Drug
Rivaroxaban clinical trials
Also written Xarelto, BAY 59-7939 and JNJ-39039039.
- studies test it
- 303
- open now
- 60
- in phase 3
- 106
- first study started
- 2002
Keep track of what changes. Save the Rivaroxaban studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
303 studies that test it; most in 2020 (28)
| Year | Studies |
|---|---|
| 2002 | 1 |
| 2004 | 6 |
| 2005 | 1 |
| 2006 | 7 |
| 2007 | 5 |
| 2008 | 2 |
| 2009 | 2 |
| 2010 | 5 |
| 2011 | 5 |
| 2012 | 13 |
| 2013 | 19 |
| 2014 | 17 |
| 2015 | 24 |
| 2016 | 19 |
| 2017 | 17 |
| 2018 | 14 |
| 2019 | 14 |
| 2020 | 28 |
| 2021 | 24 |
| 2022 | 19 |
| 2023 | 22 |
| 2024 | 18 |
| 2025 | 13 |
| 2026 | 8 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 5
- Phase 1
- 44
- Phase 2
- 49
- Phase 3
- 106
- Phase 4
- 86
- No phase
- 28
What it is tested for
Each study’s main condition, where its own words name it.
- COVID-19
- 11
Who runs them
Industry 77 · Other 226
Bayer (44) · Janssen Research & Development, LLC (9) · Ottawa Hospital Research Institute (7) · Insel Gruppe AG, University Hospital Bern (6) · Assistance Publique - Hôpitaux de Paris (6) · Population Health Research Institute (5) · Ottawa Heart Institute Research Corporation (4) · Centre Hospitalier Universitaire de Saint Etienne (4)
Often tested with
Tested in the same studies.
Apixaban (33) · Aspirin (25) · Dabigatran (21) · Warfarin (17) · Edoxaban (12) · Enoxaparin (11) · Clopidogrel (8) · Ticagrelor (6)
Studies
Open first, then newest update. How each study uses Rivaroxaban is read from its arms, and is right about nine times in ten.
Testing it · 303
- Model-informed Dose Optimization for Rivaroxaban in Children With Giant Coronary Artery Aneurysm After Kawasaki DiseaseRecruitingPhase 4Children's Hospital of Fudan UniversityNCT06978439Written as Rivaroxaban (Xarelto)
- Comparison of DOACs and LMWH for Thromboprophylaxis After Total Knee ArthroplastyRecruitingNot applicableMilitary Hospital of TunisNCT07869615Written as Rivaroxaban
- HIP Fracture Oral thromboPROphylaxis (Hip PRO Pilot)RecruitingPhase 2University of CalgaryNCT05775965Written as Rivaroxaban 10mg
- COmparison of Bleeding Risk Between Rivaroxaban and Apixaban in Patients With Atrial FibrillationRecruitingPhase 4Ottawa Hospital Research InstituteNCT04642430Written as Rivaroxaban
- Comparing the Safety and Efficacy of Apixaban and RivaroxabanRecruitingPhase 4VA Office of Research and DevelopmentNCT06953726Written as Rivaroxaban
- Comparison of Aspirin Alone Versus Low-Dose Rivaroxaban Plus Aspirin in Chronic Limb-Threatening IschemiaRecruitingEarly Phase 1King Edward Medical UniversityNCT07832578Written as Low-Dose Rivaroxaban Plus Aspirin,
- Rivaroxaban vs Enoxaparin After Cesarean Section: Laboratory Thromboprophylaxis OutcomesRecruitingNot applicableWolfson Medical CenterNCT07820670Written as Rivaroxaban
- Personalizing Thromboprophylaxis for Patients With Peripheral Artery DiseaseRecruitingNot applicableMassachusetts General HospitalNCT07613840Written as Rivaroxaban
- Comparison of Clopidogrel-based Antiplatelet Agent Treatment and Aspirin Plus Low Dose Rivaroxaban TherapyRecruitingPhase 4Seoul National University Bundang HospitalNCT07796217Written as Aspirin and low-dose rivaroxaban
- Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in IntraCranial Atherosclerotic diseaSe (CATIS- ICAS)Not yet recruitingPhase 3Population Health Research InstituteNCT07468448Written as Rivaroxaban
- Direct Oral Anticoagulants (Rivaroxaban and Apixaban) in Patients With Liver CirrhosisRecruitingPhase 1Insel Gruppe AG, University Hospital BernNCT04874428Written as Rivaroxaban 10 mg Oral Tablet
- NOAC Therapy Guided by PARIS Risk Score and D-dimer in Patients With ACS After PCIRecruitingPhase 4China National Center for Cardiovascular DiseasesNCT05638867Written as Aspirin + Clopidogrel + Rivaroxaban
- Impact of Bromocriptine on Clinical Outcomes for Peripartum CardiomyopathyRecruitingPhase 4Dennis M. McNamara, MD, MSNCT05180773Written as Rivaroxaban
- Long-term Anticoagulation With Oral Factor Xa Inhibitor Versus Vitamin K Antagonist After Mechanical Aortic Valve ReplacementRecruitingPhase 4Joon Bum KimNCT04258488Written as Rivaroxaban Oral Tablet
- Rivaroxaban for Children Aged Over 2 Years With Giant Coronary Artery Aneurysms After Kawasaki DiseaseRecruitingPhase 4Children's Hospital of Fudan UniversityNCT05643651Written as Rivaroxaban Oral Tablet [Xarelto]
- Thromboprophylaxis in Lower Limb ImmobilisationRecruitingPhase 3Queen Mary University of LondonNCT06370273Written as Rivaroxaban
- RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTingRecruitingPhase 3University Hospital, AngersNCT06195540Written as Rivaroxaban 10 MG
- Chronic Anticoagulation With a Reduced Dose Regimen of Rivaroxaban in End-stage Renal Disease PatientsRecruitingPhase 3University Hospital, ToursNCT05410275Written as Rivaroxaban
- THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE)RecruitingPhase 4Imperial College LondonNCT05735639Written as Rivaroxaban
- Anti-CoagulaTion on Left Ventricular Thrombus After ST Segment Elevation Myocardial InfarctionRecruitingNot applicableJilin UniversityNCT05892042Written as Rivaroxaban 15 MG [Xarelto]
See all 303 studies that test Rivaroxaban →
Given in every arm · 13 — Rivaroxaban is usual care beside what is tested
- Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery DiseaseRecruitingPhase 3Regeneron PharmaceuticalsNCT07318610Written as Rivaroxaban
- Effects of VMX-C001 on the Anticoagulant Effect of Different Forms of HeparinCompletedPhase 1VarmX B.V.NCT06517563Written as Rivaroxaban
- Phase 2 Study of Rivaroxaban Reversal by Ciraparantag as Measured by WBCTCompletedPhase 2Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc.NCT03172910Written as Rivaroxaban
- A Study to Assess the Independent Effects of 4-Factor Prothrombin Complex Concentrate and Tranexamic Acid on Bleeding/Pharmacodynamics in Healthy ParticipantsCompletedPhase 1Janssen Scientific Affairs, LLCNCT02561923Written as Rivaroxaban
- Study of Intravenous VMX-C001 in Healthy Subjects and in Combination With Selected Direct Oral Anticoagulants in Healthy Older SubjectsCompletedPhase 1VarmX B.V.NCT05152420Written as Rivaroxaban
- A Healthy Volunteer Pharmacokinetics (PK)/Pharmacodynamics (PD), Safety and Tolerability Study of Andexanet in Healthy Japanese and Caucasian SubjectsCompletedPhase 2Portola PharmaceuticalsNCT03310021Written as Rivaroxaban
- Combined Topical Tranexamic Acid With Floseal® in Total Knee ArthroplastyCompletedPhase 4Chang Gung Memorial HospitalNCT03328832Written as rivaroxaban (10mg)
- Rivaroxaban With Diosmin in Long-term Treatment of Deep Vein ThrombosisCompletedPhase 4Pirogov Russian National Research Medical UniversityNCT03413618Written as Rivaroxaban
- Rivaroxaban Hypericum TrialCompletedPhase 1Insel Gruppe AG, University Hospital BernNCT03796377Written as Rivaroxaban
- DUAL Antithrombotic Therapy in Patients With AF and ACSStatus unknownPhase 4Second Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT04023630Written as Rivaroxaban 15 MG Oral Tablet
- A Study to Assess the Effects of 2 Different Prothrombin Complex Concentrates on the Pharmacodynamics of Rivaroxaban in Healthy Adult VolunteersCompletedPhase 1Janssen Research & Development, LLCNCT01656330Written as Rivaroxaban 20 mg twice daily
- The Blood Saving Effect of Tranexamic Acid in Total Knee Arthroplasty With Rivaroxaban as ThromboprophylaxisCompletedPhase 4Chang Gung Memorial HospitalNCT02458729Written as rivaroxaban (10mg)
- Comparison of Topical and Infusion Tranexamic Acid After Total Knee ArthroplastyStatus unknownPhase 4Chang Gung Memorial HospitalNCT02453802Written as rivaroxaban (10mg)
As the comparator · 15 — what is tested is compared with Rivaroxaban
- Dabigatran vs. Oral Anti-Xa Inhibitors in S. Aureus BacteremiaRecruitingPhase 4McGill University Health Centre/Research Institute of the McGill University Health CentreNCT06650501Written as Rivaroxaban
- STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients With an Indication for Oral AnticoagulantRecruitingPhase 4Chinese Academy of Medical Sciences, Fuwai HospitalNCT06901466Written as Active Comparator: Rivaroxaban+Clopidogrel
- A Pilot Trial Comparing Full Dose Rivaroxaban to Prophylactic Dose Rivaroxaban in Patients With Superficial Vein Thrombosis in the LegRecruitingPhase 2/3Ottawa Hospital Research InstituteNCT06965998Written as Low dose rivaroxaban
- Bleeding Risk With Apixaban Versus Rivaroxaban in Acute Pulmonary EmbolismCompletedNot applicableCombined military hospital lahoreNCT07774273Written as Drug: Rivaroxaban
- VTE Prevention Following Total Hip and Knee ArthroplastyCompletedPhase 3Sudeep ShivakumarNCT04075240Written as Rivaroxaban 10 MG and acetylsalicylic acid 81 mg
- Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical TherapyCompletedPhase 4Charite University, Berlin, GermanyNCT03463317Written as Rivaroxaban
- Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial FibrillationActive, not recruitingPhase 2Anthos Therapeutics, Inc.NCT04755283Written as Rivaroxaban
- A Study to Evaluate the Efficacy and Safety of SHR-2004 Injection in Preventing Postoperative Venous Thromboembolism in Patients Undergoing Ovarian Cancer SurgeryCompletedPhase 2Beijing Suncadia Pharmaceuticals Co., LtdNCT06220123Written as Enoxaparin Sodium Injection; Rivaroxaban Tablets
- Assessment of Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban, or Aspirin Plus REGN9933, or Aspirin Plus REGN7508 in Healthy Adult ParticipantsCompletedPhase 1Regeneron PharmaceuticalsNCT06444178Written as Rivaroxaban
- Tinzaparin Lead-In to Prevent the Post-Thrombotic SyndromeTerminatedPhase 4Sunnybrook Health Sciences CentreNCT04794569Written as Rivaroxaban
- Efficacy and Safety of Apixaban in COVID-19 Coagulopathy Patients With Respiratory Severity Under Critical CareStatus unknownPhase 2Scotmann PharmaceuticalsNCT05088928Written as Rivaroxaban
- Better Adherence With New Oral Anticoagulant in Atrial Fibrillation : Effectiveness of a Personalized Education ProgramCompletedNot applicableUniversity Hospital, MontpellierNCT02422602Written as Xarelto
- Rivaroxaban for the Treatment of Symptomatic Isolated Distal Deep Vein ThrombosisStatus unknownPhase 3Walter AgenoNCT02722447Written as rivaroxaban
- Evaluation of WATCHMAN Left Atrial Appendage Occlusion Device in Patients With Atrial Fibrillation Versus RivaroxabanStatus unknownPhase 4Shulin WuNCT02549963Written as Rivaroxaban
- Single IV Administration of TB-402 for Prophylaxis of Venous Thromboembolic Events (VTE) After Total Hip Replacement SurgeryCompletedPhase 2ThromboGenicsNCT01344954Written as Rivaroxaban
Codes
What other systems call Rivaroxaban · ClinicalTrials.gg INT006609
- MeSH (NLM) D000069552RivaroxabanConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 9NDF7JZ4M3RIVAROXABANConfirmed FDA, NLM, Wikidata
- RxNorm 1114195Confirmed FDA, Wikidata
- Wikidata Q420262rivaroxabanConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C77995RivaroxabanOne source FDA
- DrugBank DB06228One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000069552 | Rivaroxaban | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 9NDF7JZ4M3 | RIVAROXABAN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1114195 | — | Confirmed FDA, Wikidata |
| Wikidata | Q420262 | rivaroxaban | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C77995 | Rivaroxaban | One source FDA |
| DrugBank | DB06228 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.