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Aortic Valve Stenosis clinical trials

The registry lists 1,025 studies for Aortic Valve Stenosis across more than 10 countries. 293 are recruiting or about to start. 858 of them are mainly about Aortic Valve Stenosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 3 narrower conditions too, such as Cardiomyopathy, Hypertrophic: 1,424 studies, 423 open.

ClinicalTrials.gov finds 1,483 studies for Aortic Valve Stenosis. How that becomes 1,024 here

This page counts the studies the registry files under Aortic Valve Stenosis, and those it files under no condition that list Aortic Valve Stenosisthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 1,483Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −381Filed under a narrower condition, counted on its own pageCardiomyopathy, Hypertrophic 347 · Williams Syndrome 29 · Aortic Valve, Calcification of 5
  3. −20List Aortic Valve Stenosis as a condition, but the registry did not file them under itMost often written as “Moderate Aortic Valve Stenosis” (3), “Aortic Stenosis Symptomatic” (2), and “Aortic Stenosis Disease” (2). The registry filed them under other conditions only, most often Mitral Valve Insufficiency (3) and Aortic Valve Disease (3).
  4. −58Match it another way35 name it in the title, 1 in a keyword, and 22 by a synonym or other text the search reads.
  5. 1,024The count on this page34 of them list Aortic Valve Stenosis in their own words; the registry filed them under no condition.

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Status

Completed
418
Recruiting
209
Status unknown
138
Active, not recruiting
83
Not yet recruiting
67
Terminated
54

Phase

Phase 4
56
Phase 3
37
Phase 2
29
Phase 1
5
Early Phase 1
4

Where

Germany
190
United States
189
France
130
Italy
117
United Kingdom
107
Netherlands
106

Who runs them

Edwards Lifesciences (41) · Abbott Medical Devices (26) · Medtronic Cardiovascular (20) · Institut für Pharmakologie und Präventive Medizin (17) · Boston Scientific Corporation (16) · University Hospital, Montpellier (14) · Medtronic Bakken Research Center (12) · Insel Gruppe AG, University Hospital Bern (12)

What is being tested here

Drugs under test in Aortic Valve Stenosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Ferric carboxymaltose203
Spironolactone212
Inclisiran222
Ticagrelor125
Ataciguat113
Dexmedetomidine112
Dapagliflozin102
Ezetimibe122
Eplerenone102
Methylprednisolone102

Drug classes tested here SGLT2 inhibitors 2 open · Angiotensin receptor blockers (ARBs) 2 open · Mineralocorticoid receptor antagonists (MRAs) 2 open · P2Y12 inhibitors 1 open · Statins 1 open

Coming up

8phase 3 studies under way
69studies finish main data collection within a year2 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 209 Aortic Valve Stenosis studies recruiting now, 163 (78%) set no upper age limit and 9 (4%) stop at 75 or younger. 25 (12%) take children under 18. 0 (0%) are for women only and 1 (<1%) for men only; 14 (7%) take healthy volunteers.

Recruiting studies that take each age, of 209
AgeWomenMen
1022 (11%)22 (11%)
18153 (73%)153 (73%)
30162 (78%)162 (78%)
40164 (78%)165 (79%)
50172 (82%)173 (83%)
65191 (91%)192 (92%)
75201 (96%)202 (97%)
85192 (92%)193 (92%)

Across all 1,025 studies, recruiting or not: 2% stop at 75 or younger and 1% at 65; 15% take children; <1% are for women only and <1% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Aortic Valve Stenosis studies take

Of 24 phase 4 interventional studies under Aortic Valve Stenosis, half reached primary completion within 43 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 443 mo26–70 · 24 studies——
Interventional, no phase33 mo18–72 · 288 studies29 mo16–54 · 111 studies47 mo23–79 · 177 studies
Observational42 mo23–86 · 242 studies34 mo21–47 · 37 studies45 mo23–120 · 205 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting5

Newly registered6

Show 1 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,025. Browse all 1,025 → or search them.