Neuromuscular Diseases clinical trials
The registry lists 361 studies for Neuromuscular Diseases across more than 10 countries. 97 are recruiting or about to start. 131 of them are mainly about Neuromuscular Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 96 narrower conditions too, such as Fibromyalgia: 14,830 studies, 3,487 open.
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Status
Who runs them
Centre d'Investigation Clinique et Technologique 805 (23) · National Institute of Neurological Disorders and Stroke (NINDS) (10) · Assistance Publique - Hôpitaux de Paris (10) · Columbia University (9) · Institut de Myologie, France (8) · Guy's and St Thomas' NHS Foundation Trust (7) · MarsiBionics (6) · ResMed (5)
What is being tested here
Drugs under test in Neuromuscular Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab · Phase 3 · Scholar Rock, Inc.
- Jul 2027A Phase 3 Study of NTLA-2001 in ATTRv-PN · Phase 3 · Intellia Therapeutics
- Nov 2026Genesis Electrical Impedance Tomography (EIT): A Preliminary Study · University of Colorado, Denver
- Nov 2026Usability of the FTEXES Wearable Textile Platform for Functional Electrical Stimulation and EMG · Politecnico di Milano
- Nov 2026Does Chronic Pain Change Over Time in Children With Duchenne Muscular Dystrophy? · Antalya Training and Research Hospital
- Dec 2026Nebulised Hypertonic Saline to Decrease Respiratory Exacerbations in Neuromuscular Disease or Neurodisability · Imperial College London
- Dec 2026VirtualPark_Pediatric · Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato
- Dec 2026The Importance of Positive Expiratory Pressure Associated With the In-exsufflator in ALS Patients · Groupe Hospitalier du Havre
- Dec 2026Pelvic Floor Muscle Training for Women with Myotonic Dystrophy · Université de Sherbrooke
- Dec 2026Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting · ABLE Human Motion S.L.
Who these studies take
Of the 70 Neuromuscular Diseases studies recruiting now, 39 (56%) set no upper age limit and 23 (33%) stop at 75 or younger. 36 (51%) take children under 18. 1 (1%) are for women only and 3 (4%) for men only; 16 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 28 (40%) | 31 (44%) |
| 18 | 58 (83%) | 59 (84%) |
| 30 | 57 (81%) | 56 (80%) |
| 40 | 57 (81%) | 56 (80%) |
| 50 | 56 (80%) | 55 (79%) |
| 65 | 54 (77%) | 53 (76%) |
| 75 | 49 (70%) | 48 (69%) |
| 85 | 46 (66%) | 45 (64%) |
Across all 361 studies, recruiting or not: 41% stop at 75 or younger and 34% at 65; 47% take children; 1% are for women only and 8% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Neuromuscular Diseases studies take
Of 84 interventional studies with no phase under Neuromuscular Diseases, half reached primary completion within 25 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 25 mo12–43 · 84 studies | — | 31 mo18–47 · 75 studies |
| Observational | 37 mo12–114 · 70 studies | — | 38 mo12–114 · 64 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered4
- Usability of the FTEXES Wearable Textile Platform for Functional Electrical Stimulation and EMGNov 6, 2026NCT07922980
- Incidence and Risk Factors of Pneumothorax in Patients With Neuromuscular DiseasesNov 2, 2026NCT07909018
- Register for Medical Data, Functional Scales, and Care Outcomes in ALS, SMA, and Other Motor System DisordersOct 28, 2026NCT07900672
- Does Chronic Pain Change Over Time in Children With Duchenne Muscular Dystrophy?Oct 23, 2026NCT07892196
Studies
Recruiting first, then most recently updated. Showing 50 of 361. Browse all 361 → or search them.
- A Phase 3 Study to Evaluate the Safety and Efficacy of AOC 1044 (Also Referred to as Delpacibart Zotadirsen) in Participants With DMD With Gene Mutations Amenable to Exon 44 SkippingRecruitingNCT07587242Phase 310 countries
- A Real-World Medical Chart Review of Spinal Muscular Atrophy Patients Treated With Onasemnogene Abeparvovec in Saudi ArabiaNot yet recruitingNCT07737756
- Usability of the FTEXES Wearable Textile Platform for Functional Electrical Stimulation and EMGNot yet recruitingNCT07922980Not applicable1 country
- Register for Medical Data, Functional Scales, and Care Outcomes in ALS, SMA, and Other Motor System DisordersRecruitingNCT079006721 country
- Does Chronic Pain Change Over Time in Children With Duchenne Muscular Dystrophy?RecruitingNCT078921961 country
- A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.RecruitingNCT06916806Phase 110 countries
- Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy VolunteersRecruitingNCT01900132Not applicable1 country
- Establishing Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1) ExtensionRecruitingNCT077002251 country
- A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type IEnrolling by invitationNCT06926621Phase 28 countries
- Characterizing Perceived Physical Fatigability in Nusinersen-treated SMARecruitingNCT069558971 country
- Non-Invasive Respiratory MonitorRecruitingNCT02851043Not applicable1 country
- A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene) in Adult Participants With Late-Onset Pompe Disease (PROGRESS-GT LOPD)RecruitingNCT07282847Phase 1/21 country
- A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ATI-105 in Healthy AdultsNot yet recruitingNCT07869654Phase 11 country
- Registry for Duchenne and Becker Muscular DystrophyRecruitingNCT074021222 countries
- Managed Access Program for Del-zota in Participants With DMD Mutations Amenable to Exon 44 SkippingAvailableNCT072507371 country
- Virtual Walking Therapy for Neuropathic Pain Following Incomplete Spinal Cord InjuryRecruitingNCT06330181Not applicable1 country
- The Precision Mito- Mito Map COMPASS StudyNot yet recruitingNCT078561211 country
- Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked PainNot yet recruitingNCT07101978Not applicable1 country
- 3D Hand Orthosis TrialRecruitingNCT07633821Not applicable1 country
- Data Collection of Standard Care of Patients in the EMG SectionRecruitingNCT050413871 country
- Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical SettingRecruitingNCT07745712Not applicable1 country
- Biofluid Research on Age-Related or Inherited NeurodegenerationRecruitingNCT077987001 country
- UK SMA Patient RegistryRecruitingNCT042925741 country
- VirtualPark_PediatricRecruitingNCT07580365Not applicable1 country
- Gamification Effects on the 6-Minute Walk Test in ChildrenRecruitingNCT07216339Not applicable1 country
- Analysis of Human ALS Tissues and Registry of ALS PatientsRecruitingNCT050671791 country
- CIMR Neuromuscular Research BiobankRecruitingNCT054345721 country
- A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)RecruitingNCT07071935Phase 21 country
- Personalized Training for People With Rare Neuromuscular DisordersRecruitingNCT06708468Not applicable1 country
- Assessment of Volume-targeted Ventilation in Patients With Neuromuscular DiseaseRecruitingNCT06339580Phase 21 country
- Optimisation of Mechanical Insufflation:ExsufflationRecruitingNCT04163198Not applicable1 country
- Investigating Health Related Quality of Life in Patients With Chronic Respiratory FailureRecruitingNCT042367261 country
- Does the Coaching Function Improve the Learning of Mechanical In-exsufflation (MI-E) in Paediatric Subjects?RecruitingNCT06190431Not applicable1 country
- Efficacy, Safety, and Tolerability of Zeleciment Rostudirsen (DYNE-251) Administered Intravenously Every 4 Weeks in Ambulatory Participants With Duchenne Muscular Dystrophy (FORZETTO)RecruitingNCT07608432Phase 31 country
- Northwestern Neuromuscular Disease BiorepositoryRecruitingNCT074775091 country
- Physical Activity Level at Home in CMT1A Patients: Wearable Sensor AssessmentNot yet recruitingNCT075917791 country
- Usability and User Experience of a Virtual Reality Rehabilitation Game Platform in Individuals With Duchenne Muscular DystrophyEnrolling by invitationNCT075652721 country
- Invasive Home Ventilation in DenmarkRecruitingNCT074671871 country
- Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)RecruitingNCT07357428Not applicable1 country
- Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular DisordersRecruitingNCT068394691 country
- Respiratory Muscles and Work of Breathing in ChildrenRecruitingNCT05051254Not applicable1 country
- An Open-Label Extension Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1 (FREEDOM-OLE)RecruitingNCT07220603Phase 21 country
- Wearable Sensors to Detect Atypical Muscle Activation in Young InfantsRecruitingNCT069705221 country
- Spastic Paraplegia - Centers of Excellence Research NetworkRecruitingNCT065539761 country
- Walking Function Outcomes Following Surgical Correction With Rehabilitation Versus Physical Therapy Alone in Charcot-Marie-Tooth Disease: A Bidirectional Cohort StudyNot yet recruitingNCT07432035
- Evaluation of the Role of miR-1 in the Pathogenesis and as a Biomarker in Muscular Dystrophies and Congenital MyopathiesRecruitingNCT07415837Not applicable1 country
- Impact Study on Users of Upper Limb Assistive DevicesRecruitingNCT074291881 country
- Measuring Physical Activity With ActivPalRecruitingNCT060840261 country
- The Importance of Positive Expiratory Pressure Associated With the In-exsufflator in ALS PatientsRecruitingNCT06249412Not applicable1 country
- EMMVIES : Walking Training at Home in VIrtual Reality for Children With Chronic Illnesses Impacting Physical HealthRecruitingNCT07021638Not applicable1 country