Cognitive Dysfunction clinical trials
The registry lists 3,835 studies for Cognitive Dysfunction across more than 10 countries. 1,095 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 1,799
- Recruiting
- 745
- Status unknown
- 457
- Not yet recruiting
- 271
- Active, not recruiting
- 227
- Terminated
- 163
Phase
- Phase 2
- 387
- Phase 1
- 165
- Phase 4
- 154
- Phase 3
- 127
- Early Phase 1
- 38
Where
- United States
- 1,344
- China
- 343
- Canada
- 218
- France
- 183
- Italy
- 174
- Spain
- 160
Who runs them
Johns Hopkins University (35) · Chang Gung Memorial Hospital (33) · Massachusetts General Hospital (33) · VA Office of Research and Development (32) · University of California, San Francisco (30) · Wake Forest University Health Sciences (28) · The University of Hong Kong (25) · Icahn School of Medicine at Mount Sinai (24)
Studies
Recruiting first, then most recently updated. Showing 50 of 3,835 — search for more.
- Prediction and Prevention of Postoperative Mortality and MorbidityNot yet recruitingNCT06042413Not applicable1 country
- Memory Support System Feasibility StudyRecruitingNCT05999929Not applicable1 country
- Thrive at Home: A Virtual Reality Social Intervention for Older AdultsNot yet recruitingNCT07835568Not applicable
- Single-center Prospective Longitudinal Study of Taste in Patients With Cognitive Disorders at Different Stages of Severity (Isolated Cognitive Complaint, Minor or Major Neurocognitive Alzheimer-type Disorders) by Analysis of Gustatory Evoked PotentialsRecruitingNCT05888961Not applicable1 country
- Jigsawdio Multisensory Platform for People With Mild Cognitive Impairment, Alzheimer's Disease, or Related DementiasNot yet recruitingNCT07839286Not applicable1 country
- A Novel Multi-Modal Approach to Promote Functional Outcomes in Cognitively Frail Older AdultsRecruitingNCT07497334Not applicable1 country
- Cognitive Impairment in Older Adults With Hematologic MalignanciesNot yet recruitingNCT07842679
- A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)RecruitingNCT07633470Phase 41 country
- PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)RecruitingNCT07169630Phase 11 country
- Evaluation of Blood-Based Biomarkers and Remote Cognitive Assessment for Dementia Triage (SANDBOX)RecruitingNCT078420291 country
- Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)RecruitingNCT06452147Not applicable1 country
- 2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's PatientsNot yet recruitingNCT06432166Phase 1/21 country
- Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain TumourRecruitingNCT05230758Phase 32 countries
- Cognitive Assessment And Post-Operative Complications After Surgery: Linking Anaesthesia And RiskNot yet recruitingNCT074702161 country
- Benefits of Nicotinamide Riboside Upon Cognition and SleepRecruitingNCT05500170Not applicable1 country
- A Study of Retinal Imaging to Detect Abnormal Protein Deposits Associated With Alzheimer's DiseaseRecruitingNCT072542341 country
- A Study of LY3439539 in Participants With Alzheimer's DiseaseRecruitingNCT07598370Phase 14 countries
- Virtual Outreach and Individualized Coaching ExtensionNot yet recruitingNCT07836114Not applicable1 country
- Combating Alzheimer's Through Sleep and ExerciseRecruitingNCT04855630Not applicable1 country
- Serum Sulfate and Brain Function in Diabetic EncephalopathyNot yet recruitingNCT07837258
- Influencing Factors of Cerebrovascular Disease and Cognition in Hemodialysis PatientsRecruitingNCT044334551 country
- taVNS + CCT for Neurocognitive RehabRecruitingNCT07517237Not applicable1 country
- Brain Heath Service for Prevention of ADNot yet recruitingNCT07834528Not applicable
- Predicting Pre-dementiaRecruitingNCT075161191 country
- Cognition and Affective Research in ChinaNot yet recruitingNCT078332671 country
- A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)RecruitingNCT07589595Phase 24 countries
- Efficacy and Safety of Photobiomodulation Therapy in Patients With Mild Cognitive Impairment and Mild Alzheimer's DiseaseRecruitingNCT07835399Not applicable1 country
- COG+OT Telerehabilitation for Adults With Subjective Cognitive ComplaintsNot yet recruitingNCT07743229Not applicable1 country
- SYNERGIC-2 Trial (SYNchronizing, Exercises and Remedies to GaIn Cognition@Home)RecruitingNCT05375513Not applicable1 country
- First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD)RecruitingNCT07216066Phase 12 countries
- Music for Pain and DementiaRecruitingNCT07602283Not applicable1 country
- Improving Neurological Health With Acetylcholine Via Neuroplasticity-based Computerized Exercise in Mild Cognitive ImpairmentRecruitingNCT07243600Not applicable1 country
- Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease StudiesRecruitingNCT07177352Phase 315 countries
- Comparing Two Acute Care Transition Programs for Older Adults and Their Family CaregiversRecruitingNCT07661355Not applicable1 country
- Microbiome in Aging of Gut and BrainRecruitingNCT077994021 country
- The Cardiovascular-Cognitive Health InitiativeRecruitingNCT07829380Not applicable1 country
- VisMemoPD Protocol: an Observational Pilot Study on Spatial and Topographical Memory in Patients With Parkinson's Disease and ParkinsonismNot yet recruitingNCT078279631 country
- PET Imaging of Cyclooxygenases in Neurodegenerative Brain DiseaseRecruitingNCT04396873Phase 11 country
- The Cognitive Protective Effect of VR-based Cognitive Training in Type 2 Diabetes Patients With Mild Cognitive ImpairmentRecruitingNCT07650318Not applicable1 country
- Adaptango Performance PRocess for Older Adults Community reHabilitationNot yet recruitingNCT07824128Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)RecruitingNCT06976203Phase 317 countries
- Dyadic Management Intervention in Older People With Co-occurring Cognitive Impairment and Diabetes as a Supplementary Approach to Chronic Diseases Self-Management ProgramRecruitingNCT07496359Not applicable1 country
- Probiotic Impact on Cognitive Performance, and Metabolic Outcomes in Overweight Young Adults With Impaired Glucose RegulationRecruitingNCT07073781Not applicable1 country
- Percepta for Cognitive OptimizationRecruitingNCT07612449Not applicable1 country
- Effects of an Exercise Snacking Intervention on Cognitive Function in Patients With Mild Cognitive Impairment: A Nationwide Multicenter Randomized Controlled TrialNot yet recruitingNCT07822867Not applicable
- Characterization of Dysmorphology in Subjects With Creatine Transporter DeficiencyRecruitingNCT056009461 country
- InRAD Observational StudyRecruitingNCT0721370014 countries
- An Insole and Ankle Device for Monitoring Cognitive Decline in Individuals at Risk for Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD)Not yet recruitingNCT07127133Not applicable1 country
- Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis UseRecruitingNCT05445180Not applicable1 country
- Efficacy and Safety Study of Digital Cognitive Training and PCSK9 Inhibitor-Enhanced Lipid-lowering Strategy in Patients With Intracranial Atherosclerotic Stenosis: A 2x2 Factorial, Randomized, Parallel-Group, Multicenter TrialNot yet recruitingNCT07605130Phase 41 country