Pulmonary Valve Insufficiency clinical trials
The registry lists 31 studies for Pulmonary Valve Insufficiency across more than 10 countries. 8 are recruiting or about to start. 15 of them are mainly about Pulmonary Valve Insufficiency (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-28.
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Who runs them
Edwards Lifesciences (8) · Taewoong Medical Co., Ltd. (2) · Medtronic Cardiovascular (2) · Venus MedTech (HangZhou) Inc. (2) · Charite University, Berlin, Germany (2) · Shanghai Zhongshan Hospital (1) · Dr. Miguel Angel Maluf (1) · University of California, San Francisco (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Nov 2026Harmony TPV Post-Approval Study · Medtronic Cardiovascular
- Dec 2026COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction · Edwards Lifesciences
- Dec 2026Sodium-Glucose Cotransporter 2 Inhibitors for Repaired Tetralogy of Fallot Patients for Enhancement of Cardio-Pulmonary Status Trial · The University of Hong Kong
- Jul 2027Harmony TPV EMEA PMS · Medtronic Cardiovascular
Who these studies take
Of the 7 Pulmonary Valve Insufficiency studies recruiting now, 5 (71%) set no upper age limit and 0 (0%) stop at 75 or younger. 4 (57%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (29%) | 2 (29%) |
| 18 | 7 (100%) | 7 (100%) |
| 30 | 7 (100%) | 7 (100%) |
| 40 | 7 (100%) | 7 (100%) |
| 50 | 7 (100%) | 7 (100%) |
| 65 | 7 (100%) | 7 (100%) |
| 75 | 7 (100%) | 7 (100%) |
| 85 | 6 (86%) | 6 (86%) |
Across all 31 studies, recruiting or not: 10% stop at 75 or younger and 3% at 65; 81% take children; 0% are for women only and 0% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 31 of 31. search them.
- Sodium-Glucose Cotransporter 2 Inhibitors for Repaired Tetralogy of Fallot Patients for Enhancement of Cardio-Pulmonary Status TrialRecruitingNCT06668389Phase 41 country
- PULSTA TPV Observational StudyNot yet recruitingNCT077472076 countries
- COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve DysfunctionRecruitingNCT02744677Not applicable1 country
- Harmony TPV EMEA PMSRecruitingNCT06906926Not applicable8 countries
- Berlin Registry of Right Heart InterventionsRecruitingNCT045701631 country
- Feasibility Study to Evaluate the Safety of the Autologous GrOwnValve Transcatheter Pulmonary Heart ValveRecruitingNCT05809856Not applicable1 country
- VenusP-Valve Pivotal Study (PROTEUS STUDY)RecruitingNCT06010563Not applicable1 country
- Early Versus Later Re-valving in Tetralogy of Fallot With Free Pulmonary RegurgitationRecruitingNCT04084132Not applicable1 country
- ALTERRA: SAPIEN 3 THV With the Alterra Adaptive PrestentActive, not recruitingNCT03130777Not applicable1 country
- ALTERRA Post-Approval StudyActive, not recruitingNCT053783862 countries
- Harmony TPV Post-Approval StudyActive, not recruitingNCT05077774Not applicable2 countries
- PULSTA Transcatheter Pulmonary Valve Pre-Approval StudyActive, not recruitingNCT03983512Not applicable6 countries
- Evaluation of the GORE PV1 Device in Patients With Pulmonary Valve DysfunctionActive, not recruitingNCT03441971Not applicable1 country
- COMPASSION S3 Post-Approval StudyActive, not recruitingNCT048607651 country
- COMPASSION XT PAS - Post-approval Study of the SAPIEN XT THV in Patients With Pulmonary Valve DysfunctionCompletedNCT029873871 country
- The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical StudyActive, not recruitingNCT02979587Not applicable3 countries
- COMMENCE Pulmonary: Clinical Evaluation of Edwards Pericardial Aortic Bioprosthesis (Model 11000A) for Pulmonary Valve ReplacementCompletedNCT02656290Not applicable1 country
- Implantation of the Venus P-Valve™ in the Pulmonic Position in Patients With Native Outflow TractsStatus unknownNCT02846753Not applicable
- A Feasibility Study to Evaluate the Safety and Short-term Effectiveness of Transcatheter Pulmonary Valve (TPV)CompletedNCT02555319Not applicable1 country
- Stent Implantation of Polyurethane Expandable Valve, by Catheter, in Patients With Pulmonary Valve DysfunctionStatus unknownNCT05289622Not applicable1 country
- Right Ventricle Remodeling After Pulmonary Valve Replacement and Percutaneous Pulmonary Valve InsertionCompletedNCT050902281 country
- Right Ventricular Diastolic Function in Chronic Adverse RV Loading And Congenital Heart DiseaseStatus unknownNCT03471936Not applicable1 country
- Prospective Evaluation of Programmed Ventricular Stimulation Before Pulmonary Valve Replacement in Patients With Tetralogy of FallotStatus unknownNCT042054611 country
- COMPASSION - COngenital Multicenter Trial of Pulmonic VAlve Regurgitation Studying the SAPIEN InterventIONal THVCompletedNCT00676689Not applicable1 country
- Pulmonic Valve REplacement Multi-discIpline EMEA RegistryCompletedNCT013561089 countries
- Pulmonary Artery Repair With Covered StentsCompletedNCT01824160Not applicable1 country
- CryoValve SG Pulmonary Human Heart Valve Post Clearance StudyCompletedNCT010924421 country
- Multi-center Trial of Percutaneous Pulmonary Valve Implantation With Venus-pStatus unknownNCT02590679Phase 2/31 country
- Tetralogy of Fallot Seed GrantCompletedNCT007228261 country
- Comparison of Two Pulmonary Valve Replacement Methods to Treat Tetralogy of FallotCompletedNCT00112320Not applicable1 country
- Pulmonary Valve Replacement in Large Right Ventricular Outflow TractCompletedNCT00259207Phase 31 country