06006117Written as Rituximab (R)
- A Study of DZD8586 Versus Investigator's Choice in r/r CLL/SLL (TAI-SHAN6)RecruitingPhase 3Dizal PharmaceuticalsNCT07139873Written as Rituximab
- Relapsed Follicular Lymphoma Randomised Trial Against Standard ChemoTherapyRecruitingPhase 2University of BirminghamNCT05848765Written as Rituximab
- Early Stage Follicular LymphOma and RadioTherapy PLUS Anti-CD20 AntibodyRecruitingPhase 3Heidelberg UniversityNCT05045664Written as Standard
Showing 20 of 97.
Codes
What other systems call Rituximab · ClinicalTrials.gg INT006567
- MeSH (NLM) D000069283RituximabConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 4F4X42SYQ6RITUXIMABConfirmed FDA, NLM, Wikidata
- RxNorm 121191Confirmed FDA, Wikidata
- Wikidata Q412323rituximabConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C1702RituximabOne source FDA
- DrugBank DB00073One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000069283 | Rituximab | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 4F4X42SYQ6 | RITUXIMAB | Confirmed FDA, NLM, Wikidata |
| RxNorm | 121191 | — | Confirmed FDA, Wikidata |
| Wikidata | Q412323 | rituximab | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C1702 | Rituximab | One source FDA |
| DrugBank | DB00073 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.