Drug class
Phosphodiesterase 5 Inhibitors clinical trials
A class of medicines: the studies that test any of its 12 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones.
Keep track of what changes. Save the phosphodiesterase 5 inhibitors studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesMedicines in this class
Studies that test each. A study of two counts under both, and once above.
- Tunodafil
- 2
- 3-(4-(2-hydroxyethyl)piperazin-1-yl)-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido(3,4-b)pyrazin-2(1H)-one
- 2
- Lodenafil carbonate
- 2
Studies by the year they started
680 studies that test it; most in 2010 (45); 1 more planned to start later
| Year | Studies |
|---|---|
| 1996 | 1 |
| 1998 | 1 |
| 1999 | 2 |
| 2001 | 9 |
| 2002 | 22 |
| 2003 | 43 |
| 2004 | 31 |
| 2005 | 33 |
| 2006 | 33 |
| 2007 | 29 |
| 2008 | 34 |
| 2009 | 37 |
| 2010 | 45 |
| 2011 | 39 |
| 2012 | 29 |
| 2013 | 31 |
| 2014 | 28 |
| 2015 | 35 |
| 2016 | 24 |
| 2017 | 23 |
| 2018 | 17 |
| 2019 | 15 |
| 2020 | 13 |
| 2021 | 23 |
| 2022 | 26 |
| 2023 | 14 |
| 2024 | 15 |
| 2025 | 20 |
| 2026 | 8 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 250 · Other 435
Eli Lilly and Company (49) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (45) · Bayer (45) · VIVUS LLC (17) · Ain Shams University (15) · Pfizer (13) · Assiut University (10) · Beni-Suef University (9)
Studies
Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten.
Testing one of them · 685
- Multimodal Prehabilitation and Rehabilitation for Men Undergoing Robot-Assisted Radical ProstatectomyRecruitingPhase 2Surgical Outcomes Research Centre (SOuRCe)NCT07576335Written as Tadalafil 5 mg
- Effects of Tadalafil on Cognition and Cerebral Hemodynamics in Elderly Patients With Mild Cognitive ImpairmentNot yet recruitingPhase 2Los Angeles Brain Science ProjectNCT07882901Written as Tadalafil 5 mg
- Sildenafil for Early Pulmonary Vascular Disease in SclerodermaRecruitingPhase 2Johns Hopkins UniversityNCT04797286Written as Sildenafil
- A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other OptionRecruitingPhase 3ActelionNCT05179876Written as Macitentan/Tadalafil FDC
- Treatment of Neonatal Encephalopathy With Oral Sildenafil Suspension to Repair Brain Injury Secondary to Birth AsphyxiaRecruitingPhase 2Pia WintermarkNCT06098833Written as Sildenafil
- The Effect of Additive On-Demand Sildenafil vs. Dextrose Candy on Maximum Exercise Capacity in Pulmonary Arterial HypertensionRecruitingPhase 2/3Silvia UlrichNCT07824674Written as Sildenafil 20mg
- Asciminib With or Without Sildenafil for Brain TumorsNot yet recruitingEarly Phase 1Washington University School of MedicineNCT07039760Written as Sildenafil
- The Effects of Mirabegron and Tadalafil on Glucose Tolerance in PrediabeticsRecruitingPhase 4Philip KernNCT05051436Written as Tadalafil 10 MG
- Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary DiseaseRecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT05844462Written as Tadalafil
- Study of Tadalafil vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan PhysiologyRecruitingPhase 3Mayo ClinicNCT05206955Written as Tadalafil
- Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPDRecruitingPhase 2University of AlbertaNCT05061368Written as Sildenafil Citrate
- Tamsulosin With or Without Tadalafil for Trial Without Catheter After Acute Urinary Retention Due to Benign Prostatic HyperplasiaRecruitingPhase 4Beni-Suef UniversityNCT07654413Written as Tadalafil
- L-Citrulline and Tadalafil for Mild to Moderate Erectile DysfunctionRecruitingPhase 4Beni-Suef UniversityNCT07642505Written as Tadalafil
- Vasodilator and Exercise Study for DMD (VASO-REx)RecruitingPhase 2University of FloridaNCT06290713Written as Tadalafil
- Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PHRecruitingPhase 2VA Office of Research and DevelopmentNCT05937854Written as Tadalafil
- Interest of Early Erectile Rehabilitation With Sildenafil After Radiotherapy and Proctectomy for Rectal CancerRecruitingPhase 3University Hospital, RouenNCT06123156Written as Sildenafil
- Sildenafil to Prevent and Reduce Cancer Related Cognitive ImpairmentNot yet recruitingPhase 2/3The University of Texas Medical Branch, GalvestonNCT06800092Written as Sildenafil
- Sildenafil Plus Hypothermia to Treat Neonatal EncephalopathyNot yet recruitingPhase 2Assistance Publique - Hôpitaux de ParisNCT06810284Written as Sildenafil Citrate (IV)
- Effect of Tadalafil on Endometrial Thickness and Frozen Embryo Transfer OutcomesRecruitingPhase 4Beni-Suef UniversityNCT07499804Written as Tadalafil 5mg
- Tadalafil 5 mg on Storage Lower Urinary Tract Symptoms After Anatomical Endoscopic Enucleation of the ProstateNot yet recruitingPhase 1Assiut UniversityNCT07466030Written as Tadalafil 5mg (Male)
See all 685 studies that test one of the phosphodiesterase 5 inhibitors →
Codes
What other systems call Phosphodiesterase 5 Inhibitors · ClinicalTrials.gg INT008935
- MeSH (NLM) D058986Phosphodiesterase 5 InhibitorsOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D058986 | Phosphodiesterase 5 Inhibitors | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.