Schizophrenia clinical trials
The registry lists 3,464 studies for Schizophrenia across more than 10 countries. 467 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 2,277
- Status unknown
- 341
- Recruiting
- 320
- Terminated
- 245
- Not yet recruiting
- 128
- Withdrawn
- 74
Phase
- Phase 3
- 464
- Phase 2
- 463
- Phase 4
- 439
- Phase 1
- 362
- Early Phase 1
- 25
Where
- United States
- 1,420
- China
- 241
- France
- 236
- Canada
- 175
- Taiwan
- 175
- Germany
- 174
Who runs them
Otsuka Pharmaceutical Development & Commercialization, Inc. (88) · AstraZeneca (76) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (73) · University of Maryland, Baltimore (64) · Shanghai Mental Health Center (62) · Yale University (53) · Centre for Addiction and Mental Health (51) · VA Office of Research and Development (47)
Studies
Recruiting first, then most recently updated. Showing 50 of 3,464 — search for more.
- Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum DisorderRecruitingNCT06229210Phase 33 countries
- NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With SchizophreniaRecruitingNCT07105098Phase 35 countries
- Efficacy of NBI-1117568 in Preventing Relapse in Adults With SchizophreniaRecruitingNCT07227818Phase 33 countries
- NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With SchizophreniaRecruitingNCT07114874Phase 35 countries
- Frontal Gamma Coherence Neurofeedback for Patients With SchizophreniaNot yet recruitingNCT07659938Not applicable1 country
- Study to Evaluate the Safety and Efficacy of Ublituximab in Participants With SchizophreniaRecruitingNCT07680946Phase 21 country
- Psychological Resilience and Quality of Life Among Caregivers of Patients With SchizophreniaNot yet recruitingNCT07837479
- Early Identification of Patients Presenting a First Psychotic Episode, Non Answering to First Line Support StrategiesRecruitingNCT026704471 country
- FEEL-GOOD: A Multicenter Trial of a Mindfulness-Based Group Therapy in Young Adults With Early PsychosisRecruitingNCT07645443Not applicable1 country
- A Study of Brenipatide in Adult Participants With SchizophreniaRecruitingNCT07410507Phase 27 countries
- A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and AdolescentsRecruitingNCT07424404Phase 310 countries
- State Representation in Early Psychosis 2RecruitingNCT078342031 country
- Berberine in Treating Negative Symptoms of Schizophrenia: Clinical Efficacy and MechanismsEnrolling by invitationNCT07356765Not applicable1 country
- Voice-Based Biomarkers: A Novel Approach to Monitoring and Predicting Schizophrenia RelapsesRecruitingNCT06613334Not applicable1 country
- Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to TreatmentRecruitingNCT07741981Not applicable1 country
- Intermittent Theta-Burst Stimulation to Improve Negative Symptoms and Cognition in SchizophreniaRecruitingNCT06740747Not applicable1 country
- A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) InhibitorRecruitingNCT07105111Phase 41 country
- Prucalopride for Cognitive Functioning in SchizophreniaNot yet recruitingNCT06474286Not applicable1 country
- A Study of LTX-001 In Adult Participants With Acute Exacerbation of SchizophreniaRecruitingNCT07734493Phase 11 country
- tACS for Self-Other Boundary in SchizophreniaRecruitingNCT07818668Not applicable1 country
- Feasibility and Acceptability of Mobile Mental Health App for SZ and SZANot yet recruitingNCT06474325Not applicable1 country
- Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)RecruitingNCT05276050Not applicable1 country
- Evaluate Pharmacokinetics, Safety, and Tolerability of AX251 LAI in Patients With SchizophreniaRecruitingNCT07484204Phase 11 country
- DecNef for AVH in SchizophreniaNot yet recruitingNCT07779226Phase 1/21 country
- Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis UseRecruitingNCT05445180Not applicable1 country
- Building a Computational Model of Auditory HallucinationsNot yet recruitingNCT07820553
- A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With SchizophreniaRecruitingNCT07145918Phase 21 country
- Relapse Prevention Trial Evaluating KarXT Treatment in SchizophreniaRecruitingNCT07686263Phase 39 countries
- Effectiveness of a Board Game Intervention on Cognitive and Functional Outcomes in Older Adults With SchizophreniaNot yet recruitingNCT07781007Not applicable1 country
- Phase I Trial of HHK101 in Patients With SchizophreniaNot yet recruitingNCT07815210Phase 1
- Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant SchizophreniaRecruitingNCT07184619Phase 34 countries
- Multi-target TMS for Schizophrenia Negative SymptomsNot yet recruitingNCT07559084Not applicable1 country
- 52-week Open Label Safety-Tolerability StudyRecruitingNCT07369154Phase 31 country
- Efficacy and Safety of Individualized Sequential Accelerated Theta Burst Stimulation in Improving Cognitive Function in SchizophreniaNot yet recruitingNCT07806877Not applicable
- Do Antipsychotic Agents Induce Supersensitivity in Humans: A Combined PET/MRI Study in Patients With SchizophreniaRecruitingNCT03911726Not applicable1 country
- A Relation Between Craving Induction and Treatment Response in Deep Transcranial Magnetic Stimulation (dTMS) for Reducing Antipsychotic-induced Weight Gain in SchizophreniaNot yet recruitingNCT07805980Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)RecruitingNCT07288567Phase 34 countries
- The Safety and Effectiveness of dTMS for Reducing Antipsychotic-induced Weight GainNot yet recruitingNCT07795554Not applicable1 country
- A Prospective, Observational, Single-Arm, Multicenter Real-World Study Evaluating the Treatment Pattern, Safety and Effectiveness of Xanomeline and Trospium Chloride Capsules (KarXT) in the Treatment of Chinese Adult Participants With SchizophreniaNot yet recruitingNCT07802132
- Genetic Basis of the Risk and Consequences of Cannabis Exposure in HumansRecruitingNCT06058702Phase 11 country
- Follow-up of Adolescents With Autism and Psychotic Symptoms - Psychiatric Co-morbidity and Functional Impairment.RecruitingNCT074278101 country
- A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXTRecruitingNCT07061288Phase 11 country
- A Long-Term Open-Label Study of ML-007C-MA in Adults With SchizophreniaRecruitingNCT07459647Phase 21 country
- Activities to Change Your Mood: A Test of the Acceptability and Initial Efficacy in Clinical Samples and Healthy ControlsRecruitingNCT06911723Not applicable1 country
- Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy ControlsRecruitingNCT07680114Not applicable1 country
- Investigation of Using Non-Wearable Devices to Assess Sleep- Disordered Breathing in Hospitalized Patients With SchizophreniaRecruitingNCT071920421 country
- A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With SchizophreniaRecruitingNCT07615426Phase 11 country
- NEURO-COGS: Neurometabolic Mechanisms of Cognitive Training in SchizophreniaNot yet recruitingNCT07788755Not applicable1 country
- Switching From Twice-Daily to Once-Daily Clozapine Dosing in SchizophreniaRecruitingNCT02639702Phase 41 country
- Improving Quality of Informal Care for People With SchizophreniaNot yet recruitingNCT07781748Not applicable1 country