Pulmonary Valve Insufficiency clinical trials
The registry lists 31 studies for Pulmonary Valve Insufficiency across more than 10 countries. 8 are recruiting or about to start. 15 of them are mainly about Pulmonary Valve Insufficiency (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-28.
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Who runs them
Edwards Lifesciences (8) · Venus MedTech (HangZhou) Inc. (2) · Medtronic Cardiovascular (2) · Charite University, Berlin, Germany (2) · Taewoong Medical Co., Ltd. (2) · UMC Utrecht (1) · University of California, San Francisco (1) · Dr. Miguel Angel Maluf (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Nov 2026Harmony TPV Post-Approval Study · Medtronic Cardiovascular
- Dec 2026COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction · Edwards Lifesciences
- Dec 2026Sodium-Glucose Cotransporter 2 Inhibitors for Repaired Tetralogy of Fallot Patients for Enhancement of Cardio-Pulmonary Status Trial · The University of Hong Kong
- Jul 2027Harmony TPV EMEA PMS · Medtronic Cardiovascular
Who these studies take
Of the 7 Pulmonary Valve Insufficiency studies recruiting now, 5 (71%) set no upper age limit and 0 (0%) stop at 75 or younger. 4 (57%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (29%) | 2 (29%) |
| 18 | 7 (100%) | 7 (100%) |
| 30 | 7 (100%) | 7 (100%) |
| 40 | 7 (100%) | 7 (100%) |
| 50 | 7 (100%) | 7 (100%) |
| 65 | 7 (100%) | 7 (100%) |
| 75 | 7 (100%) | 7 (100%) |
| 85 | 6 (86%) | 6 (86%) |
Across all 31 studies, recruiting or not: 10% stop at 75 or younger and 3% at 65; 81% take children; 0% are for women only and 0% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 31 of 31. search them.
- Sodium-Glucose Cotransporter 2 Inhibitors for Repaired Tetralogy of Fallot Patients for Enhancement of Cardio-Pulmonary Status TrialRecruitingNCT06668389Phase 41 country
- PULSTA TPV Observational StudyNot yet recruitingNCT077472076 countries
- COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve DysfunctionRecruitingNCT02744677Not applicable1 country
- Harmony TPV EMEA PMSRecruitingNCT06906926Not applicable8 countries
- Berlin Registry of Right Heart InterventionsRecruitingNCT045701631 country
- Feasibility Study to Evaluate the Safety of the Autologous GrOwnValve Transcatheter Pulmonary Heart ValveRecruitingNCT05809856Not applicable1 country
- VenusP-Valve Pivotal Study (PROTEUS STUDY)RecruitingNCT06010563Not applicable1 country
- Early Versus Later Re-valving in Tetralogy of Fallot With Free Pulmonary RegurgitationRecruitingNCT04084132Not applicable1 country
- ALTERRA: SAPIEN 3 THV With the Alterra Adaptive PrestentActive, not recruitingNCT03130777Not applicable1 country
- ALTERRA Post-Approval StudyActive, not recruitingNCT053783862 countries
- Harmony TPV Post-Approval StudyActive, not recruitingNCT05077774Not applicable2 countries
- PULSTA Transcatheter Pulmonary Valve Pre-Approval StudyActive, not recruitingNCT03983512Not applicable6 countries
- Evaluation of the GORE PV1 Device in Patients With Pulmonary Valve DysfunctionActive, not recruitingNCT03441971Not applicable1 country
- COMPASSION S3 Post-Approval StudyActive, not recruitingNCT048607651 country
- COMPASSION XT PAS - Post-approval Study of the SAPIEN XT THV in Patients With Pulmonary Valve DysfunctionCompletedNCT029873871 country
- The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical StudyActive, not recruitingNCT02979587Not applicable3 countries
- COMMENCE Pulmonary: Clinical Evaluation of Edwards Pericardial Aortic Bioprosthesis (Model 11000A) for Pulmonary Valve ReplacementCompletedNCT02656290Not applicable1 country
- Implantation of the Venus P-Valve™ in the Pulmonic Position in Patients With Native Outflow TractsStatus unknownNCT02846753Not applicable
- A Feasibility Study to Evaluate the Safety and Short-term Effectiveness of Transcatheter Pulmonary Valve (TPV)CompletedNCT02555319Not applicable1 country
- Stent Implantation of Polyurethane Expandable Valve, by Catheter, in Patients With Pulmonary Valve DysfunctionStatus unknownNCT05289622Not applicable1 country
- Right Ventricle Remodeling After Pulmonary Valve Replacement and Percutaneous Pulmonary Valve InsertionCompletedNCT050902281 country
- Right Ventricular Diastolic Function in Chronic Adverse RV Loading And Congenital Heart DiseaseStatus unknownNCT03471936Not applicable1 country
- Prospective Evaluation of Programmed Ventricular Stimulation Before Pulmonary Valve Replacement in Patients With Tetralogy of FallotStatus unknownNCT042054611 country
- COMPASSION - COngenital Multicenter Trial of Pulmonic VAlve Regurgitation Studying the SAPIEN InterventIONal THVCompletedNCT00676689Not applicable1 country
- Pulmonic Valve REplacement Multi-discIpline EMEA RegistryCompletedNCT013561089 countries
- Pulmonary Artery Repair With Covered StentsCompletedNCT01824160Not applicable1 country
- CryoValve SG Pulmonary Human Heart Valve Post Clearance StudyCompletedNCT010924421 country
- Multi-center Trial of Percutaneous Pulmonary Valve Implantation With Venus-pStatus unknownNCT02590679Phase 2/31 country
- Tetralogy of Fallot Seed GrantCompletedNCT007228261 country
- Comparison of Two Pulmonary Valve Replacement Methods to Treat Tetralogy of FallotCompletedNCT00112320Not applicable1 country
- Pulmonary Valve Replacement in Large Right Ventricular Outflow TractCompletedNCT00259207Phase 31 country