Mitral Valve Prolapse clinical trials
The registry lists 47 studies for Mitral Valve Prolapse across more than 10 countries. 11 are recruiting or about to start. 26 of them are mainly about Mitral Valve Prolapse (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-03.
Get an email when these change. Save the Mitral Valve Prolapse studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Abbott Medical Devices (5) · Edwards Lifesciences (5) · NeoChord (4) · Ospedale San Raffaele (2) · Centro Cardiologico Monzino (2) · Central Hospital, Nancy, France (2) · Oslo University Hospital (2) · CSD Labs GmbH (2)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Jun 2027PRIMARY Ancillary Substudy · Annetine Gelijns
- Nov 2027STretch and Myocardial Characterization in Arrythmogenic Mitral Valve Prolapse-2 · Central Hospital, Nancy, France
Who these studies take
Of the 10 Mitral Valve Prolapse studies recruiting now, 9 (90%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (10%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (10%) | 1 (10%) |
| 18 | 8 (80%) | 8 (80%) |
| 30 | 10 (100%) | 10 (100%) |
| 40 | 10 (100%) | 10 (100%) |
| 50 | 10 (100%) | 10 (100%) |
| 65 | 10 (100%) | 10 (100%) |
| 75 | 10 (100%) | 10 (100%) |
| 85 | 9 (90%) | 9 (90%) |
Across all 47 studies, recruiting or not: 15% stop at 75 or younger and 6% at 65; 17% take children; 0% are for women only and 0% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
Studies
Recruiting first, then most recently updated. Showing 47 of 47. search them.
- Korea VHD Echo Study: Surveillance of Aortic, Mitral & Tricuspid Patients - Insights From Real-world PracticeRecruitingNCT070686331 country
- Mitral Valve Prolapse Arrhythmic RiskRecruitingNCT078308881 country
- Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapseRecruitingNCT063411661 country
- AI-Based Shape and Function Analysis of Mitral Valve Prolapse Using 3D UltrasoundRecruitingNCT073848711 country
- Ventricular Arrhythmias in Patients Undergoing Mitral Valve SurgeryRecruitingNCT062554571 country
- A Study of Mitral Annular Disjunction in Mitral Valve Prolapse Patients and Arrhythmia RiskNot yet recruitingNCT067417091 country
- Patient-Centered Approach for Treatment Decisions in Mitral Valve ProlapseRecruitingNCT067385371 country
- Genetic Basis of Mitral Valve ProlapseRecruitingNCT017192111 country
- Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral PlastyRecruitingNCT031135521 country
- Mitral Valve Prolapse, Arrhythmias and Mitral Valve SurgeryRecruitingNCT055628041 country
- Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery SystemRecruitingNCT041906023 countries
- Effect and Safety of Flecainide and Metoprolol Versus Metoprolol Alone to Suppress Ventricular Arrhythmias in Arrhythmic Mitral Valve ProlapseActive, not recruitingNCT05631730Phase 31 country
- PRIMARY Ancillary SubstudyActive, not recruitingNCT07103733Not applicable3 countries
- Arrhythmic Mitral Valve Prolapse Detection Using Long-term Ambulatory Rhythm MonitoringCompletedNCT06378996Not applicable1 country
- STretch and Myocardial Characterization in Arrythmogenic Mitral Valve Prolapse-2Active, not recruitingNCT04852731Not applicable1 country
- The Role of cardIac magNeTic rEsonance in surGical Decision Making in Patients With Severe pRimAry miTral rEgurgitationActive, not recruitingNCT07366723Not applicable1 country
- Mitro-annular Disjunction in Cardiac Magnetic ResonanceCompletedNCT064365731 country
- CE Mark Study for the Harpoon Medical Device in PolandCompletedNCT02432196Not applicable1 country
- Safety and Early Feasibility Study of the Harpoon Medical Device (EFS)CompletedNCT02771275Not applicable1 country
- CE Mark Study for the Harpoon Medical DeviceCompletedNCT02768870Not applicable2 countries
- Operative Mitral Valve Reconstruction in Functional mv Insufficiency With Reduced Systolic Ventricle FunctionCompletedNCT034701551 country
- European FIH Study - NeoChord Transcatheter Mitral Repair System for Symptomatic Mitral RegurgitationStatus unknownNCT05425628Not applicable
- Myocardial Characterization of Arrhythmogenic Mitral Valve Prolapse (STAMP: STretch and Myocardial Characterization in Arrhythmogenic Mitral Valve Prolapse)CompletedNCT02879825Not applicable1 country
- Determinants of the Progression and Outcome of Mitral RegurgitationStatus unknownNCT018350543 countries
- Genetic and Phenotypic Characteristics of Mitral Valve ProlapseStatus unknownNCT038844261 country
- Erector Spinae Plane Block for Minimally Invasive Mitral Valve SurgeryStatus unknownNCT04770961Not applicable1 country
- Minimally Invasive or Conventional Edge-To-Edge Repair for Severe Mitral Regurgitation Due to Bileaflet Prolapse in Barlow's Disease: Does the Surgical Approach Have an Impact on the Long-term Results?CompletedNCT04002648
- Neochordae Technique in Mitral Valve RepairStatus unknownNCT04299334Phase 11 country
- Myocardial Protection in Minimally Invasive Mitral Valve SurgeryCompletedNCT04231903
- Safety and Performance Study of the Harpoon Mitral Valve Repair SystemTerminatedNCT03285724Not applicable1 country
- Primary Mitral Regurgitation RepairStatus unknownNCT040676351 country
- St. Jude Medical Percutaneous Mitral Valve Repair StudyCompletedNCT01500148Phase 11 country
- The Canadian Mitral Research Alliance (CAMRA) Trial CardioLink-2Status unknownNCT02552771Not applicable1 country
- Real World Expanded Multicenter Study of the MitraClip® System (REALISM)CompletedNCT01931956Not applicable1 country
- EVEREST II Pivotal Study High Risk Registry (HRR)CompletedNCT01940120Not applicable1 country
- Pivotal Study of a Percutaneous Mitral Valve Repair SystemCompletedNCT00209274Not applicable1 country
- Feasibility Study of a Percutaneous Mitral Valve Repair System.CompletedNCT00209339Phase 1/21 country
- Patient Specific Mitral Valve Modeling for Surgical Planning and TrainingStatus unknownNCT03609931
- Automatic Differentiation of Innocent and Pathologic Murmurs in PediatricsCompletedNCT025123411 country
- Automated Algorithm Based Analysis of Phonocardiograms of NewbornsCompletedNCT021054801 country
- Using Pulse Counter Vigileo-Flotrac System in Transapical Off-pump Minimally Invasive Mitral Valve RepairStatus unknownNCT035062171 country
- NeoChord TACT Post-Market Surveillance RegistryCompletedNCT017840555 countries
- Exercise Capacity Evaluation in Patients With Non-rheumatic Mitral Valve Prolapse (MVP)Status unknownNCT024994191 country
- V-Chordal Adjustable System for Chordal Replacement in Mitral Valve Insufficiency Due to Leaflet ProlapseTerminatedNCT01415947Phase 21 country
- Safety and Performance Study of the NeoChord DeviceCompletedNCT01777815Not applicable4 countries
- Mitral Valve Prolapse (MVP) - France StudyCompletedNCT00799565Not applicable1 country
- Cardiac Output Pulmonary Arterial Catheter Compared to FloWave™ 1000CompletedNCT006653011 country