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Multiple Sclerosis clinical trials

The registry lists 3,264 studies for Multiple Sclerosis across more than 10 countries. 659 are recruiting or about to start. 2,606 of them are mainly about Multiple Sclerosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 2 narrower conditions too, such as Multiple Sclerosis, Relapsing-Remitting: 3,668 studies, 705 open.

ClinicalTrials.gov finds 3,957 studies for Multiple Sclerosis. How that becomes 3,261 here

This page counts the studies the registry files under Multiple Sclerosis, and those it files under no condition that list Multiple Sclerosisthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 3,957Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −403Filed under a narrower condition, counted on its own pageMultiple Sclerosis, Relapsing-Remitting 311 · Multiple Sclerosis, Chronic Progressive 90
  3. −17List Multiple Sclerosis as a condition, but the registry did not file them under itMost often written as “Relapsing Multiple Sclerosis” (5), “Multiple Sclerosis Transplant” (1), and “Multiple Sclerosis Stem Cell Transplant” (1). The registry filed them under other conditions only, most often Recurrence (3) and Motor Activity (3).
  4. −276Match it another way47 name it in the title, 1 in a keyword, and 228 by a synonym or other text the search reads.
  5. 3,261The count on this page104 of them list Multiple Sclerosis in their own words; the registry filed them under no condition.

Get an email when these change. Save the Multiple Sclerosis studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

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Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

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Status

Completed
1,815
Recruiting
430
Status unknown
324
Terminated
200
Not yet recruiting
178
Active, not recruiting
169

Phase

Phase 2
402
Phase 3
272
Phase 1
254
Phase 4
180
Early Phase 1
30

Where

United States
1,192
France
376
Turkey
307
Italy
289
Canada
257
United Kingdom
252

Who runs them

Biogen (127) · Novartis Pharmaceuticals (91) · Merck KGaA, Darmstadt, Germany (39) · Bayer (37) · Sanofi (35) · Hasselt University (34) · Kessler Foundation (31) · National Institute of Neurological Disorders and Stroke (NINDS) (30)

What is being tested here

Drugs under test in Multiple Sclerosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Ocrelizumab31023
Ublituximab304
Cladribine2414
Metformin206
Clemastine214
Cannabidiol203
Autologous Bispecific BCMA/CD19-targeted CAR-T Cells GC012F203
Remibrutinib212
4-Aminopyridine11127
Natalizumab1620

Drug classes tested here Tyrosine kinase inhibitors (TKIs) 4 open · Antihistamines 4 open · Antimetabolites 3 open · Serotonin receptor agonists 2 open · Potassium channel blockers 1 open

Coming up

43phase 3 studies under way
222studies finish main data collection within a year10 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 430 Multiple Sclerosis studies recruiting now, 163 (38%) set no upper age limit and 211 (49%) stop at 75 or younger. 40 (9%) take children under 18. 20 (5%) are for women only and 1 (<1%) for men only; 96 (22%) take healthy volunteers.

Recruiting studies that take each age, of 430
AgeWomenMen
1032 (7%)29 (7%)
18384 (89%)370 (86%)
30407 (95%)388 (90%)
40410 (95%)392 (91%)
50406 (94%)388 (90%)
65353 (82%)343 (80%)
75247 (57%)239 (56%)
85200 (47%)192 (45%)

Across all 3,264 studies, recruiting or not: 59% stop at 75 or younger and 48% at 65; 8% take children; 3% are for women only and 1% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Multiple Sclerosis studies take

Of 96 phase 3 interventional studies under Multiple Sclerosis, half reached primary completion within 42 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 130 mo9–56 · 91 studies13 mo6–32 · 38 studies50 mo19–71 · 53 studies
Phase 1/247 mo31–89 · 33 studies——
Phase 236 mo19–64 · 92 studies25 mo16–47 · 43 studies42 mo31–68 · 49 studies
Phase 342 mo26–63 · 96 studies39 mo26–54 · 71 studies—
Phase 434 mo23–59 · 69 studies29 mo19–37 · 36 studies—
Interventional, no phase21 mo9–43 · 869 studies—22 mo8–43 · 847 studies
Observational41 mo15–75 · 425 studies49 mo27–81 · 91 studies36 mo13–73 · 334 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting8

Show 3 more

Results posted1

Stopped2

Newly registered19

Show 14 more

Studies

Recruiting first, then most recently updated. Showing 50 of 3,264. Browse all 3,264 → or search them.