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Tricuspid Valve Insufficiency clinical trials

The registry lists 227 studies for Tricuspid Valve Insufficiency across more than 10 countries. 110 are recruiting or about to start. 190 of them are mainly about Tricuspid Valve Insufficiency (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

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Status

Recruiting
82
Completed
58
Status unknown
25
Not yet recruiting
23
Active, not recruiting
23
Enrolling by invitation
5

Phase

Phase 3
5
Phase 4
3
Phase 1
1
Phase 2
1

Where

United States
60
Germany
51
Italy
32
China
26
France
19
Korea, Republic of
15

Who runs them

Edwards Lifesciences (14) · LMU Klinikum (8) · Abbott Medical Devices (7) · Mayo Clinic (5) · Tau-MEDICAL Co., Ltd. (4) · TRiCares (4) · Shanghai Huihe Medical Technology Co., Ltd (4) · Charite University, Berlin, Germany (4)

What is being tested here

Drugs under test in Tricuspid Valve Insufficiency studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Hydroxyethyl Starch Derivatives102
Vericiguat101
Enavogliflozin011
Carvedilol011
Empagliflozin011
Liposomal Bupivacaine011
Bupivacaine011
Tolvaptan001
Torsemide001
Dapagliflozin001

Drug classes tested here SGLT2 inhibitors 3

Coming up

1phase 3 study under way
32studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 82 Tricuspid Valve Insufficiency studies recruiting now, 68 (83%) set no upper age limit and 0 (0%) stop at 75 or younger. 7 (9%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (2%) take healthy volunteers.

Recruiting studies that take each age, of 82
AgeWomenMen
106 (7%)6 (7%)
1871 (87%)71 (87%)
3074 (90%)74 (90%)
4074 (90%)74 (90%)
5077 (94%)77 (94%)
6582 (100%)82 (100%)
7582 (100%)82 (100%)
8582 (100%)82 (100%)

Across all 227 studies, recruiting or not: 4% stop at 75 or younger and 2% at 65; 6% take children; 0% are for women only and 0% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Tricuspid Valve Insufficiency studies take

Of 86 interventional studies with no phase under Tricuspid Valve Insufficiency, half reached primary completion within 38 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase38 mo23–58 · 86 studies38 mo27–70 · 55 studies—
Observational57 mo35–106 · 46 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 14, 2026.

Started recruiting4

Results posted1

Newly registered2

Studies

Recruiting first, then most recently updated. Showing 50 of 227. Browse all 227 → or search them.