Drug class
Proton Pump Inhibitors clinical trials
A class of medicines: the studies that test any of its 9 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones.
Keep track of what changes. Save the proton pump inhibitors studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesMedicines in this class
Studies that test each. A study of two counts under both, and once above.
- Omeprazole, sodium bicarbonate drug combination
- 5
Studies by the year they started
872 studies that test it; most in 2006 (64)
| Year | Studies |
|---|---|
| 1995 | 2 |
| 1996 | 2 |
| 1998 | 4 |
| 1999 | 1 |
| 2000 | 4 |
| 2001 | 14 |
| 2002 | 24 |
| 2003 | 28 |
| 2004 | 32 |
| 2005 | 44 |
| 2006 | 64 |
| 2007 | 33 |
| 2008 | 59 |
| 2009 | 36 |
| 2010 | 53 |
| 2011 | 41 |
| 2012 | 28 |
| 2013 | 46 |
| 2014 | 42 |
| 2015 | 32 |
| 2016 | 32 |
| 2017 | 30 |
| 2018 | 37 |
| 2019 | 24 |
| 2020 | 28 |
| 2021 | 24 |
| 2022 | 20 |
| 2023 | 23 |
| 2024 | 33 |
| 2025 | 19 |
| 2026 | 13 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 448 · Other 437
AstraZeneca (97) · Takeda (51) · Boehringer Ingelheim (23) · Pfizer (15) · National Taiwan University Hospital (14) · Il-Yang Pharm. Co., Ltd. (13) · Eisai Inc. (12) · Chinese University of Hong Kong (12)
Studies
Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten.
Testing one of them · 885
- Assessing the Effect of a Proton Pump Inhibitor on the Pharmacokinetics of DZD8586 in Healthy Participants (TAI-SHAN21)Not yet recruitingPhase 1Dizal PharmaceuticalsNCT07888569Written as Rabeprazole
- A Phase I Study of the Interaction of D-2570 With Other Drugs in Healthy AdultsNot yet recruitingPhase 1InventisBio Co., LtdNCT07875842Written as Omeprazole
- A Study to Investigate the Effect of Omeprazole and Cyclosporine on Velzatinib in Healthy ParticipantsNot yet recruitingPhase 1GlaxoSmithKlineNCT07862114Written as Omeprazole
- Effect of Omeprazole on Gut Microbiota in Adults With Obesity and GERDNot yet recruitingPhase 4Federal State Budgetary Scientific InstitutionNCT07850960Written as Omeprazole
- Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori InfectionRecruitingPhase 3Tanta UniversityNCT07275827Written as proton pump inhibitor + amoxicillin
- Neuroregulators for the Treatment of Diseases Associated With Esophageal-brain-gut Axis Communication Abnormalities.RecruitingNot applicableHualien Tzu Chi General HospitalNCT06778824Written as Takepron
- Efficacy And Safety of Bismuth-Tetracycline-Rabeprazole Triple For First-Line Eradication of Helicobacter Pylori InfectionNot yet recruitingNot applicableChih-An Shih, MDNCT07788053Written as Bismuth quadruple therapy
- Esomeprazole and Radiation Induced EsophagitisRecruitingPhase 2Rush University Medical CenterNCT06120803Written as Esomeprazole 40 mg
- The Effect of Proton Pump Inhibitors(PPIs) on Endoscopic Treatment of Walled-off Necrosis (WON)RecruitingNot applicableQilu Hospital of Shandong UniversityNCT07488299Written as Proton Pump Inhibitors
- Assessing the Role of Proton Pump Inhibitors in Reducing Aspiration Incidence in Pediatric Laryngomalacia CasesRecruitingNot applicableMinia UniversityNCT07750379Written as PPI
- Reducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous ThromboembolismRecruitingPhase 3Ottawa Hospital Research InstituteNCT06393868Written as Omeprazole 20 mg Oral Tablet
- A Study to Compare How CHF10196 (Florensocatib) is Absorbed Into the Blood When Given Alone and With a Drug That Reduces Stomach Acid in Healthy Male ParticipantsNot yet recruitingPhase 1Chiesi Farmaceutici S.p.A.NCT07683793Written as Pantoprazole
- Efficacy of Ketorolac for Postoperative Pain Management in Hip ArthroscopyRecruitingPhase 4Henry Ford Health SystemNCT07037888Written as Omeprazole
- A Study of Esomeprazole in Children With AutismRecruitingPhase 2Stanford UniversityNCT03866668Written as Esomeprazole
- GERD Infant Feeding Therapeutics Trial (GIFT Trial)RecruitingNot applicableNationwide Children's HospitalNCT06114836Written as Omeprazole
- PPIs and In-Hospital Morbidity in Acute Variceal Bleeding With Chronic Liver DiseaseRecruitingPhase 2Universidad Autonoma de Nuevo LeonNCT06861478Written as Omeprazole 40 mg IV
- Evaluating the Pharmacokinetics of Oregano and Potential Oregano-drug Interactions Using a Drug Cocktail ApproachRecruitingEarly Phase 1Washington State UniversityNCT06693960Written as Drug cocktail
- Effect of Triple Versus Quadruple Therapy for Treating Helicobacter Pylori InfectionEnrolling by invitationNot applicableAkil Al IslamNCT07010744Written as Quadruple therapy
- Effect of ZaStaprazan on Platelet Reactivity of Clopidogrel After PercuTaneous CoronAry InteRventionRecruitingPhase 4Yonsei UniversityNCT07471867Written as Rabeprazole
- Fatty Acid Synthase Inhibition in Castration Refractory Prostate CancerRecruitingPhase 2Wake Forest University Health SciencesNCT04337580Written as Omeprazole 80 mg twice daily
See all 885 studies that test one of the proton pump inhibitors →
Codes
What other systems call Proton Pump Inhibitors · ClinicalTrials.gg INT008901
- MeSH (NLM) D054328Proton Pump InhibitorsOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D054328 | Proton Pump Inhibitors | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.