Danish Headache Center: Headache trials

The registry lists 86 Headache studies with Danish Headache Center as lead sponsor. 6 are open to participants now and 0 have results posted.

Phase 1 3Phase 2 2Phase 3 2Phase 4 1No phase 79(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Amylin-Induced Migraine Attacks Without AuraNot yet recruitingNCT07340788Not applicable
• Muscle Function and Tenderness Differences in Headache PatientsEnrolling by invitationNCT06859463
• Safety and Efficacy of Botulinum Toxin A in Patients With Posttraumatic HeadacheRecruitingNCT06839118Phase 3
• Pathophysiology and Treatment of Cerebrospinal Hypotension Exploration StudyEnrolling by invitationNCT06805591
• Effects of Substance P on Headache Induction in Healthy IndividualsNot yet recruitingNCT06632080Not applicable
• Registry for Migraine - Structural and Functional MRI Before and After Erenumab TreatmentRecruitingNCT04674020Phase 4
• Muscle Function and Strength Training of the Neck and Shoulder in Migraine and Tension-type Headache Patients. A Singel Arm Open Label TrialActive, not recruitingNCT06112587Not applicable
• Hypersensitivity to Phosphodiesterase 3 Inhibition in Post-Traumatic HeadacheStatus unknownNCT05595993Not applicable
• Effect of Riocigaut on Cerebral Vasodilation and Headache Induction in Healthy VolunteersCompletedNCT05582811Not applicable
• The Involvement of ATP Sensitive Potassium Channel in Migraine Aura and Migraine Pain.Status unknownNCT05565001Not applicable
• Hypersensitivity to Opening of BKCa Channels in Post-Traumatic HeadacheStatus unknownNCT05378074Not applicable
• Hypersensitivity to PACAP-38 in Post-Traumatic HeadacheStatus unknownNCT05378061Not applicable
• Post-traumatic Headache Multidisciplinary StudyCompletedNCT05328635
• Improved Treatment Course for Patients With Migraine and Tension-type HeadacheCompletedNCT05278325Not applicable
• Hypersensitivity to Opening of ATP-Sensitive Potassium Channels in Post-Traumatic HeadacheCompletedNCT05243953Not applicable
• Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals With MigraineCompletedNCT05211050Not applicable
• The Effects of Levcromakalim in Patients With Cluster HeadacheCompletedNCT05093582Not applicable
• The Hemodynamic Effects of PACAP38 After Glibenclamide Administration in Healthy VolunteersCompletedNCT04960657Not applicable
• Effect of Ivabradine on Levcromakalim-Induced Symptoms in Individuals With Migraine Without Aura (ILIM)CompletedNCT04853797Not applicable
• Investigating the Frequency and Phenotype of Headaches Associated With Fasting During the Month of Ramadan.CompletedNCT04804995
• Headache Inducing Effect of NN414 in Migraine PatientsStatus unknownNCT04744129Not applicable
• The Effect of Adenosine on Cranial Hemodynamic, Headache and Migraine Induction Properties.CompletedNCT04577443Not applicable
• The Effect of Anti-calcitonin Gene-related Peptide (CGRP) Receptor Antibodies on the Headache Inducing Properties of CGRP and Cilostazol in Migraine PatientsStatus unknownNCT04452929Not applicable
• Investigation of Vasodilation and Intensity of Headache Triggered by Glucagon Like Peptide-1 in HumansStatus unknownNCT04232605Not applicable
• The Hemodynamic Effects of CGRP After Glibenclamide Administration in Healthy VolunteersCompletedNCT04231617Not applicable
• Multiomics After Cold Pressor Test of People Who Are Unable to Have HeadacheCompletedNCT04220580Not applicable
• Multiomics After Headache Provocation of People Who Are Unable to Have HeadacheCompletedNCT04218760Not applicable
• Headache Provocation of People Who Are Unable to Have HeadacheCompletedNCT04217668Not applicable
• Pain Perception of People Who Are Unable to Have HeadacheCompletedNCT04217616
• Jaw Muscle Function in Patients With Tension-type HeadacheStatus unknownNCT04196127
• Validation of the TMD Pain Screener in a Specialized Headache CenterCompletedNCT04193111
• Adrenomedullin Effect on Migraine Without PatientsCompletedNCT04111484Not applicable
• Endocrinological Profile in Patients With Medication-overuse Headache Before and After Withdrawal TherapyCompletedNCT04090333
• Headache Inducing Effect of Levcromakalim in Migraine With Aura PatientsCompletedNCT04012047Not applicable
• The Effects of a Long-lasting Infusion of Vasoactive Intestinal Peptide (VIP) on Headache, Cranial Hemodynamic and Autonomic Symptoms in Healthy VolunteersCompletedNCT03989817Not applicable
• Efficacy and Tolerability of Erenumab in the Prophylactic Treatment of Persistent Post-Traumatic HeadacheCompletedNCT03974360Phase 2
• The Effects of Maxipost (BMS 204352) on Cerebral Hemodynamic and Headache in Healthy Volunteers and Migraine PatientsCompletedNCT03887325Not applicable
• The Hemodynamics Effect of Glibenclamide on Levcromakalim Assessed by High Resolution Magnetic Resonance Angiography (MRA) Technique in a Randomized Double-blind Cross-over Placebo-controlled Study With Healthy VolunteersStatus unknownNCT03886922Not applicable
• PACAP38 Induced Headache, Migraine and Flushing in Patients With MigraineCompletedNCT03881644Not applicable
• PACAP38 Induced Headache and Rosacea-like Symptoms in Patients With RosaceaCompletedNCT03878784Not applicable
• PACAP-38 Infusion in Patients With Cluster HeadacheStatus unknownNCT03814226Not applicable
• Clinical Characteristics and Pathophysiology of Post-Traumatic HeadacheCompletedNCT03791515Not applicable
• Muscle Tenderness and Hardness in Migraine PatientsCompletedNCT03626805
• The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Technique in a Randomized, Double-blind Placebo-controlled Design in Healthy Volunteers.CompletedNCT03609008Not applicable
• The Role of Inflammation and Vasodilatation in PACAP38-induced Headache Using MRI on Healthy SubjectsCompletedNCT03585894Not applicable
• The Effect of PACAP27 on the Extra- and Intracerebral Arteries Assessed by Magnetic Resonance Angiography (MRA) on Healthy VolunteersCompletedNCT03560024Not applicable
• The Effect of Sumatriptan and Placebo on CGRP Induced HeadacheCompletedNCT03542357Not applicable
• PACAP27 Headache Properties in Migraine Without Aura PatientsCompletedNCT03471039Not applicable
• Sleep in Cluster Headache: Sleep Parameters in- and Outside a Cluster BoutCompletedNCT03439722
• The Effect of Sumatriptan and Placebo Injection on Cilostazol Induced HeadacheCompletedNCT03422796Not applicable
• Carbon Monoxide Headache Triggering Properties as Well as Effects on the Brain's Vessels and Blood FlowCompletedNCT03385174Not applicable
• Headache Inducing Effect of Cromakalim in Migraine PatientsCompletedNCT03228355Not applicable
• The Effect of Intravenous L-kynurenine (LKYN) on Cerebral Hemodynamics in Healthy VolunteersCompletedNCT03212430Phase 1
• Pretreatment With Sumatriptan on Cilostazol Induced Headache in Healthy VolunteersCompletedNCT03156920Not applicable
• Carbon Monoxide Migraine-inducing Effects in Patients With Migraine Without Aura.CompletedNCT03075020Not applicable
• Is Detoxification Needed in Medication-overuse Headache?Status unknownNCT02993289Not applicable
• Muscle Strength in Shoulder and Neck Muscles in Tension Type Headache Patients. Effect of Specific Strength TrainingCompletedNCT02984826Not applicable
• Comparison of Two Detoxification Protocols for Treatment of Medication-overuse HeadacheCompletedNCT02903329Not applicable
• Circadian Rhythm and Attack-timing in Episodic Cluster Headache Patients in- and Outside of Bout: an Actigraphic StudyCompletedNCT02853487
• Muscle Soreness and Stiffness in Patients With Chronic or Frequent Episodic Tension Type Headache.CompletedNCT02746250Not applicable
• Investigation of Vascular Inflammation in Migraine Using Molecular Nano-imaging and Black Blood Imaging MRICompletedNCT02549898Not applicable
• SPG Neurostimulation in Cluster PatientsCompletedNCT02510729Not applicable
• The Effect of Sumatriptan and Placebo on Cilostazol Induced HeadacheCompletedNCT02486276Not applicable
• The Effect of Sumatriptan and Placebo on Isosorbide-5-mononitrate Induced HeadacheCompletedNCT02485340Not applicable
• CGRP's Cluster Headache Inducing Abilities in Cluster Headache PatientsCompletedNCT02466334Not applicable
• Exercise in Migraine and Co-existing Tension-type Headache and Neck PainCompletedNCT02269501Not applicable
• Carbon Monoxide's Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood FlowCompletedNCT02066558Not applicable
• Migraine With Aura Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow by HypoxiaCompletedNCT01896167Not applicable
• The Headache Inducing Effects of Cilostazol on Migraine PatientsCompletedNCT01841827Not applicable
• Acetazolamide's Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood FlowCompletedNCT01750723Not applicable
• Natriuretic Peptide's Headache Inducing Characteristics and Effects on the Cerebral Blood FlowCompletedNCT01637662Not applicable
• Prostaglandin F2alpha in a Human Headache ModelCompletedNCT01327118Not applicable
• EP4-receptor Antagonism and Prostaglandin E2 (PGE2) in a Human Headache ModelCompletedNCT00957983Phase 1/2
• Carbachols Headache-inducing Effect and Changes in Cerebral Blood Flow in Migraine PatientsCompletedNCT00564408Not applicable
• Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic MigraineCompletedNCT00541736Not applicable
• PACAP38´s (Pituitary Adenylate Cyclase-Activating Polypeptide) Headache Inducing Characteristics and Effects on the Cerebral Blood FlowCompletedNCT00380263Not applicable
• Headache Inducing Characteristics and Possible Changes in Cerebral Blood Flow After Administration of PGE2CompletedNCT00374530Not applicable
• Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2.CompletedNCT00358839Not applicable
• Carbachol´s Headache Inducing Characteristics and Effects on the Cerebral Blood FlowCompletedNCT00357864
• Prophylactic Effect of Memantine in Chronic Tension-Type HeadacheCompletedNCT00315666Phase 3
• PGI2 Induced Headache and Cerebral Haemodynamics in Healthy VolunteersTerminatedNCT00291395Phase 1
• Hemodynamic and Headache-Inducing Effect of Intravenous Vasoactive Intestinal Peptide in MigraineursCompletedNCT00272896Not applicable
• Cortical Reorganisation in Patients With Primary Headache DisordersStatus unknownNCT00263991
• Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2CompletedNCT00257985Not applicable
• The Diameter of the Middle Cerebral Artery Measured With Magnetic Resonance AngiographyCompletedNCT00256802Not applicable
• Experimental Headache Induced by Vasoactive Intestinal PolypeptideCompletedNCT00255320Not applicable