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Cognitive Dysfunction clinical trials

The registry lists 3,872 studies for Cognitive Dysfunction across more than 10 countries. 1,119 are recruiting or about to start. 1,911 of them are mainly about Cognitive Dysfunction (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 2 narrower conditions too, such as Postoperative Cognitive Complications: 4,122 studies, 1,178 open.

ClinicalTrials.gov finds 5,333 studies for Cognitive Dysfunction. How that becomes 3,870 here

This page counts the studies the registry files under Cognitive Dysfunction, and those it files under no condition that list Cognitive Dysfunctionthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 5,333Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −250Filed under a narrower condition, counted on its own pagePostoperative Cognitive Complications 221 · Chemotherapy-Related Cognitive Impairment 26
  3. −85List Cognitive Dysfunction as a condition, but the registry did not file them under itMost often written as “Vascular Cognitive Impairment” (14), “Amnestic Mild Cognitive Impairment” (7), and “Post-stroke Cognitive Impairment” (6). The registry filed them under other conditions only, most often Alzheimer Disease (25) and Stroke (13).
  4. −1,131Match it another way491 name it in the title, 45 in a keyword, and 595 by a synonym or other text the search reads.
  5. 3,867Counted here and found by its search81 of them list Cognitive Dysfunction in their own words; the registry filed them under no condition.
  6. +3
    Counted here, but its search does not find them
  7. 3,870The count on this page

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Status

Completed
1,828
Recruiting
750
Status unknown
445
Not yet recruiting
283
Active, not recruiting
231
Terminated
158

Phase

Phase 2
382
Phase 1
159
Phase 3
137
Phase 4
130
Early Phase 1
38

Where

United States
1,418
China
309
Canada
223
France
189
Italy
174
Spain
161

Who runs them

VA Office of Research and Development (35) · Johns Hopkins University (34) · University of California, San Francisco (32) · Massachusetts General Hospital (32) · Wake Forest University Health Sciences (28) · Chang Gung Memorial Hospital (26) · University of Pennsylvania (24) · Emory University (24)

What is being tested here

Drugs under test in Cognitive Dysfunction studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Dexmedetomidine4012
Metformin3210
Ginkgo biloba extract317
Lacteol303
Memantine2515
Insulin2111
Methylphenidate217
Nicotinamide-beta-riboside206
Melatonin204
Atorvastatin203

Drug classes tested here Cholinesterase inhibitors 4 open · Stimulants 4 open · SGLT2 inhibitors 3 open · Antimuscarinics 3 open · Reverse transcriptase inhibitors 2 open

Coming up

30phase 3 studies under way
414studies finish main data collection within a year6 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 750 Cognitive Dysfunction studies recruiting now, 362 (48%) set no upper age limit and 143 (19%) stop at 75 or younger. 46 (6%) take children under 18. 16 (2%) are for women only and 1 (<1%) for men only; 259 (35%) take healthy volunteers.

Recruiting studies that take each age, of 750
AgeWomenMen
1033 (4%)31 (4%)
18238 (32%)231 (31%)
30264 (35%)255 (34%)
40305 (41%)293 (39%)
50439 (59%)426 (57%)
65684 (91%)672 (90%)
75655 (87%)646 (86%)
85532 (71%)523 (70%)

Across all 3,872 studies, recruiting or not: 21% stop at 75 or younger and 13% at 65; 5% take children; 3% are for women only and 1% for men only; 35% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Cognitive Dysfunction studies take

Of 186 phase 2 interventional studies under Cognitive Dysfunction, half reached primary completion within 44 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 127 mo13–49 · 80 studies17 mo7–40 · 26 studies43 mo16–64 · 54 studies
Phase 1/234 mo12–52 · 25 studies——
Phase 244 mo22–62 · 186 studies24 mo14–39 · 41 studies53 mo29–64 · 145 studies
Phase 344 mo33–63 · 49 studies——
Phase 455 mo20–69 · 51 studies—55 mo27–69 · 43 studies
Interventional, no phase27 mo12–50 · 1,511 studies15 mo7–35 · 69 studies27 mo13–51 · 1,442 studies
Observational47 mo21–118 · 543 studies—49 mo22–118 · 504 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting10

Show 5 more

Results posted4

Stopped4

Newly registered33

Show 28 more

Studies

Recruiting first, then most recently updated. Showing 50 of 3,872. Browse all 3,872 → or search them.