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Headache clinical trials

The registry lists 762 studies for Headache across more than 10 countries. 134 are recruiting or about to start. 286 of them are mainly about Headache (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.

ClinicalTrials.gov finds 2,612 studies for Headache. How that becomes 762 here

This page counts the studies the registry files under Headache, and those it files under no condition that list Headachethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 2,612Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −748List Headache as a condition, but the registry did not file them under itMost often written as “Cervicogenic Headache” (88), “Migraine Headache” (69), and “Tension-Type Headache” (68). The registry filed 31 of them under no condition at all, and the others under other conditions only, most often Migraine Disorders (215) and Post-Traumatic Headache (147).
  3. −1,103Match it another way168 name it in the title, 53 in a keyword, and 882 by a synonym or other text the search reads.
  4. 761Counted here and found by its search18 of them list Headache in their own words; the registry filed them under no condition.
  5. +1
    Counted here, but its search does not find them
  6. 762The count on this page

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Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

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Status

Completed
441
Recruiting
83
Status unknown
79
Terminated
50
Not yet recruiting
41
Withdrawn
32

Phase

Phase 3
102
Phase 2
82
Phase 4
64
Phase 1
28
Early Phase 1
3

Where

United States
324
Denmark
65
Turkey
63
Canada
40
Spain
36
Germany
33

Who runs them

Danish Headache Center (40) · Eli Lilly and Company (15) · Assiut University (9) · Amgen (9) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (8) · Pfizer (7) · Mayo Clinic (7) · Montefiore Medical Center (6)

What is being tested here

Drugs under test in Headache studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Lidocaine7315
Substance P202
Erenumab1816
Acetaminophen1111
Bupivacaine126
Dexamethasone115
Rimegepant125
Magnesium Sulfate133
Amitriptyline113
Zavegepant112

Drug classes tested here Local anesthetics 8 open · CGRP receptor antagonists 3 open · Corticosteroids 2 open · Serotonin receptor agonists 1 open · NSAIDs 21

Coming up

11phase 3 studies under way
47studies finish main data collection within a year4 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 83 Headache studies recruiting now, 30 (36%) set no upper age limit and 44 (53%) stop at 75 or younger. 10 (12%) take children under 18. 6 (7%) are for women only and 0 (0%) for men only; 14 (17%) take healthy volunteers.

Recruiting studies that take each age, of 83
AgeWomenMen
107 (8%)7 (8%)
1878 (94%)72 (87%)
3077 (93%)71 (86%)
4077 (93%)71 (86%)
5072 (87%)70 (84%)
6566 (80%)64 (77%)
7541 (49%)40 (48%)
8536 (43%)35 (42%)

Across all 762 studies, recruiting or not: 62% stop at 75 or younger and 54% at 65; 17% take children; 7% are for women only and 1% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Headache studies take

Of 31 phase 2 interventional studies under Headache, half reached primary completion within 20 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 119 mo1–26 · 15 studies——
Phase 220 mo12–36 · 31 studies——
Phase 318 mo13–47 · 30 studies17 mo13–31 · 21 studies—
Phase 425 mo17–28 · 26 studies——
Interventional, no phase14 mo6–38 · 193 studies—14 mo6–37 · 175 studies
Observational21 mo12–96 · 63 studies—21 mo12–96 · 55 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting1

Results posted1

Newly registered2

Studies

Recruiting first, then most recently updated. Showing 50 of 762. Browse all 762 → or search them.