Multiple Sclerosis clinical trials
The registry lists 3,447 studies for Multiple Sclerosis across more than 10 countries. 658 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Completed
- 1,940
- Recruiting
- 426
- Status unknown
- 343
- Terminated
- 240
- Not yet recruiting
- 179
- Active, not recruiting
- 161
Phase
- Phase 2
- 463
- Phase 3
- 306
- Phase 1
- 285
- Phase 4
- 216
- Early Phase 1
- 32
Where
- United States
- 1,253
- France
- 392
- Italy
- 314
- Germany
- 297
- Canada
- 281
- United Kingdom
- 280
Who runs them
Biogen (163) · Novartis Pharmaceuticals (90) · Merck KGaA, Darmstadt, Germany (52) · Bayer (46) · Kessler Foundation (32) · Hasselt University (32) · Sanofi (31) · National Institute of Neurological Disorders and Stroke (NINDS) (30)
Studies
Recruiting first, then most recently updated. Showing 50 of 3,447 — search for more.
- The Effects of High-Intensity Interval Training on Gait, Balance, and Cognitive Functions in Individuals With Multiple SclerosisNot yet recruitingNCT07578740Not applicable1 country
- A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)RecruitingNCT064337523 countries
- Use of a Portable Pupillometer to Detect Optic Nerve Impairment in Patients With Suspected Multiple SclerosisNot yet recruitingNCT07837050Not applicable
- TWEAK, a New Biomarker for Predicting Inflammatory Relapses in Multiple SclerosisRecruitingNCT03974997Not applicable1 country
- Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVORecruitingNCT03816345Phase 12 countries
- Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous SystemRecruitingNCT007943521 country
- Exploring Reproductive Decision-Making Among Women With Multiple SclerosisNot yet recruitingNCT07829822
- A Study Evaluating the Effect of BRIUMVI® (Ublituximab) on Pregnancy and Infant Outcomes in Participants With Multiple Sclerosis (MS)RecruitingNCT064337651 country
- Treatment of Participants With Primary or Secondary Progressive Multiple SclerosisRecruitingNCT07477639Phase 1/21 country
- A Study to Evaluate Pharmacokinetics (PK) and Safety of Subcutaneous (SC) Ublituximab Administered at Various Injection Sites and Relative Bioavailability Via Autoinjector (AI) Versus Syringe Subcutaneously in Participants With Multiple Sclerosis (MS)RecruitingNCT07503873Phase 26 countries
- Motor Imagery and Action Observation for Gait Function in MSRecruitingNCT07137624Not applicable1 country
- A Study to Evaluate the Preliminary Efficacy and Safety of Terfenadine in Patients With Relapsing-Remitting Multiple SclerosisRecruitingNCT07827716Phase 21 country
- Aerobic Fitness in Multiple Sclerosis: The Relationship Between Balance and Sensory Dual-TaskingNot yet recruitingNCT07815990
- Delivery of a Culturally Tailored Exercise Training Intervention for Hispanics With Multiple SclerosisRecruitingNCT07606742Not applicable1 country
- Prevalence of Primary Headache in Multiple Sclerosis PatientsNot yet recruitingNCT07826221
- Body Awareness, Trunk Stability, and Arm Function in MSRecruitingNCT071515341 country
- A Phase 1/2a Study of Oral PRO-1562 in Healthy Subjects and Patients With Relapsing Multiple SclerosisNot yet recruitingNCT07826689Phase 1/21 country
- Monitoring Intensity During Balance Training in Persons With Multiple SclerosisRecruitingNCT07805850Not applicable1 country
- A Study of C-CAR168 in Participants With Progressive Multiple SclerosisNot yet recruitingNCT07825389Phase 1/2
- A Study of Imaging in Demyelinating DiseasesEnrolling by invitationNCT05805839Phase 21 country
- Clinical Applications of Advanced Ophthalmic ImagingRecruitingNCT03135327Not applicable1 country
- Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS)RecruitingNCT000012481 country
- Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis PlaquesRecruitingNCT02784210Phase 21 country
- FES: Effect on Walking in the Real World and Participation in Daily Life in People With Multiple Sclerosis.Enrolling by invitationNCT07706114Not applicable1 country
- Cannabis (THC vs. CBD) in Multiple SclerosisRecruitingNCT06261489Phase 21 country
- Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current StimulationRecruitingNCT05958381Not applicable1 country
- A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS)RecruitingNCT067801502 countries
- RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical IllnessesRecruitingNCT07002034Phase 21 country
- Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple SclerosisRecruitingNCT07325292Phase 35 countries
- A Clinical Study to Evaluate the Safety and Efficacy of GT802 Injection in the Treatment of Relapsing/Refractory Multiple SclerosisNot yet recruitingNCT07748637Early Phase 11 country
- The EXOPULSE Study - a Database for Routine Follow-up of Clinical OutcomesRecruitingNCT059012591 country
- Comparative Study of Two Vaccination Schedules for the Subunit Herpes Zoster Vaccine in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disease Patients Treated With Anti-CD20 Therapy: an Open-label Randomised Controlled TrialNot yet recruitingNCT07818356Phase 41 country
- Digital App for Speech & Health MonitoringRecruitingNCT064504181 country
- Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple SclerosisRecruitingNCT06408259Phase 311 countries
- High-Intensity Interval Training for Walking and Function Across Different Multiple Sclerosis Disability LevelsRecruitingNCT07771868Not applicable1 country
- Emerging Indications for Hyperbaric Oxygen TreatmentNot yet recruitingNCT07240649Phase 4
- A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune DisordersRecruitingNCT06680037Phase 11 country
- Driving Performance in Parkinson's Disease and Multiple Sclerosis Using a Driving SimulatorNot yet recruitingNCT07809828
- A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis SpasticityRecruitingNCT06782490Phase 27 countries
- Exploring the Utility of [18F]3F4AP for Demyelination ImagingRecruitingNCT06999434Phase 11 country
- Early Detection of Selected Neuropathologies in Motor Vehicle DriversRecruitingNCT073608861 country
- A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple Sclerosis Who Switch From an Approved Anti-CD20 TherapyRecruitingNCT07609719Phase 42 countries
- Confirmatory Trial for Alleviating Fatigue in Multiple SclerosisEnrolling by invitationNCT06441617Not applicable1 country
- Early Symptoms in Multiple Sclerosis: an Investigation Using fMRI and Gait Analysis to Develop Personalized Balance Training for People With Low DisabilityNot yet recruitingNCT07805733Not applicable
- Short Sprint Interval Training in People With Multiple SclerosisRecruitingNCT07804264Not applicable1 country
- [18F]F-DED PET Imaging of Reactive Astrocytes in Multiple SclerosisNot yet recruitingNCT07805473Not applicable1 country
- MS-Related Disability Worsening and Thalamic Volume LossEnrolling by invitationNCT077539281 country
- Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)RecruitingNCT017301311 country
- Evaluation of the Safety and Efficacy of a Full-Body Electrostimulation Garment for Individuals With Neurological and Neuromuscular Conditions That Cause Spasticity, Hyperreflexia, and PainRecruitingNCT07132775Not applicable1 country
- Identifying and Characterizing Preclinical MSRecruitingNCT057877951 country