Drug
Sildenafil clinical trials
Also written Viagra and Revatio.
- studies test it
- 334
- open now
- 17
- in phase 3
- 76
- first study started
- 1999
Keep track of what changes. Save the sildenafil studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Studies by the year they started
331 studies that test it; most in 2015 (24); 1 more planned to start later
| Year | Studies |
|---|---|
| 1999 | 1 |
| 2001 | 5 |
| 2002 | 12 |
| 2003 | 15 |
| 2004 | 13 |
| 2005 | 17 |
| 2006 | 13 |
| 2007 | 15 |
| 2008 | 19 |
| 2009 | 12 |
| 2010 | 16 |
| 2011 | 23 |
| 2012 | 13 |
| 2013 | 16 |
| 2014 | 11 |
| 2015 | 24 |
| 2016 | 16 |
| 2017 | 13 |
| 2018 | 14 |
| 2019 | 11 |
| 2020 | 6 |
| 2021 | 12 |
| 2022 | 9 |
| 2023 | 7 |
| 2024 | 5 |
| 2025 | 10 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 9
- Phase 1
- 61
- Phase 2
- 92
- Phase 3
- 76
- Phase 4
- 86
- No phase
- 41
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 75 · Other 259
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (45) · Ain Shams University (12) · The University of Texas Medical Branch, Galveston (7) · Assiut University (7) · Duke University (7) · Pfizer (5) · National Jewish Health (4) · Johns Hopkins University (4)
Often tested with
Tested in the same studies.
Tadalafil (12) · Arginine (4) · Bosentan (3) · Sitaxsentan (3) · Riociguat (2) · Metoprolol (2) · Losartan (2) · Pentoxifylline (2)
Studies
Open first, then newest update. How each study uses sildenafil is read from its arms, and is right about nine times in ten.
Testing it · 334
- Sildenafil for Early Pulmonary Vascular Disease in SclerodermaRecruitingPhase 2Johns Hopkins UniversityNCT04797286Written as Sildenafil
- Treatment of Neonatal Encephalopathy With Oral Sildenafil Suspension to Repair Brain Injury Secondary to Birth AsphyxiaRecruitingPhase 2Pia WintermarkNCT06098833Written as Sildenafil
- The Effect of Additive On-Demand Sildenafil vs. Dextrose Candy on Maximum Exercise Capacity in Pulmonary Arterial HypertensionRecruitingPhase 2/3Silvia UlrichNCT07824674Written as Sildenafil 20mg
- Asciminib With or Without Sildenafil for Brain TumorsNot yet recruitingEarly Phase 1Washington University School of MedicineNCT07039760Written as Sildenafil
- Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPDRecruitingPhase 2University of AlbertaNCT05061368Written as Sildenafil Citrate
- Interest of Early Erectile Rehabilitation With Sildenafil After Radiotherapy and Proctectomy for Rectal CancerRecruitingPhase 3University Hospital, RouenNCT06123156Written as Sildenafil
- Sildenafil to Prevent and Reduce Cancer Related Cognitive ImpairmentNot yet recruitingPhase 2/3The University of Texas Medical Branch, GalvestonNCT06800092Written as Sildenafil
- Sildenafil Plus Hypothermia to Treat Neonatal EncephalopathyNot yet recruitingPhase 2Assistance Publique - Hôpitaux de ParisNCT06810284Written as Sildenafil Citrate (IV)
- Sildenafil to Reduce Vascular Remodeling During Left Ventricular Assist Device SupportRecruitingEarly Phase 1Montefiore Medical CenterNCT06510322Written as Sildenafil
- IMProving DRug Dosing and Outcomes for Single VEntricle Patients With Fontan Associated Liver DiseaseRecruitingPhase 1Children's Mercy Hospital Kansas CityNCT06324396Written as Sildenafil 10mg oral tablet (participants <20kg), or 20mg oral tablet (participants ≥20kg)
- Combination Therapy of Tadalafil 2.5mg Plus Sildenafil 25mg Versus Tadalafil 5 mg Monotherapy for Treatment of Erectile Dysfunction: A Randomized, Placebo-Controlled Double-Blinded Cross-Over StudyNot yet recruitingPhase 3Assiut UniversityNCT07177326Written as Sildenafil 25 mg
- Comparison Between Treatments of OligohydramniosRecruitingPhase 2Kafrelsheikh UniversityNCT07135037Written as Sildenafil 25 MG
- A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH)RecruitingPhase 2University of UtahNCT05201144Written as Sildenafil Oral Suspension
- Study to Compare the Effects of Viagra® Vs Hezkue® in Healthy Fasted Male Participants.Not yet recruitingPhase 1Aspargo Labs, IncNCT06782659Written as Viagra
- Preoperative Sildenafil Administration for HepatectomyRecruitingNot applicableFirst People's Hospital of ChenzhouNCT06237751Written as Sildenafil 100 MG
- Effect of Tadalafil, Sildenafil and Pentoxyfylline on Frozen Embryo Transfer OutcomesNot yet recruitingPhase 2/3Beni-Suef UniversityNCT05971667Written as Sildenafil
- The Effect of Sildenafil Citrate on Frozen Embryo Transfer CyclesRecruitingPhase 2/3Beni-Suef UniversityNCT05951413Written as Sildenafil Citrate
- Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT)CompletedPhase 2/3Sindh Institute of Cardiovascular DiseasesNCT07462260Written as Sildenafil 25 MG
- Sildenafil to Repair Brain Injury Secondary to Birth AsphyxiaCompletedPhase 1McGill University Health Centre/Research Institute of the McGill University Health CentreNCT04169191Written as Sildenafil Citrate
- Finding Solutions to Thrive After Birth Asphyxia in AfricaCompletedPhase 1Pia WintermarkNCT05275725Written as Sildenafil
See all 334 studies that test sildenafil →
Given in every arm · 17 — sildenafil is usual care beside what is tested
- Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic SclerosisRecruitingPhase 2Topadur Pharma AGNCT06954597Written as Sildenafil
- PEnile ReHABilitation After Nerve Sparing Robot-assisted Radical Prostatectomy for Prostate Cancer 2.0 (PEHAB-II)RecruitingPhase 4The Netherlands Cancer InstituteNCT06875258Written as Sildenafil
- Nebulized Magnesium Sulfate and Sildenafil for Persistent Pulmonary Hypertension of NewbornRecruitingPhase 1/2Sohag UniversityNCT04898114Written as Sildenafil Citrate
- Delayed Dose Collagenase Clostridium Histolyticum (CCH) Protocol for Men With Peyronie's DiseaseActive, not recruitingPhase 4Charitable Union for the Research and Education of Peyronie's DiseaseNCT06649539Written as Sildenafil
- Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study)CompletedPhase 1ShionogiNCT04481789Written as Sildenafil
- Combination Therapy in Pulmonary Arterial HypertensionCompletedPhase 4ActelionNCT00433329Written as Sildenafil
- Efficacy of Milrinone With Sildenafil in Persistent Pulmonary Hypertension in ChildrenCompletedNot applicableMuhammad Aamir LatifNCT06562036Written as Sildenafil
- A Study to Investigate the Efficacy of PADN to Improved Functional Capacity and Hemodynamics in Patients With PAHTerminatedPhase 4Nanjing First Hospital, Nanjing Medical UniversityNCT02284737Written as Sildenafil
- Evaluation of Metabolic Markers for the Prediction of DDI of Various CYP3A Substrates and InhibitorsCompletedPhase 1Seoul National University HospitalNCT02975037Written as Sildenafil
- Nivolumab With Chemotherapy in Refractory MDSTerminatedPhase 1/2St. Petersburg State Pavlov Medical UniversityNCT03259516Written as Sildenafil
- ED Recovery in Men Age </=65 Treated With Bilateral Nerve Sparing Robotic Assisted Prostatectomy for Prostate CancerTerminatedPhase 3City of Hope Medical CenterNCT00544076Written as sildenafil citrate
- Effect of Testosterone in Men With Erectile DysfunctionCompletedPhase 4Boston UniversityNCT00512707Written as Sildenafil citrate (open label)
- Testosterone for Penile Rehabilitation After Radical ProstatectomyTerminatedEarly Phase 1Mohit KheraNCT00848497Written as Viagra®
- Comparison of Efficacy Different Treatment Regimens in Pulmonary Hypertension Secondary to Lung Disease and or HypoxiaStatus unknownPhase 4All India Institute of Medical Sciences, New DelhiNCT01449253Written as Sildenafil
- Effect of Adding Sildenafil to Protocol of Endometrial Preparation in Outcome of Frozen-thawed Embryo Transfer CyclesCompletedPhase 4farzaneh hojjatNCT01668446Written as Sildenafil
- Study of Add-on Ambrisentan Therapy to Background Phosphodiesterase Type-5 Inhibitor (PDE5i) Therapy in Pulmonary Arterial Hypertension (ATHENA-1)CompletedPhase 4Gilead SciencesNCT00617305Written as Sildenafil
- SAR407899 Single-dose in Treatment of Mild to Moderate Erectile DysfunctionCompletedPhase 2SanofiNCT00914277Written as Sildenafil
As the comparator · 25 — what is tested is compared with sildenafil
- Randomized Study of Triple Therapy vs Sildenafil Dose Optimization in Pulmonary Arterial HypertensionRecruitingPhase 4University of Sao Paulo General HospitalNCT07713914Written as Sildenafil Dose Optimization
- A Study to Assess the Safety, Tolerability and Pharmacokinetics of Viaca (Sildenafil + Cabergoline) Compared With Sildenafil and CabergolineNot yet recruitingPhase 1Yanping KongNCT07732387Written as Sildenafil 50 mg
- Phase 2 Efficacy Study of Sildenafil Products in Adult Men With Erectile DysfunctionNot yet recruitingPhase 2Aspargo Labs, IncNCT07231185Written as Pfizer Viagra
- Vardenafil Vs Sildenafil for the Treatment of Pulmonary Hypertension of the NewbornCompletedPhase 1/2Damascus UniversityNCT06860399Written as Sildenafil
- Clinical Observation of Ningmitai Capsule in Treating Chronic Pelvic Pain Syndrome With Erectile DysfunctionCompletedPhase 4Xintian PharmaceuticalNCT06064448Written as Sildenafil
- Pharmacodynamic Study to Assess the Effects of Repeated Dosing of SAR247799 on Endothelial Function in Patients With Type 2 Diabetes MellitusCompletedPhase 1SanofiNCT03462017Written as Sildenafil
- Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapyCompletedPhase 4BayerNCT02891850Written as Sildenafil
- A Bioequivalence Study of Sildenafil Citrate Orally-Disintegrating Film Dosage FormWithdrawnPhase 1Pfizer's Upjohn has merged with Mylan to form Viatris Inc.NCT04391868Written as Viagra Tablet
- Bioavailability of 3 Sildenafil Oral Disintegrating Tablet Formulations Compared to the Standard Oral TabletCompletedPhase 1Pfizer's Upjohn has merged with Mylan to form Viatris Inc.NCT00950404Written as Viagra 50 mg tablet
- Pharmacokinetics Of Sildenafil Orally Disintegrating Tablet Formulation Versus To Viagra® Oral Tablet.CompletedPhase 1Pfizer's Upjohn has merged with Mylan to form Viatris Inc.NCT01254383Written as Sildenafil Tablet
- Bioequivalence Study For Orally-Disintegrating Tablet Of SildenafilCompletedPhase 1Pfizer's Upjohn has merged with Mylan to form Viatris Inc.NCT01737203Written as Viagra
- Psychotherapy and Pharmacotherapy in the Treatment of Erectile Dysfunction: A Pilot StudyCompletedNot applicableInternational Islamic University, IslamabadNCT04179747Written as Sildenafil Citrate 50Mg Tab
- Efficacy and Safety of Nintedanib Co-administered With Sildenafil in Idiopathic Pulmonary Fibrosis Patients With Advanced Lung Function ImpairmentCompletedPhase 3Boehringer IngelheimNCT02802345Written as Sildenafil
- Safety and Efficacy of TD0025 (Rocket1h) for Treatment of Erectile DysfunctionCompletedPhase 2/3Vietstar Biomedical ResearchNCT02798159Written as Sildenafil Citrate 50mg
- Comparative Study of Strategies for Management of Duchenne Myopathy (DM)Status unknownPhase 4Assiut UniversityNCT03633565Written as Sildenafil (Phosphodiesterase inhibitors)
- Efficacy of Beraprost in Lowering Pulmonary Arterial Pressure in ChildrenCompletedPhase 4Dr. Soetomo General HospitalNCT03431649Written as Sildenafil Citrate
- A Research Study To Assess The Effectiveness And Safety Of Different Doses Of Oral PF-00489791 In The Treatment Of Adult Patients With Pulmonary Arterial HypertensionTerminatedPhase 2PfizerNCT00853112Written as sildenafil
- Topical 10 % Nifedipine Versus 5% Sildenafil in Secondary RaynaudCompletedEarly Phase 1Pontificia Universidad Catolica de ChileNCT03027674Written as 5% sildenafil cream
- Nebivolol in the Supine Hypertension of Autonomic FailureCompletedNot applicableVanderbilt UniversityNCT01044693Written as Sildenafil25 mg
- FDA Phase IV - Commitment - Retinal Function StudyCompletedPhase 4BayerNCT00461565Written as Sildenafil
Showing 20 of 25.
Codes
What other systems call sildenafil · ClinicalTrials.gg INT006527
- MeSH (NLM) D000068677Sildenafil CitrateConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 3M7OB98Y7HSILDENAFILConfirmed FDA, NLM, Wikidata
- RxNorm 136411Confirmed FDA, Wikidata
- Wikidata Q191521sildenafilConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61940SildenafilOne source FDA
- DrugBank DB00203One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000068677 | Sildenafil Citrate | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 3M7OB98Y7H | SILDENAFIL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 136411 | — | Confirmed FDA, Wikidata |
| Wikidata | Q191521 | sildenafil | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61940 | Sildenafil | One source FDA |
| DrugBank | DB00203 | — | One source Wikidata |
Also registered as acetildenafil (UNII TP0E2BW57H), desmethylsildenafil (UNII L6WO34R9YG), homosildenafil (UNII 0Z3JH0S0QK) and lodenafil (UNII 80X7B1F6NW).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.