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RecruitingNCT06727903VITAUpdated Dec 2, 2025

Predictive Model for Mortality in Older People With Critical Illness

An observational study in Critical Illness, sponsored by Consorci Sanitari de l'Alt Penedès i Garraf. Recruiting at 15 sites in Spain. Open to participants aged 75 Years and older. Per ClinicalTrials.gov, last updated 2025-12-02.

Sponsored by Consorci Sanitari de l'Alt Penedès i Garraf · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
450
Ages
75 Years and older
Sex
All
01

Study summary

The present study aims to develop a predictive model to identify elderly patients with the highest likelihood of mortality upon admission to an intensive care unit.

02

Conditions studied

  • Critical Illness

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Keywords

  • Critical Illness
  • Mortality
  • Aged
  • Intensive Care Units
03

Who can participate

Ages eligible
75 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients admitted to a Intensive Care Unit

Inclusion criteria

  • Men and women aged 75 or older.
  • Admission to an ICU from the Emergency Department.
  • Availability of or possibility to contact a participant's informant.
  • Informed consent for participation in the study, either by the participant or a valid legal representative.

Exclusion criteria

Exclusion Criteria:

Participants meeting any of the following exclusion criteria will not be included in the study:

  • Patients transferred to the Emergency Department from a hospital ward.
  • Patients who die within the first 24 hours of ICU admission.
  • Patients admitted to Step-Down Units.
  • Patients requiring ICU admission for any of the following reasons:

Orotracheal intubation or advanced cardiopulmonary resuscitation performed prior to arrival at the Emergency Department.

AV block awaiting pacemaker implantation. Activation of the STEMI or Stroke care pathway. Post-cardiac catheterization for acute coronary syndrome.

  • Participation in another clinical study involving an intervention, procedure, or visit schedule that is incompatible with the present study.
04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
450 participants (estimated)
Patient registry
No

Interventions

  • Otherlaboratory biomarker analysis

    Results of laboratory biomarker analysis will be analyzed as predictors for mortality

05

What researchers measure

Primary outcomes

  1. mortality

    mortality on day 90 from admission to Intensive Care Unit

    Time frame: Day 90

06

Study locations

1 of 15 sites recruiting
  • Hospital German Trias i Pujol
    Badalona, Barcelona 08916, Spain
    • Clarissa Catalano, MD · Contact · ccatalanonada@gmail.com · 0034934651200
    • Regina Roig, MD · Principal investigator
    Recruiting
  • Consorci Sanitari Alt Penedès-Garraf
    Sant Pere de Ribes, Barcelona 08810, Spain
    • Fernando Gerber · Contact · jfgerber@csapg.cat · 0034938960025
    • Noemí Casaponsa · Contact · recerca@csapg.cat · 0034938960025
    • Fernando Gerber, MD · Principal investigator
    Not yet recruiting
  • Hospital Clinic
    Barcelona, Spain
    • Pedro Castro · Contact · pcastro@clinic.cat · 0034932 27 54 00
    • Pedro Castro · Principal investigator
    Not yet recruiting
  • Hospital de Barcelona
    Barcelona, Spain
    • Karla Núñez · Contact · kanuvaz@gmail.com · 0034932 54 24 00
    • Karla Núñez · Principal investigator
    Not yet recruiting
  • Hospital de la Santa Creu i Sant Pau
    Barcelona, Spain
    • Carles Subirà · Contact · CSubira@santpau.cat · 0034932 91 90 00
    • Carles Subirà · Principal investigator
    Not yet recruiting
  • Hospital de Mataró
    Barcelona, Spain
    • Estel Güell · Contact · eguell@csdm.cat · 0034937 41 77 00
    • Estel Güell · Principal investigator
    Not yet recruiting
  • Hospital de Terrassa
    Barcelona, Spain
    • Manuel Buitrago · Contact · MBuitrago@CST.CAT · 0034937 31 00 07
    • Manuel Buitrago · Principal investigator
    Not yet recruiting
  • Hospital del Mar
    Barcelona, Spain
    • Ana Zapatero · Contact · azapatero@psmar.cat · 0034932 48 30 00
    • Ana Zapatero · Principal investigator
    Not yet recruiting
  • Hospital Dexeus Barcelona
    Barcelona, Spain
    Not yet recruiting
  • Hospital General de Catalunya
    Barcelona, Spain
    • María Dolores Bosque · Contact · mdbosque@quironsalud.es · 0034900 301 013
    • María Dolores Bosque · Principal investigator
    Not yet recruiting
  • Hospital General de Granollers
    Barcelona, Spain
    Not yet recruiting
  • Hospital Sagrat Cor
    Barcelona, Spain
    Not yet recruiting
  • Clinica Girona
    Girona, Spain
    Not yet recruiting
  • Hospital Santa Caterina
    Girona, Spain
    Not yet recruiting
  • Hospital Universitari Dr. Josep Trueta
    Girona, Spain
    Not yet recruiting
07

References and documents

Individual participant data

Plan to share: Yes — IPD (without personal identification data) could be shared by requirement from other researchers after the end of the study, and only for research purposes and previous approval of promotor center of the study (CSAPG). Anyway, Spanish and European Union legal policy about data protection will strictly be followed (IPD will not be transferred outside European Union).

Supporting information: Study protocol, Icf

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT06727903
Lead sponsor
Consorci Sanitari de l'Alt Penedès i Garraf
Responsible party
Sponsor
First posted
Dec 11, 2024
Start date
Mar 20, 2025
Primary completion
Dec 2026 (estimated)
Completion
Dec 2026 (estimated)
Last update
Dec 2, 2025

Study contacts

César Gálvez, Ph.D.
Contact
cgalvez@csapg.cat
+34 9389600325
Noemí Casaponsa
Contact
recerca@csapg.cat
+34 938960025 ext. 43197

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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