Drug
Amitriptyline clinical trials
Also written Elavil.
- studies test it
- 72
- open now
- 9
- in phase 3
- 18
- first study started
- 1994
Keep track of what changes. Save the Amitriptyline studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
68 studies that test it; most in 2014 (6); 1 more planned to start later
| Year | Studies |
|---|---|
| 1994 | 1 |
| 1995 | 1 |
| 1996 | 2 |
| 1997 | 1 |
| 2000 | 1 |
| 2002 | 2 |
| 2004 | 1 |
| 2005 | 3 |
| 2006 | 4 |
| 2007 | 1 |
| 2008 | 5 |
| 2009 | 2 |
| 2010 | 1 |
| 2011 | 3 |
| 2012 | 2 |
| 2013 | 5 |
| 2014 | 6 |
| 2015 | 4 |
| 2016 | 2 |
| 2017 | 2 |
| 2018 | 2 |
| 2020 | 1 |
| 2021 | 3 |
| 2022 | 2 |
| 2023 | 4 |
| 2024 | 5 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 7
- Phase 2
- 23
- Phase 3
- 18
- Phase 4
- 18
- No phase
- 12
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 3 · Other 69
Mayo Clinic (3) · Wright State University (3) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Insel Gruppe AG, University Hospital Bern (2) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · Children's Hospital Medical Center, Cincinnati (2) · Boston Medical Center (2) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1)
Often tested with
Tested in the same studies.
Topiramate (6) · Gabapentin (6) · Paroxetine (4) · Duloxetine (4) · Ketamine (3) · Venlafaxine (3) · Escitalopram (3) · Pregabalin (3)
Studies
Open first, then newest update. How each study uses Amitriptyline is read from its arms, and is right about nine times in ten.
Testing it · 72
- Pilot Studies Blocking Injury-Induced MVP Release in Skin Using Topical AmitriptylineNot yet recruitingPhase 1Wright State UniversityNCT07716722Written as Amitriptyline
- Responding With Evidence and Access for Childhood HeadachesRecruitingNot applicableChildren's Hospital Medical Center, CincinnatiNCT05889624Written as Amitriptyline
- Pilot Studies Testing the Use of Oral Amitriptyline in Reducing Localized Burn Injury-induced Microvesicle Particle ReleaseNot yet recruitingPhase 1Wright State UniversityNCT07640061Written as Amitriptyline
- Amitriptyline for IBS-like Symptoms in Quiescent Crohn's DiseaseRecruitingPhase 2University of MichiganNCT07556718Written as Amitriptyline
- Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With RosaceaRecruitingPhase 2Wright State UniversityNCT06312813Written as Amitriptyline
- Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic CoughRecruitingPhase 2Mayo ClinicNCT05110144Written as Amitriptyline 25 MG
- Efficacy of Two Doses of Duloxetine & Amitriptyline in Interstitial Lung Disease-related CoughRecruitingPhase 2Mayo ClinicNCT05120934Written as Amitriptyline 25 MG
- Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary CareNot yet recruitingPhase 4Fundacio d'Investigacio en Atencio Primaria Jordi Gol i GurinaNCT06499116Written as Amitriptyline
- Efficacy of Flunarizine Vs Amitriptyline in Prophylaxis of Migraine ProphylaxisNot yet recruitingNot applicableShalamar Institute of Health SciencesNCT06162819Written as Amitriptyline
- Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed MigrainesTerminatedPhase 4Rutgers, The State University of New JerseyNCT02090998Written as Amitriptyline
- A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic PainTerminatedPhase 3Jocelyn FitzgeraldNCT05658874Written as Amitriptyline/Gabapentin
- Comparison of Amitriptyline to Lifestyle Modification as Intervention for Vestibular MigraineWithdrawnEarly Phase 1Vanderbilt University Medical CenterNCT06417684Written as Amitriptyline
- Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)CompletedPhase 3National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT00124306Written as Amitriptyline
- Amitriptyline for Repetitive Behaviors in Autism Spectrum DisordersTerminatedPhase 3University of Missouri, Kansas CityNCT04725383Written as amitriptyline
- Effect of Ketamine, Amitriptyline and Their Combination on ItchCompletedNot applicableAalborg UniversityNCT06245564Written as Amitriptyline
- Amitriptyline to Prevent Headache After Traumatic Brain InjuryCompletedPhase 2University of WashingtonNCT01856270Written as Amitriptyline
- EASE (Efficacy of ATX01 Study in Erythromelalgia)CompletedPhase 2AlgoTherapeutixNCT05917912Written as Amitriptyline Hydrochloride
- Amitriptyline and Paroxetine Treatment of Major DepressionCompletedPhase 3Central Institute of Mental Health, MannheimNCT01049347Written as amitriptyline
- To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With DiarrheaCompletedPhase 4Bahria UniversityNCT05867550Written as Amitriptyline Hydrochloride 25 MG
- Physiology of GERD and Treatment ResponseCompletedNot applicableUniversity of California, DavisNCT04292470Written as Amitriptyline
See all 72 studies that test Amitriptyline →
Given in every arm · 3 — Amitriptyline is usual care beside what is tested
- Physical Therapy as Adjuvant Treatment of Vulvodynia: a Randomized Controled TrialStatus unknownPhase 3University of Campinas, BrazilNCT02871661Written as Amitriptyline
- Interpersonal Psychotherapy for Treatment Resistant DepressionStatus unknownNot applicableHospital de Clinicas de Porto AlegreNCT01896349Written as amitriptyline
- Pediatric Chronic Headache TrialStatus unknownPhase 3Children's Hospital Medical Center, CincinnatiNCT00389038Written as Amitriptyline
As the comparator · 11 — what is tested is compared with Amitriptyline
- Nortriptyline Compared With Amitriptyline for Migraine Prevention at SQUHNot yet recruitingPhase 4Sultan Qaboos UniversityNCT07856056Written as Amitriptyline
- Comparing Migraine Preventive Therapies vs. Anti-CGRP Therapies for Tinnitus in Patients With Migraine (COMPACT-PM)Not yet recruitingPhase 4Stanford UniversityNCT07655440Written as Amitriptyline
- EA for BPS: an RCT and Study for Central MechanismRecruitingNot applicableThe Third Affiliated hospital of Zhejiang Chinese Medical UniversityNCT05279963Written as Amitriptyline
- Focal Microvibration and Chronic Lumbosacral Radicular PainNot yet recruitingNot applicableFederico II UniversityNCT06301061Written as Gabapentin; Pregabalin; Duloxetine; Amitriptyline
- Study to Evaluate the Interest of Qutenza in Patients With Head and Neck Cancer in Remission and With Sequelae Neuropathic Pain.CompletedPhase 2Institut Claudius RegaudNCT04704453Written as Amitriptyline (Laroxyl®)
- Mind and Body Approaches to Pain Reduction in Youth With MigraineCompletedPhase 2Children's Hospital Medical Center, CincinnatiNCT03472092Written as Amitriptyline
- Amitriptyline vs GON and SON Blocks in MigraineCompletedNot applicableDr. Lutfi Kirdar Kartal Training and Research HospitalNCT04750967Written as Amitriptyline
- Comparing Gabapentin and Amitriptyline for the Treatment of Neuropathic Pain in Children and AdolescentsCompletedPhase 3The Hospital for Sick ChildrenNCT00312260Written as Amitriptyline
- Safety and Efficacy Study Comparing ETS6103 With Amitriptyline in the Treatment of Major Depressive Disorder (MDD)CompletedPhase 2e-Therapeutics PLCNCT02014363Written as Amitriptyline
- Study With Amitriptylin to Evaluate the Efficacy of Melatonin in Treatment of MigraineCompletedPhase 3Hospital Israelita Albert EinsteinNCT01357031Written as Amitriptyline
- Comparative Efficacy and Tolerability of Quetiapine XR and Amitriptyline in the Treatment of FibromyalgiaCompletedPhase 4Universidad de GranadaNCT00766350Written as amitriptyline
Codes
What other systems call Amitriptyline · ClinicalTrials.gg INT006956
- MeSH (NLM) D000639AmitriptylineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 1806D8D52KAMITRIPTYLINEConfirmed FDA, NLM, Wikidata
- RxNorm 704Confirmed FDA, Wikidata
- Wikidata Q58397amitriptylineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C62005AmitriptylineOne source FDA
- DrugBank DB00321One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000639 | Amitriptyline | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 1806D8D52K | AMITRIPTYLINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 704 | — | Confirmed FDA, Wikidata |
| Wikidata | Q58397 | amitriptyline | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C62005 | Amitriptyline | One source FDA |
| DrugBank | DB00321 | — | One source Wikidata |
Also registered as amitriptyline hydrochloride (UNII 26LUD4JO9K · RxNorm 203168).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.