Headache clinical trials
The registry lists 1,226 studies for Headache across more than 10 countries. 203 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Completed
- 705
- Status unknown
- 157
- Recruiting
- 120
- Terminated
- 86
- Not yet recruiting
- 68
- Withdrawn
- 45
Phase
- Phase 2
- 138
- Phase 3
- 124
- Phase 4
- 101
- Phase 1
- 53
- Early Phase 1
- 7
Where
- United States
- 438
- Denmark
- 125
- Turkey
- 70
- Egypt
- 60
- Spain
- 57
- Canada
- 50
Who runs them
Danish Headache Center (86) · Riphah International University (21) · Cairo University (19) · Assiut University (14) · Thomas Jefferson University (11) · Mayo Clinic (11) · Ain Shams University (11) · Norwegian University of Science and Technology (10)
Studies
Recruiting first, then most recently updated. Showing 50 of 1,226 — search for more.
- A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine HeadacheRecruitingNCT06473597Phase 41 country
- EMBRACE-OBS: Single-Site Observational Registry of Patient-Reported Outcomes Following MMA Embolization for MigraineRecruitingNCT076520341 country
- Familial Mediterranean Fever and Related Disorders: Genetics and Disease CharacteristicsRecruitingNCT000013731 country
- Multisite Advancement of Research on Chronic Posttraumatic HeadacheRecruitingNCT05620719Not applicable1 country
- Localized Injection of Lidocaine Via the Middle Meningeal Artery for Headache TreatmentRecruitingNCT07361549Phase 21 country
- Responding With Evidence and Access for Childhood HeadachesRecruitingNCT05889624Not applicable1 country
- Puberty, Testosterone, and Brain DevelopmentRecruitingNCT066700531 country
- Migraine Characteristics and Associated FactorsNot yet recruitingNCT07822386
- Tirzepatide in Idiopathic Intracranial Hypertension TrialRecruitingNCT07191873Phase 41 country
- Headache and Hormone Use Among Transgender Population in Thailand: A Cross-Sectional Online StudyNot yet recruitingNCT078174461 country
- MMA Infusion of Lidocaine for Treatment of Headache in Patients With Aneurysmal SAHNot yet recruitingNCT07816159Phase 2
- Inertial Sensors for Obstetrical Walking Epidural TrackingRecruitingNCT064717901 country
- Effect of Ultrasound-Guided Dry Needling Targeting Rectus Capitus Posterior Major on Individuals With HeadachesRecruitingNCT07309874Not applicable1 country
- Comprehensive Approach to Lifestyle Modification in Chronic MigraineNot yet recruitingNCT07802860Not applicable1 country
- A Pivotal Clinical Study to Evaluate the MySalvia System for the Treatment of Resistant MigraineRecruitingNCT07719608Not applicable1 country
- Immediate Neuromuscular Responses of the Obliquus Capitis Inferior Following Upper Cervical Manual TherapyRecruitingNCT07725198Not applicable1 country
- Assessment of the Efficacy of Medrol Dose Pack for Acute Post-Concussive HeadachesRecruitingNCT046857721 country
- Neuromodulation During the Prodrome to Prevent Disabling Migraine Attacks in YouthNot yet recruitingNCT07772427Not applicable1 country
- Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated HeadacheRecruitingNCT06621329Phase 2/31 country
- Visual Instillation of Sphenopalatine-block Intervention for ONgoing MigraineNot yet recruitingNCT07764783Phase 21 country
- CORRELATION BETWEEN FORWARD HEAD POSTURE, CERVICAL MUSCLES ENDURANCE, AND PROPRIOCEPTIVE FUCTIONS IN CERVICOGENIC HEADACHE AMONG LATE ADOLESCENT STUDENTS.Not yet recruitingNCT077638861 country
- Reflex Therapy of Temporomandibular DysfunctionsRecruitingNCT07321483Not applicable1 country
- Headache Education and Awareness vs. Daily Mindfulness Strategies - Understanding PainNot yet recruitingNCT07513662Not applicable1 country
- Headache Ear Auditory Dizziness Sinus (HEADS) RegistryRecruitingNCT077542661 country
- EFFECT OF ANODAL TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS) OF PRIMARY MOTOR CORTEX ON HEADACHE FREQUENCY IN PATIENTS WITH CHRONIC MIGRAINENot yet recruitingNCT07743814Phase 31 country
- App-based Breathing Program for Migraine ReliefEnrolling by invitationNCT07297901Not applicable1 country
- Zavegepant Intranasal Spray for the Acute Treatment of Episodic Cluster HeadacheNot yet recruitingNCT07714369Phase 21 country
- Lidocaine Infusion Treatment for Subarachnoid Hemorrhage HeadachesRecruitingNCT065828101 country
- Tear Biomarkers for MigraineNot yet recruitingNCT07690696
- Online Hatha Yoga Program as an Add-On Therapy for Episodic High-Frequency MigraineRecruitingNCT07694063Not applicable1 country
- IA Lidocaine and Methylprednisolone for Headache Associated With Subarachnoid HemorrhageRecruitingNCT07054801Phase 21 country
- BLOCK-SAH - PPF-Block for Post-SAH HeadacheRecruitingNCT06008795Phase 21 country
- Intravenous Lidocaine to Prevent Post-Fundal Pressure Headache During Cesarean SectionRecruitingNCT07661758Phase 31 country
- Study for Prevent Chronification Migraine Through Prediction of Response to Treatment With Anti-CGRP AntibodiesRecruitingNCT064596481 country
- Muscle Position and Dry Needling EfficacyRecruitingNCT07629141Not applicable1 country
- Placebo Impacts Sleep and Pain Modulation in Chronic PainRecruitingNCT06225817Not applicable1 country
- Utilization of 60-Day Peripheral Nerve Stimulation of the Occipital Nerves for the Treatment of HeadacheEnrolling by invitationNCT075535331 country
- Sequential, Multiple Assignment, Double Randomized Preference, Migraine Behavioral TrialNot yet recruitingNCT06170281Not applicable1 country
- Ultrasound Guided Infratemporal Sphenopalatine Ganglion Supravoltage Versus Standard Voltage Pulsed Radiofrequency for Pain Alleviation in Chronic Refractory Migraine.RecruitingNCT07500558Not applicable1 country
- RimegepAnt effectIvenesS and tolErability as Migraine Preventive TreatmentRecruitingNCT064098321 country
- An Open Label Study Assessing REN Treatment in Headache Management in Temporomandibular DisordersRecruitingNCT07639944Not applicable1 country
- Evaluation of the Migraceutics® Phase-Specific Dietary Supplement Regimen on Quality of Life, Work Productivity, and Biomarkers in Adult Migraineurs: The Migraceutics® START StudyNot yet recruitingNCT07634146Not applicable1 country
- Determining the Utility of a Behavioral Intervention in Chronic MigraineRecruitingNCT05415020Not applicable1 country
- Intranasal Sphenopalatine Ganglion Blockade for Headaches Following Aneurysmal Subarachnoid HemorrhageRecruitingNCT07116408Phase 41 country
- Bilateral Middle Meningeal Artery Lidocaine Infusion for Chronic Debilitating MigrainesRecruitingNCT07061847Phase 21 country
- New Methods for Evaluating Preventive Migraine TreatmentRecruitingNCT07071506Not applicable1 country
- Adolescent Lifestyle Medicine Headache StudyEnrolling by invitationNCT07373275Not applicable1 country
- Percutaneous Needle Electrolysis (PNE) on the Concha of the EarRecruitingNCT05662722Not applicable1 country
- Aerobic Exercise and Its Impact on Sensory, Musculoskeletal, and Psychosocial Aspects in MigraineRecruitingNCT06716489Not applicable1 country
- External Trigeminal Nerve Stimulation for Migraine Treatment in PregnancyRecruitingNCT067889771 country