Signs and Symptoms clinical trials
The registry lists 221 studies for Signs and Symptoms across more than 10 countries. 22 are recruiting or about to start. 44 of them are mainly about Signs and Symptoms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13. Counting its 327 narrower conditions too, such as Obesity: 81,254 studies, 15,907 open.
Get an email when these change. Save the Signs and Symptoms studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
University of California, San Francisco (5) · Vanderbilt University Medical Center (4) · Danish Headache Center (4) · Millet Innovation (4) · University of California, Irvine (4) · OHSU Knight Cancer Institute (3) · Auspex Pharmaceuticals, Inc. (3) · UNC Lineberger Comprehensive Cancer Center (3)
What is being tested here
Drugs under test in Signs and Symptoms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 10, phase 3 first
- Oct 2027A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D) · Phase 3 · Pfizer
- Dec 2026Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease · University of Pennsylvania
- Dec 2026A Useful Support System for Psychiatric Diagnostics and Follow-up in Adult Psychiatry and Primary Care (ASPP) · Karolinska Institutet
- Mar 2027Long-term Follow-up and Quality of Life of Patients Treated With Anticancer Drugs · Institut Rafael
- Mar 2027Selective Activation of the Adrenomedullin Receptors in Migraine · Danish Headache Center
- Aug 2027Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults With Cancer · Virginia Commonwealth University
- Sep 2027Symptom Management and Survivorship Plus Coaching for Advanced Cancer Survivors and Their Caregivers · University of Arizona
- Sep 2027Strain-Counterstrain Treatment of Piriformis Pain · Loma Linda University
- Oct 2027Immunoglobulin G4 and Immunoglobulin E Antibodies in a Population With Adverse Reactions to Foodstuffs-related Symptoms · Universidad Politecnica de Madrid
- Nov 2027BaiXiaoAi AI Companion for Cancer Patient Follow-up · Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Who these studies take
Of the 15 Signs and Symptoms studies recruiting now, 9 (60%) set no upper age limit and 3 (20%) stop at 75 or younger. 1 (7%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 14 (93%) | 14 (93%) |
| 30 | 13 (87%) | 13 (87%) |
| 40 | 13 (87%) | 13 (87%) |
| 50 | 13 (87%) | 13 (87%) |
| 65 | 14 (93%) | 14 (93%) |
| 75 | 12 (80%) | 12 (80%) |
| 85 | 9 (60%) | 9 (60%) |
Across all 221 studies, recruiting or not: 30% stop at 75 or younger and 24% at 65; 14% take children; 11% are for women only and 2% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Signs and Symptoms studies take
Of 69 interventional studies with no phase under Signs and Symptoms, half reached primary completion within 17 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 17 mo6–37 · 69 studies | — | 22 mo8–37 · 58 studies |
| Observational | 16 mo8–20 · 20 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 50 of 221. Browse all 221 → or search them.
- Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery LesionsRecruitingNCT07258290Not applicable4 countries
- A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or ObesityRecruitingNCT07595549Phase 311 countries
- Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults With CancerRecruitingNCT05958316Not applicable1 country
- Selective Activation of the Adrenomedullin Receptors in MigraineRecruitingNCT07451769Not applicable1 country
- Symptom Management and Survivorship Plus Coaching for Advanced Cancer Survivors and Their CaregiversRecruitingNCT07415564Not applicable1 country
- Biomedical Signal Extraction From Symptom Descriptions: An Observational Registry Using the OpenGenome PlatformRecruitingNCT075786101 country
- Integrative Oncology for Patient SymptomsRecruitingNCT04940780Not applicable1 country
- Strain-Counterstrain Treatment of Piriformis PainRecruitingNCT05023005Not applicable1 country
- BaiXiaoAi AI Companion for Cancer Patient Follow-upNot yet recruitingNCT07396142
- Amylin-Induced Migraine Attacks Without AuraNot yet recruitingNCT07340788Not applicable1 country
- Hypersensitivity to Amylin in Post-Traumatic HeadacheNot yet recruitingNCT07340775Not applicable1 country
- Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery PatientsRecruitingNCT04289142Phase 41 country
- Personalized Treatment by rTMS in Chronic Pain - Study2RecruitingNCT07247552Not applicable1 country
- Predictive and Impact of Pain After 6 Months of Radiotherapy, in Head and Neck CancerRecruitingNCT05505188Not applicable1 country
- Long-term Follow-up and Quality of Life of Patients Treated With Anticancer DrugsRecruitingNCT063177141 country
- Efficacy of Hypno-ear-acupuncture on Insomnia in Advanced Cancer PatientsNot yet recruitingNCT06532188Not applicable1 country
- Effects of Telemonitoring in Quality of Life Amongst Cancer PatientsRecruitingNCT06086990Not applicable1 country
- STASSH - TRAUMA - Absorbable vs Non-Absorbable Sutures in Trauma Hand SurgeryNot yet recruitingNCT06247761Not applicable
- A Useful Support System for Psychiatric Diagnostics and Follow-up in Adult Psychiatry and Primary Care (ASPP)RecruitingNCT058274061 country
- Construction of Symptom Network in Maintenance Hemodialysis PatientsNot yet recruitingNCT058379881 country
- Immunoglobulin G4 and Immunoglobulin E Antibodies in a Population With Adverse Reactions to Foodstuffs-related SymptomsRecruitingNCT056819751 country
- Microbiota and Symptom Distress in Head and Neck Cancer Patients Receiving RadiotherapyNot yet recruitingNCT04843644Not applicable
- Effectiveness of a Music Therapy Intervention in Cancer Patients Undergoing Active Treatment at the Jaén University HospitalCompletedNCT07886658Not applicable1 country
- The Effect of Olfactory Mental Imagery and Cardiovascular SurgeryCompletedNCT06221436Not applicable1 country
- The Effect of Tecar Therapy in Patients With Chronic Neck PainCompletedNCT07907874Not applicable1 country
- The Effect of Acupressure on Pain, Menstrual Symptoms, and General Comfort in Adolescents With Primary DysmenorrheaCompletedNCT05408611Not applicable1 country
- A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D)Active, not recruitingNCT07400653Phase 311 countries
- Pictorial Support in Person-centred Care for Children (PicPecc)CompletedNCT04433650Not applicable1 country
- Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver DiseaseActive, not recruitingNCT06136221Not applicable1 country
- A Mobile Health Intervention to Achieve Appropriate Gestational Weight Gain in Overweight/Obese WomenCompletedNCT03880461Not applicable1 country
- Addressing Involuntary Movements in Tardive DyskinesiaCompletedNCT02291861Phase 36 countries
- Symptom Care at Home-Heart FailureCompletedNCT04347759Not applicable1 country
- Confirm Rx Insertable Cardiac Monitor SMART RegistryCompletedNCT0350580124 countries
- Postural and Muscle Fatigue Analysis of Endodontic ResidentsCompletedNCT062826531 country
- Implementation Strategies for Monitoring Adherence in Real TimeActive, not recruitingNCT04347161Not applicable1 country
- Validation of Withings Sleep for the Detection of Sleep Apnea SyndromeActive, not recruitingNCT042348282 countries
- Title: Leveraging Technology to Address Health Outcomes of Cancer SurvivorsCompletedNCT05499663Phase 1/21 country
- A Study to Support the Development of the Enhanced Fluid Assessment Tool for Patients With Acute Kidney InjuryActive, not recruitingNCT055383511 country
- Effect of Using Bitter Melon, Blueberries and Cranberries on HbA1c and Diabetes Symptom LevelsCompletedNCT07233460Not applicable1 country
- Blinded Consumer Study for the Evaluation of the Usability and Efficacy of One Medical Device in Venous ReturnCompletedNCT07234240Not applicable1 country
- Clinical Signs and Activity Limitations Associated With Dural Ectasia in Patients With Marfan DiseaseCompletedNCT051233391 country
- Yoga-Based Breathing Exercise, Colorectal Cancer SurgeryCompletedNCT06446999Not applicable1 country
- COVID-19 And Lingering Symptoms In Primary Care PatientsCompletedNCT0481373111 countries
- Treatment of Post-Operative Pain Following Orthopedic Surgery With SPRINT® Peripheral Nerve Stimulation (PNS) SystemCompletedNCT04341948Not applicable1 country
- Digital Storytelling in Symptom Management Pediatric OncologyCompletedNCT06436651Not applicable1 country
- CZI Rare As One: Co-designing an App and Wearable Based Compass for Rare DiseasesCompletedNCT069079531 country
- Treatment for Persistently Fatigued Cancer Survivors: A Randomized Controlled Trial With Biomarker ResponseCompletedNCT01919853Not applicable1 country
- Effect of Aloe Vera Gel as an Intra Canal MedicamentCompletedNCT06243601Not applicable1 country
- Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child AdversityCompletedNCT04606199Not applicable1 country
- Examine the Effects of Mindfulness in Woman With a History of Child AdversityCompletedNCT05255380Not applicable1 country