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Fatigue clinical trials

The registry lists 2,229 studies for Fatigue across more than 10 countries. 426 are recruiting or about to start. 780 of them are mainly about Fatigue (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 2 narrower conditions too, such as Mental Fatigue: 2,424 studies, 485 open.

ClinicalTrials.gov finds 3,609 studies for Fatigue. How that becomes 2,222 here

This page counts the studies the registry files under Fatigue, and those it files under no condition that list Fatiguethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 3,609Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −192Filed under a narrower condition, counted on its own pageMental Fatigue 136 · Compassion Fatigue 56
  3. −326List Fatigue as a condition, but the registry did not file them under itMost often written as “Chronic Fatigue Syndrome” (108), “Fatigue Syndrome, Chronic” (34), and “Cancer-Related Fatigue” (27). The registry filed 1 of them under no condition at all, and the others under other conditions only, most often Fatigue Syndrome, Chronic (172) and Fibromyalgia (32).
  4. −869Match it another way705 name it in the title, 125 in a keyword, and 39 by a synonym or other text the search reads.
  5. 2,222The count on this page136 of them list Fatigue in their own words; the registry filed them under no condition.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Completed
1,360
Recruiting
240
Status unknown
191
Not yet recruiting
148
Terminated
104
Active, not recruiting
82

Phase

Phase 2
191
Phase 3
115
Phase 4
65
Phase 1
54
Early Phase 1
13

Where

United States
704
Turkey
331
France
104
Canada
88
Taiwan
86
Spain
78

Who runs them

M.D. Anderson Cancer Center (33) · Riphah International University (21) · Cairo University (21) · Wake Forest University Health Sciences (20) · Gazi University (18) · Hacettepe University (18) · Centre Hospitalier Universitaire de Saint Etienne (15) · Radicle Science (14)

What is being tested here

Drugs under test in Fatigue studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Modafinil5942
Ponsegromab215
HBS-301222
Methylphenidate11119
Melatonin157
Sildenafil115
Creatine monohydrate103
Creatine103
Solriamfetol102
Bupropion102

Drug classes tested here Stimulants 7 open · PDE5 inhibitors 1 open · Corticosteroids 11 · SNRIs 9 · Potassium channel blockers 7

Coming up

20phase 3 studies under way
142studies finish main data collection within a year8 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 240 Fatigue studies recruiting now, 112 (47%) set no upper age limit and 98 (41%) stop at 75 or younger. 24 (10%) take children under 18. 23 (10%) are for women only and 10 (4%) for men only; 74 (31%) take healthy volunteers.

Recruiting studies that take each age, of 240
AgeWomenMen
1014 (6%)17 (7%)
18188 (78%)188 (78%)
30204 (85%)192 (80%)
40205 (85%)189 (79%)
50200 (83%)184 (77%)
65184 (77%)173 (72%)
75150 (63%)141 (59%)
85125 (52%)118 (49%)

Across all 2,229 studies, recruiting or not: 45% stop at 75 or younger and 36% at 65; 9% take children; 14% are for women only and 6% for men only; 32% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Fatigue studies take

Of 43 phase 2 interventional studies under Fatigue, half reached primary completion within 38 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 123 mo9–40 · 17 studies——
Phase 238 mo20–48 · 43 studies—44 mo26–90 · 35 studies
Phase 331 mo23–61 · 27 studies——
Phase 433 mo21–55 · 15 studies——
Interventional, no phase11 mo5–27 · 989 studies3 mo2–10 · 53 studies12 mo5–27 · 936 studies
Observational24 mo7–42 · 166 studies—22 mo7–61 · 156 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting4

Results posted3

Stopped2

Newly registered21

Show 16 more

Studies

Recruiting first, then most recently updated. Showing 50 of 2,229. Browse all 2,229 → or search them.