Drug
Losartan clinical trials
Also written Cozaar, MK0954 and HGP1405.
- studies test it
- 246
- open now
- 27
- in phase 3
- 43
- first study started
- 1990
Keep track of what changes. Save the Losartan studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
- Cozaar
- 60
Studies by the year they started
240 studies that test it; most in 2008 (18); 1 more planned to start later
| Year | Studies |
|---|---|
| 1990 | 1 |
| 1991 | 2 |
| 1992 | 1 |
| 1995 | 1 |
| 1997 | 1 |
| 1999 | 2 |
| 2000 | 3 |
| 2001 | 2 |
| 2002 | 3 |
| 2003 | 6 |
| 2004 | 9 |
| 2005 | 9 |
| 2006 | 6 |
| 2007 | 13 |
| 2008 | 18 |
| 2009 | 10 |
| 2010 | 12 |
| 2011 | 10 |
| 2012 | 5 |
| 2013 | 13 |
| 2014 | 12 |
| 2015 | 5 |
| 2016 | 5 |
| 2017 | 7 |
| 2018 | 13 |
| 2019 | 7 |
| 2020 | 18 |
| 2021 | 7 |
| 2022 | 6 |
| 2023 | 8 |
| 2024 | 12 |
| 2025 | 5 |
| 2026 | 8 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 15
- Phase 1
- 40
- Phase 2
- 55
- Phase 3
- 43
- Phase 4
- 60
- No phase
- 44
What it is tested for
Each study’s main condition, where its own words name it.
- COVID-19
- 10
Who runs them
Industry 53 · Other 193
Organon and Co (9) · Hanmi Pharmaceutical Company Limited (8) · University of Oxford (7) · University of Electronic Science and Technology of China (7) · Massachusetts General Hospital (6) · Merck Sharp & Dohme LLC (6) · Children's Hospital Medical Center, Cincinnati (4) · Boehringer Ingelheim (4)
Often tested with
Tested in the same studies.
Amlodipine (25) · Hydrochlorothiazide (20) · Telmisartan (8) · Lisinopril (6) · Atenolol (5) · Captopril (5) · Metoprolol (5) · Benazepril (5)
Studies
Open first, then newest update. How each study uses Losartan is read from its arms, and is right about nine times in ten.
Testing it · 246
- Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)Enrolling by invitationPhase 4Baylor Research InstituteNCT07547878Written as Cozaar
- Losartan and Paclitaxel in Platinum Resistant Ovarian CancerNot yet recruitingPhase 2Massachusetts General HospitalNCT07265739Written as losartan
- A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)RecruitingPhase 3Mayo ClinicNCT06150560Written as Losartan
- A Phase 1 Clinical Trial to Evaluate the Safety and the Pharmacokinetic Drug-Drug Interaction Between HUC2A-752-A and HUC2A-752-B in Healthy AdultsNot yet recruitingPhase 1Huons Co., Ltd.NCT07784621Written as Losartan (COZZAR®)
- Losartan + Sunitinib in Treatment of OsteosarcomaRecruitingPhase 1University of Colorado, DenverNCT03900793Written as Losartan
- Secondhand Tobacco Smoke and Cardiovascular DiseaseRecruitingPhase 4University of California, San FranciscoNCT04715568Written as Losartan
- Comparative Effectiveness of Dual Antihypertensive Regimens in Patients After Percutaneous Coronary InterventionRecruitingNot applicableNational Medical Research Center for Therapy and Preventive MedicineNCT07683585Written as Losartan + Hydrochlorothiazide
- Role of Sympathetic Overactivity and Angiotensin II in PTSD and CVRecruitingPhase 2Emory UniversityNCT02560805Written as Losartan
- Losartan for Corneal FibrosisRecruitingNot applicableUniversidad Autonoma de Nuevo LeonNCT07449000Written as Topical losartan
- Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite AthletesEnrolling by invitationNot applicableEnhanced Emirates LimitedNCT07568574Written as Losartan
- Investigation of the Effectiveness of Exercise and Anti-Fibrotic Approaches in Frozen ShoulderRecruitingNot applicableIstanbul UniversityNCT07513350Written as Losartan
- Losartan, Pembrolizumab and Stereotactic Body Radiation Therapy for the Treatment of Patients With Locally Recurrent, Refractory or Oligometastatic Head and Neck Squamous Cell CarcinomaRecruitingPhase 1University of California, DavisNCT06211335Written as Losartan
- Losartan to Improve Outcomes After Multi-ligament Knee InjuryRecruitingPhase 2Brigham and Women's HospitalNCT06933706Written as losartan 25 mg
- Study to Use Oral Losartan to Decrease the Risk of Postoperative Scarring Following (ACL) ReconstructionNot yet recruitingPhase 4Rush University Medical CenterNCT07135687Written as Losartan
- Sacubitril/Allisartan for Hypertensive Patients With Overweight or ObesityNot yet recruitingPhase 4Jing LiuNCT07241338Written as sacubitril/allisartan
- Exploration of Postoperative Adjuvant Therapy for HCC Patients With Positive TBNot yet recruitingPhase 4Second Affiliated Hospital of Xi'an Jiaotong UniversityNCT07160361Written as Lenvatinib + losartan
- Effect of Losartan on the Neurohumoral Axis and Ventricular Remodeling of Patients With Severe Aortic Regurgitation Undergoing Valve Surgery.RecruitingPhase 4Vitor Emer Egypto RosaNCT07099859Written as Losartan 50 mg
- Combined Blood Pressure Medication and Activity Scheduling for Low MoodRecruitingEarly Phase 1University of OxfordNCT07017023Written as Losartan with BA
- Losartan and Emotional Processing in Young PeopleRecruitingEarly Phase 1University of OxfordNCT06636812Written as Losartan potassium
- Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis.RecruitingPhase 2University of Kansas Medical CenterNCT06364176Written as Losartan
See all 246 studies that test Losartan →
Given in every arm · 25 — Losartan is usual care beside what is tested
- Combination Immunotherapy Treatment for Locally Advanced Unresectable or Metastatic, PD-L1 Negative (CPS<10), gBRCA Negative, Triple Negative Breast Cancer Including BreakVax ImmunoTreatment (Designed and Manufactured Per Patient), Chemotherapy and Anti PD-1 TherapyNot yet recruitingPhase 1/2BreakBio CorpNCT07762703Written as Losartan and aspirin
- Combination Immunotherapy Treatment for Glioblastoma Including BreakVax ImmunoTreatment (Designed and Manufactured Per Patient), Chemotherapy and Anti PD-1 TherapyNot yet recruitingPhase 1/2BreakBio CorpNCT07762716Written as Losartan and aspirin
- Determinants of Warfarin MetabolismRecruitingNot applicableHadassah Medical OrganizationNCT00162474Written as Losartan & Hydrochlorothiazide
- NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic CancerActive, not recruitingPhase 2OHSU Knight Cancer InstituteNCT04539808Written as Losartan Potassium
- Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid TumorsCompletedPhase 1PfizerNCT03864042Written as losartan
- Effects of Amlodipine and Other Blood Pressure Lowering Agents on Microvascular FunctionTerminatedPhase 3Ludwig-Maximilians - University of MunichNCT03082014Written as Losartan
- Study to Evaluate the Effect on Improvement of LVH by the Control of BP in Hypertension Patients With AV DiseaseCompletedPhase 4Hanmi Pharmaceutical Company LimitedNCT03666351Written as Losartan
- Metformin's Effect on Drug Metabolism in Patients With Type 2 DiabetesTerminatedPhase 1University of Southern DenmarkNCT04504045Written as Losartan
- Patiromer in the Treatment of Hyperkalemia in Patients With Hypertension and Diabetic Nephropathy (AMETHYST-DN)CompletedPhase 2Relypsa, Inc.NCT01371747Written as losartan
- Phase 4, Vedolizumab-4002 Post-marketing, Disease-Drug-Drug Interaction StudyWithdrawnPhase 4TakedaNCT02760615Written as Losartan
- Losartan in Hypertensive Men and Women With Sleep Apnea Before and on Continuous Positive Airway Pressure (CPAP) TreatmentCompletedPhase 4Skaraborg HospitalNCT00701428Written as Losartan
- Chinese Medicine Treat for Hypertensive Renal InjuryStatus unknownPhase 2/3Jiangsu Province Hospital of Traditional Chinese MedicineNCT04078711Written as Losartan 100Mg Tab
- Effect of Add-on Spironolactone to Losartan Versus Losartan Alone on Peritoneal Membrane Among Peritoneal Dialysis PatientsStatus unknownPhase 4Chiang Mai UniversityNCT03953950Written as Losartan
- Tissue Pharmacokinetics of Intraoperative Gemcitabine in Resectable Adenocarcinoma of the PancreasTerminatedEarly Phase 1M.D. Anderson Cancer CenterNCT01276613Written as Losartan
- A Study of the Pharmacokinetics and Pharmacodynamics of MK1809 (1809-001)(COMPLETED)CompletedPhase 1Merck Sharp & Dohme LLCNCT01033318Written as Comparator: Losartan
- Resveratrol's Effects in Diabetic NephropathyCompletedEarly Phase 1Shiraz University of Medical SciencesNCT02704494Written as Losartan
- Intervention Using Vitamin D for Elevated Urinary Albumin Treated With Losartan in Diabetes (IDEAL)TerminatedPhase 2/3Weill Cornell Medical College in QatarNCT02410005Written as Losartan
- Add-on Pentoxifylline to Losartan Versus Increasing Dose of Losartan on NT-PRO BNP in Type 2 Diabetics With NephropathyCompletedPhase 4Tehran University of Medical SciencesNCT03006952Written as Losartan
- Randomized Controlled Trial of Renal Denervation for Resistant HypertensionStatus unknownPhase 3Shanghai WiseGain Medical Devices Co., Ltd.NCT02900729Written as Amlodipine, losartan potassium and hydrochlorothiazide
- Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery StenosisTerminatedPhase 4Russian Cardiology Research and Production CenterNCT00805311Written as atorvastatin, aspirin, losartan, amlodipine
Showing 20 of 25.
As the comparator · 30 — what is tested is compared with Losartan
- The GranStone TrialNot yet recruitingPhase 2/3Martin Blomberg JensenNCT07828002Written as Losartan 100 mg
- Efficacy and Safety of Telmisartan Compared With LosartanRecruitingPhase 4Chong Kun Dang PharmaceuticalNCT06431477Written as Losartan
- A Clinical Trial to Evaluate the Blood Pressure Control of Telmisartan or Losartan in Essential Hypertensive Patients With Metabolic SyndromeNot yet recruitingPhase 4Chong Kun Dang PharmaceuticalNCT05843162Written as Losartan
- A Study of Losartan Compared to Losartan/HCTZ in Pediatric Patients With Hypertension (0954A-327)TerminatedPhase 3Organon and CoNCT00447603Written as losartan potassium
- MK-0954A in Japanese Patients With Essential Hypertension Not Adequately Controlled With Losartan (MK-0954A-352)CompletedPhase 3Organon and CoNCT01307046Written as Losartan
- The ENRGISE (ENabling Reduction of Low-Grade Inflammation in SEniors) Pilot StudyCompletedPhase 2University of FloridaNCT02676466Written as Losartan
- Prevention of Diabetes and HypertensionTerminatedPhase 4Istituto Auxologico ItalianoNCT00456963Written as Losartan Tablets
- Azilsartan in Patients With Diabetic Kidney Disease and HypertensionStatus unknownNot applicableSecond Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT05753696Written as Losartan
- Antihypertensive Effect of Different Doses of Rostafuroxin in Comparison With LosartanCompletedPhase 2Windtree TherapeuticsNCT03217825Written as Losartan
- A Phase 2 Study to Assess Dose-response Relationship of HCP1803 in Patients With Essential HypertensionCompletedPhase 2Hanmi Pharmaceutical Company LimitedNCT03897868Written as Losartan
- The Effects of Mycophenolate Mofetil (MMF) on Renal Outcomes in Advanced Immunoglobulin A (IgA) Nephropathy PatientsCompletedNot applicableFan Fan HouNCT01854814Written as Losartan
- A Randomized, Double-blind, Active Control, Parallel Group, Titration, Multicenter Study to Evaluate the Efficacy and Safety of FimasartanCompletedPhase 3Boryung Pharmaceutical Co., LtdNCT02620306Written as Losartan 50mg~100mg
- A Phase 3 Study to Compare the Efficacy and Safety of Co-administered HGP0608, HGP0904 and HCP1306 Versus HCP1701 in Patients With Hypertension and DyslipidemiaCompletedPhase 3Hanmi Pharmaceutical Company LimitedNCT04074551Written as Losartan
- Efficacy and Safety Evaluating Study to Compare Kanarb (Fimasartan) and Cozaar® (Losartan) in Adult Patients With Grade I-II Arterial HypertensionCompletedPhase 3R-PharmNCT02248961Written as Losartan
- Efficacy and Safety of Candesartan Associated With Chlorthalidone Versus Losartan Associated With Hydrochlorothiazide (Hyzaar®) in Essential Hypertension ControlWithdrawnPhase 3EMSNCT02521246Written as Losartan+hydrochlorothiazide
- Efficacy and Safety of Candesartan Associated With Chlorthalidone in Essential Arterial Hypertension ControlWithdrawnPhase 3EMSNCT02521233Written as losartan+hydrochlorothiazide
- Comparison of Blood Pressure Lowering Effect Between Fimasartan and LosartanStatus unknownPhase 4Chuncheon Sacred Heart HospitalNCT02958631Written as Losartan
- AVE7688 in Patients With Mild to Moderate Blood PressureCompletedPhase 2/3SanofiNCT00284128Written as Losartan-potassium
- Efficacy and Safety of HL-040XC in Essential Hypertension and HyperlipidemiaCompletedPhase 3HanAll BioPharma Co., Ltd.NCT01541943Written as Losartan
- Safety and Pharmacokinetics of Besylsartan Tablet in Healthy Male SubjectCompletedPhase 1Huons Co., Ltd.NCT02504606Written as Amosartan
Showing 20 of 30.
Codes
What other systems call Losartan · ClinicalTrials.gg INT008725
- MeSH (NLM) D019808LosartanConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) JMS50MPO89LOSARTANConfirmed FDA, NLM, Wikidata
- RxNorm 52175Confirmed FDA, Wikidata
- Wikidata Q410074losartanConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C66869LosartanOne source FDA
- DrugBank DB00678One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D019808 | Losartan | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | JMS50MPO89 | LOSARTAN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 52175 | — | Confirmed FDA, Wikidata |
| Wikidata | Q410074 | losartan | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C66869 | Losartan | One source FDA |
| DrugBank | DB00678 | — | One source Wikidata |
Also registered as losartan potassium (UNII 3ST302B24A · RxNorm 203160).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.