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Mitral Valve Insufficiency clinical trials

The registry lists 468 studies for Mitral Valve Insufficiency across more than 10 countries. 164 are recruiting or about to start. 363 of them are mainly about Mitral Valve Insufficiency (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.

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Status

Completed
153
Recruiting
122
Status unknown
69
Active, not recruiting
37
Not yet recruiting
36
Terminated
23

Phase

Phase 4
21
Phase 2
17
Phase 1
16
Phase 3
9
Early Phase 1
2

Where

United States
117
Germany
81
Italy
63
China
55
Canada
47
France
42

Who runs them

Edwards Lifesciences (32) · Abbott Medical Devices (28) · Polares Medical SA (8) · Michele De Bonis (7) · China National Center for Cardiovascular Diseases (6) · Sun Yat-sen University (6) · NeoChord (6) · HighLife SAS (5)

What is being tested here

Drugs under test in Mitral Valve Insufficiency studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Hydroxyethyl Starch Derivatives102
Valsartan111
Rivaroxaban101
Aspirin101
Phenylephrine101
Propofol013
Isoflurane013
Sevoflurane013
Metoprolol012
Ertugliflozin011

Drug classes tested here Angiotensin receptor blockers (ARBs) 1 open · Inhaled anesthetics 3

Coming up

1phase 3 study under way
37studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest

Who these studies take

Of the 122 Mitral Valve Insufficiency studies recruiting now, 101 (83%) set no upper age limit and 6 (5%) stop at 75 or younger. 13 (11%) take children under 18. 0 (0%) are for women only and 1 (1%) for men only; 1 (1%) take healthy volunteers.

Recruiting studies that take each age, of 122
AgeWomenMen
1013 (11%)13 (11%)
18103 (84%)104 (85%)
30113 (93%)114 (93%)
40113 (93%)114 (93%)
50114 (93%)115 (94%)
65118 (97%)119 (98%)
75117 (96%)118 (97%)
85112 (92%)113 (93%)

Across all 468 studies, recruiting or not: 7% stop at 75 or younger and 4% at 65; 9% take children; <1% are for women only and <1% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Mitral Valve Insufficiency studies take

Of 143 interventional studies with no phase under Mitral Valve Insufficiency, half reached primary completion within 56 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase56 mo25–108 · 143 studies59 mo25–144 · 90 studies—
Observational57 mo26–192 · 84 studies—57 mo26–192 · 72 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting6

Show 1 more

Results posted1

Newly registered4

Studies

Recruiting first, then most recently updated. Showing 50 of 468. Browse all 468 → or search them.