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Heart Valve Diseases clinical trials

The registry lists 554 studies for Heart Valve Diseases across more than 10 countries. 164 are recruiting or about to start. 223 of them are mainly about Heart Valve Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 13 narrower conditions too, such as Aortic Valve Stenosis: 2,770 studies, 862 open.

ClinicalTrials.gov finds 2,970 studies for Heart Valve Diseases. How that becomes 552 here

This page counts the studies the registry files under Heart Valve Diseases, and those it files under no condition that list Heart Valve Diseasesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 2,970Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −2,106Filed under a narrower condition, counted on its own pageAortic Valve Stenosis 902 · Mitral Valve Insufficiency 363 · Cardiomyopathy, Hypertrophic 342 · Tricuspid Valve Insufficiency 154 · Aortic Valve Disease 137 · Aortic Valve Insufficiency 48 · 6 more
  3. −8List Heart Valve Diseases as a condition, but the registry did not file them under itMost often written as “Rheumatic Valvular Heart Disease” (2), “Valvular Heart Disease Stenosis and Regurgitation” (2), and “Cardiac Surgery for Rheumatic Valvular Heart Disease” (1). The registry filed them under other conditions only, most often Gastroesophageal Reflux (3) and Renal Insufficiency (1).
  4. −304Match it another way8 name it in the title and 296 by a synonym or other text the search reads.
  5. 552The count on this page6 of them list Heart Valve Diseases in their own words; the registry filed them under no condition.

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Status

Completed
234
Recruiting
118
Status unknown
76
Not yet recruiting
40
Active, not recruiting
34
Terminated
31

Phase

Phase 4
33
Phase 2
25
Phase 3
16
Phase 1
8
Early Phase 1
1

Where

United States
110
China
67
Germany
65
Italy
48
France
48
United Kingdom
42

Who runs them

Edwards Lifesciences (20) · Abbott Medical Devices (18) · Yonsei University (12) · Medtronic Cardiovascular (10) · Konkuk University Medical Center (10) · Assiut University (7) · China National Center for Cardiovascular Diseases (6) · Second Affiliated Hospital, School of Medicine, Zhejiang University (6)

What is being tested here

Drugs under test in Heart Valve Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Apixaban112
Simvastatin102
Azithromycin101
Iron isomaltoside 1000101
Prothrombin complex concentrate101
Sultamicillin101
Losartan101
Esketamine101
Rivaroxaban024
Dexmedetomidine014

Drug classes tested here Factor Xa inhibitors 1 open · Statins 1 open

Coming up

2phase 3 studies under way
46studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 118 Heart Valve Diseases studies recruiting now, 93 (79%) set no upper age limit and 10 (8%) stop at 75 or younger. 16 (14%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 15 (13%) take healthy volunteers.

Recruiting studies that take each age, of 118
AgeWomenMen
1014 (12%)14 (12%)
18103 (87%)103 (87%)
30109 (92%)109 (92%)
40109 (92%)109 (92%)
50110 (93%)110 (93%)
65114 (97%)114 (97%)
75113 (96%)113 (96%)
85106 (90%)106 (90%)

Across all 554 studies, recruiting or not: 14% stop at 75 or younger and 6% at 65; 11% take children; 1% are for women only and <1% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Heart Valve Diseases studies take

Of 153 interventional studies with no phase under Heart Valve Diseases, half reached primary completion within 30 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase30 mo16–55 · 153 studies30 mo18–55 · 45 studies28 mo16–53 · 108 studies
Observational67 mo23–212 · 115 studies—67 mo23–212 · 95 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 14, 2026.

Started recruiting4

Results posted1

Newly registered4

Studies

Recruiting first, then most recently updated. Showing 50 of 554. Browse all 554 → or search them.