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Schizophrenia clinical trials

The registry lists 3,563 studies for Schizophrenia across more than 10 countries. 491 are recruiting or about to start. 3,018 of them are mainly about Schizophrenia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Schizophrenia, Treatment-Resistant too: 3,589 studies, 501 open.

ClinicalTrials.gov finds 4,266 studies for Schizophrenia. How that becomes 3,561 here

This page counts the studies the registry files under Schizophrenia, and those it files under no condition that list Schizophreniathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 4,266Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −26Filed under a narrower condition, counted on its own pageSchizophrenia, Treatment-Resistant 24
  3. −87List Schizophrenia as a condition, but the registry did not file them under itMost often written as “Schizophrenia Spectrum and Other Psychotic Disorders” (21), “Schizophrenia and Disorders With Psychotic Features” (11), and “Prodromal Schizophrenia” (11). The registry filed them under other conditions only, most often Schizophrenia Spectrum and Other Psychotic Disorders (33) and Psychotic Disorders (31).
  4. −592Match it another way99 name it in the title, 14 in a keyword, and 479 by a synonym or other text the search reads.
  5. 3,561The count on this page81 of them list Schizophrenia in their own words; the registry filed them under no condition.

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Status

Completed
2,347
Status unknown
343
Recruiting
331
Terminated
244
Not yet recruiting
138
Withdrawn
78

Phase

Phase 3
474
Phase 2
461
Phase 4
452
Phase 1
376
Early Phase 1
28

Where

United States
1,465
China
247
France
240
Canada
193
Taiwan
180
Germany
179

Who runs them

Otsuka Pharmaceutical Development & Commercialization, Inc. (90) · AstraZeneca (79) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (73) · University of Maryland, Baltimore (63) · Shanghai Mental Health Center (60) · Yale University (57) · Centre for Addiction and Mental Health (57) · VA Office of Research and Development (51)

What is being tested here

Drugs under test in Schizophrenia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Xanomeline81419
Trospium8611
Paliperidone642114
Clozapine6637
Cariprazine41422
Direclidine445
Risperidone332125
Aripiprazole337124
Lumateperone3512
HS-10380325

Drug classes tested here Antipsychotics 22 open · Antimuscarinics 8 open · GLP-1 receptor agonists 3 open · Stimulants 1 open · Opioid antagonists 1 open

Coming up

36phase 3 studies under way
165studies finish main data collection within a year12 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 331 Schizophrenia studies recruiting now, 63 (19%) set no upper age limit and 257 (78%) stop at 75 or younger. 42 (13%) take children under 18. 2 (1%) are for women only and 1 (<1%) for men only; 83 (25%) take healthy volunteers.

Recruiting studies that take each age, of 331
AgeWomenMen
1011 (3%)11 (3%)
18299 (90%)298 (90%)
30314 (95%)313 (95%)
40294 (89%)293 (89%)
50271 (82%)271 (82%)
65184 (56%)183 (55%)
7579 (24%)79 (24%)
8570 (21%)70 (21%)

Across all 3,563 studies, recruiting or not: 80% stop at 75 or younger and 74% at 65; 10% take children; 1% are for women only and 3% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Schizophrenia studies take

Of 133 phase 1 interventional studies under Schizophrenia, half reached primary completion within 12 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 112 mo5–19 · 133 studies9 mo5–16 · 108 studies—
Phase 1/254 mo22–70 · 18 studies——
Phase 225 mo15–42 · 101 studies20 mo12–32 · 57 studies43 mo25–73 · 44 studies
Phase 332 mo20–46 · 113 studies32 mo20–41 · 99 studies—
Phase 439 mo20–63 · 88 studies—48 mo27–64 · 71 studies
Interventional, no phase32 mo16–56 · 766 studies—33 mo17–56 · 753 studies
Observational47 mo27–102 · 136 studies—53 mo26–114 · 114 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting6

Show 1 more

Results posted2

Stopped3

Newly registered16

Show 11 more

Studies

Recruiting first, then most recently updated. Showing 50 of 3,563. Browse all 3,563 → or search them.